Dive into the world of antimalarial drugs with 88 Diagnoses! This episode unpacks everything from the UpToDate article on antimalarial drugs, covering mechanisms, resistance patterns, and toxicities. Learn how drugs like artemisinin derivatives, quinoline derivatives, and antifolates target the malaria parasite’s life cycle. With 3 snappy segments featuring catchy mnemonics, 4-5 ward-ready tips, relatable resident stories, and 3-4 ‘pause and think’ prompts, we wrap up with an interactive case study with a diagnostic twist. Each subtopic ends with “if you can’t remember everything, remember this” for quick recall. Listen now, apply a tip on rounds, and share your feedback to ace malaria management!

Dive into acute pancreatitis with this episode of 88 Diagnoses! Covering everything from the UpToDate article, we break down the inflammatory pancreatic condition—its classification (interstitial vs. necrotizing), severity (mild to severe), clinical symptoms like hallmark pain, and key diagnostic tools like serum lipase and CT/MRI. Expect 3 snappy segments with catchy mnemonics, 4-5 ward-ready tips, relatable resident stories, and 3-4 ‘pause and think’ prompts to sharpen your skills. Each subtopic wraps with “if you can’t remember everything, remember this!” We end with an interactive case study featuring a diagnostic twist. Listen now, apply a tip on rounds, and share your feedback to ace pancreatitis on the wards!

Tackle severe malaria in this high-energy 88 Diagnoses episode, drawn directly from the UpToDate article! Explore urgent diagnosis, antimalarial therapy with artesunate, and supportive care for complications like seizures, anemia, and acute kidney injury. Learn management protocols, including the Blantyre Coma Score and malarial retinopathy, with a focus on special populations like pregnant patients. Get 3 mnemonic-packed segments, 4-5 ward-ready tips, resident anecdotes, 3-4 ‘pause and think’ prompts, and a case study with a diagnostic twist. Each subtopic ends with “if you can’t remember everything, remember this!” Listen now, apply a tip on rounds, and share feedback to master severe malaria!

Explore the management of acute pancreatitis in this 88 Diagnoses episode, drawn straight from the UpToDate article! Learn about initial assessment, fluid therapy, pain control, and severity-based care, plus how to tackle complications like necrosis and fluid collections. We cover interventions and treating root causes like gallstones or alcohol use. Enjoy 3 mnemonic-packed segments, 4-5 practical tips, resident anecdotes, 3-4 ‘pause and think’ prompts, and a case study with a diagnostic twist. Each subtopic ends with “if you can’t remember everything, remember this!” Listen now, apply a tip on rounds, and share your feedback to master pancreatitis management!

This episode explores the critical topic of infections in older adults, drawing directly from the detailed insights provided by UpToDate. It covers why older adults are more susceptible to infections due to age-related physiological and immunological changes, as well as societal factors. The podcast highlights atypical presentations, modified fever definitions, and the need for a lower threshold of suspicion in this population. It also delves into antibiotic management, addressing altered pharmacokinetics, the risk of multidrug-resistant organisms, and the importance of antibiotic stewardship. Specific infectious syndromes like UTIs and pneumonia are discussed, along with immunization and travel considerations. Each subtopic concludes with the memorable phrase, “if you can’t remember everything, remember this,” ensuring residents retain the most critical points for effective patient care.

This episode tackles the diverse etiologies of Fever of Unknown Origin (FUO) in adults, based entirely on the comprehensive content from UpToDate. It defines FUO as a prolonged fever without an obvious cause after extensive evaluation and organizes its causes into five main categories: infections, rheumatologic conditions, neoplasms, miscellaneous causes, and undiagnosed cases. The podcast explores how epidemiology varies by geography, patient age, and even climate change’s impact on infectious causes, with examples like tuberculosis, adult-onset Still’s disease, cancers, and conditions such as sarcoidosis or factitious fever. Each subtopic is summarized with the key phrase, “if you can’t remember everything, remember this,” to help residents retain the essential diagnostic insights needed to navigate this challenging clinical puzzle.

This episode dives into the comprehensive evaluation and management of Fever of Unknown Origin (FUO) in adults, based entirely on the authoritative content from UpToDate. It covers the definition of FUO as a prolonged fever without an identifiable cause despite thorough investigation, exploring its four key categories: classic, healthcare-associated, immunocompromised, and travel-associated. The podcast walks through a systematic approach, emphasizing the critical role of a detailed patient history, thorough physical exams, and initial diagnostic tests, as well as advanced steps like targeted testing, biopsies, and imaging such as PET/CT. It also discusses patient outcomes, including spontaneous resolution and prognosis. Each subtopic wraps up with the key takeaway, “if you can’t remember everything, remember this,” to reinforce essential points for residents navigating this complex diagnostic challenge.

Description: This episode provides a detailed exploration of the clinical manifestations, diagnosis, and differential diagnoses of dermatomyositis (DM) and polymyositis (PM), two immune-mediated myopathies, as outlined in the UpToDate articles. It covers the hallmark features of muscle weakness and inflammation, with a focus on DM’s distinctive skin manifestations and the variant clinically amyopathic DM (CADM). The podcast delves into epidemiology, key clinical signs, laboratory findings, and diagnostic approaches, including the role of imaging and muscle biopsies to distinguish DM and PM from conditions like inclusion body myositis (IBM) and immune-mediated necrotizing myopathy (IMNM). Grounded in UpToDate’s comprehensive insights, each subtopic wraps up with a practical takeaway, highlighted by "if you can’t remember everything, remember this," to support residents in mastering these complex conditions.