Fever of Unknown Origin in Adults: Evaluation and Management for Residents
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Fever of Unknown Origin in Adults: Evaluation and Management for Residents
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This episode dives into the comprehensive evaluation and management of Fever of Unknown Origin (FUO) in adults, based entirely on the authoritative content from UpToDate. It covers the definition of FUO as a prolonged fever without an identifiable cause despite thorough investigation, exploring its four key categories: classic, healthcare-associated, immunocompromised, and travel-associated. The podcast walks through a systematic approach, emphasizing the critical role of a detailed patient history, thorough physical exams, and initial diagnostic tests, as well as advanced steps like targeted testing, biopsies, and imaging such as PET/CT. It also discusses patient outcomes, including spontaneous resolution and prognosis. Each subtopic wraps up with the key takeaway, “if you can’t remember everything, remember this,” to reinforce essential points for residents navigating this complex diagnostic challenge.