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  • Sarah Karpen, PA-C, Stem Cell Therapies at UC San Diego

    Sarah Karpen, PA-C, Stem Cell Therapies at UC San Diego
    2025/08/22
    This episode features our conversation with Sarah Karpen, PA-C, who serves as an APP supervisor with the Alpha Clinic, CRM service, and Sanford Stem Cell Clinical Center at UC San Diego. Sarah provides an overview for what it’s like to participate in regenerative medicine and stem cell clinical trials from a patient perspective, and discusses our holistic, inter-disciplinary approach to healthcare. Hosted by Bobby Gordon. This episode was recorded on January 24, 2025 and information presented is current as of this date.
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    31 分
  • Holly Young, MSc, Cell Therapy Production at UC San Diego

    Holly Young, MSc, Cell Therapy Production at UC San Diego
    2025/08/08
    This episode features Holly Young, MSc, who serves as the facility director of the Advanced Cell Therapy Laboratory (ACTL), as part of the Sanford Advanced Therapy Center at UC San Diego. The mission of ACTL is to provide leading-edge services for the development and production of innovative cell therapy products, to support UC San Diego and other researchers in the transition from research and development to clinically relevant manufacturing of cell therapy products; to improve patient treatments. Learn more at actl.ucsd.edu. Hosted by Bobby Gordon. This episode was recorded on January 30, 2025 and information presented is current as of this date.
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    22 分
  • Dr Kenneth Savin, Redwire | Groundbreaking ISS Biotech Discoveries

    Dr Kenneth Savin, Redwire | Groundbreaking ISS Biotech Discoveries
    2025/08/04
    This episode features our conversation with Dr Kenneth A. Savin, Chief Scientist at Redwire. Dr. Savin was named to TIME’s “2025 TIME100 Health List of the 100 Most Influential People in Global Health.” We discuss his 20-plus year career and expertise in the pharmaceutical industry and his pioneering work accelerating cutting-edge space biotech research capabilities, leveraging microgravity to improve human health on Earth. At Redwire, Dr. Savin has overseen trailblazing investigations onboard the International Space Station (ISS) in partnership with NASA and the ISS National Laboratory. Redwire successfully bioprinted the first human knee meniscus and first live human cardiac tissue using its BioFabrication Facility on the ISS. These breakthroughs address challenges faced by millions of people worldwide through the application of organ transplantation and tissue therapy and advance the next generation of pharmaceutical therapies. Dr. Savin has coordinated groundbreaking protein crystallization investigations onboard the ISS with pharmaceutical companies like Eli Lilly and Company (Lilly) and Bristol Myers Squibb using Redwire’s in-space pharmaceutical lab, PIL-BOX, for improved drug development. These investigations have focused on various applications to address the world’s most prevalent conditions, including antiviral, antifungal, and antiseizure applications, heart disease, and bone loss. Hosted by Bobby Gordon. This episode was recorded on December 2, 2024, and information presented in this episode is current as of this date.
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    32 分
  • Dr. Catriona Jamieson | The Search for Cancer Cures in Outer Space

    Dr. Catriona Jamieson | The Search for Cancer Cures in Outer Space
    2025/06/25
    This episode’s conversation focuses on the innovative work of Dr. Catriona Jamieson, Director of the Sanford Stem Cell Institute at UC San Diego, and the Axiom-4 (Ax-4) launch. This space research mission includes the Institute’s testing of the efficacy of “rebecsnib” on tumor organoids derived from cancer stem cells of consenting patients with secondary acute myeloid leukemia, ovarian cancer, metastatic breast cancer and glioblastoma multiforme. The drug holds potential to fight 23 types of cancer — any that involve ADAR1 in their development and progression. The hope is that the investigational new drug prevents the miniature tumors from growing, as it did on Axiom Space’s previous Ax-3 mission, with cell line-derived triple negative breast cancer tumor organoids. Hosted by Bobby Gordon This episode was recorded on June 6, 2025, and information presented is accurate as of this date.
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    29 分
  • Stem Cells 101 with Dr. Sheldon Morris, UC San Diego

    Stem Cells 101 with Dr. Sheldon Morris, UC San Diego
    2025/06/16
    Our conversation with Dr. Sheldon Morris, M.D., MPH, includes an overview of stem cells and some of the basics of regenerative medicine. Our Stem Cells 101 episode provides listeners with high-level, foundational knowledge about research and therapeutic treatments, clinical trials and related work from Dr. Morris and his team at the UC San Diego Sanford Stem Cell Institute and the Sanford Stem Cell Clinical Center. Learn more at stemcells.ucsd.edu. Hosted by Bobby Gordon. This episode was recorded on April 7, 2025, and information presented is current as of the date of this recording.
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    22 分
  • Davide Marotta, Ph.D.: Science on the International Space Station

    Davide Marotta, Ph.D.: Science on the International Space Station
    2025/05/29
    The Sanford Stem Cell Institute’s Bobby Gordon sits down with Davide Marotta, Ph.D., program director of in-space biomanufacturing at the International Space Station National Laboratory (ISSNL), to discuss the innovative low-Earth orbit economy and the future of science in space. We also discuss ISSNL's collaborations with UC San Diego's Sanford Stem Cell Institute. Before joining the ISSNL in 2022, Dr. Marotta worked as a scientist at the New York Stem Cell Foundation, where his research focused on developing advanced models of neurodegenerative diseases using induced pluripotent stem cell (iPSC)-derived brain organoids and tracking the effects of microgravity on them. He received both bachelor’s and master’s of science degrees in biomedicine from the University of Palermo in Italy, and a Ph.D. in molecular and cell biology at University College London. He conducted post-doctoral research at the Institute of Cancer Research in London, where he worked on drug discovery and cancer evolution, and Columbia University in New York, where his research centered on hematopoietic stem cells and aging. Dr. Marotta is the author of the newly released book “ Published in April 2025, it explores the revolutionary impact of space on science, technology, and industry. Hosted by Bobby Gordon. This episode was recorded Oct. 15, 2024; information presented was current as of the date of recording.
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    35 分
  • Jessica Pham: Making Space-Based Cancer Research Possible

    Jessica Pham: Making Space-Based Cancer Research Possible
    2025/05/16
    Jessica Pham — manager of Dr. Catriona Jamieson’s lab at the University of California San Diego and Stellar Mission Specialist at its Sanford Stem Cell Institute — has successfully prepared seven research payloads for transport to the International Space Station. There, astronaut-scientists have used the tumor organoids she creates from the stem cells of consenting cancer patients to better understand, predict, and treat disease progression, in partnership with researchers on the ground. Host: Bobby Gordon This episode was recorded on October 18, 2024 and information presented is current as of the recording of this episode.
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    26 分
  • Dr. John Dick on Stem Cells & Blood Cancer

    Dr. John Dick on Stem Cells & Blood Cancer
    2025/05/02
    Our conversation explores the work of John E. Dick, Ph.D., FRS, senior scientist and cancer research chair at the Princess Margaret Cancer Centre and McEwen Centre for Regenerative Medicine, of the University Health Network; professor of molecular genetics at the University of Toronto; and co-leader of the Acute Leukemia Translational Research Initiative at the Ontario Institute for Cancer Research. Dick’s research focuses on the role of stem cells in the development of blood and blood cancer. In the mid-1990s, Dick was the first to identify cancer stem cells, transforming our views on the origin and nature of cancer. Because cancer stem cells survive conventional chemotherapy treatment and regenerate, his discovery has important implications for cancer therapy. Hosted by Bobby Gordon. This episode was recorded Oct. 17, 2024; information presented was current as of the date of recording.
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    38 分