Are your antidepressants leaving you feeling physically drained? In this episode, Joey DiMatteo (PharmD) leads an evidence-based discussion on how SSRIs often cause hidden nutrient deficiencies that can hinder your mental health progress and reduce the effectiveness of the antidepressants. We break down the research and science behind drug-induced nutrient depletion, the specific vitamins you are likely missing, and the professional-grade solutions to restore your well-being.

Additionally, Joey & Dante DiMatteo (PharmD) discuss the groundbreaking shift in pediatric guidelines: why early peanut introduction is the key to ending the peanut allergy epidemic. These new guidelines have already caused a 43% drop in childhood peanut allergies! Get the clarity you need from trusted medical experts who work on the front lines of pharmacy every day.

We love questions! Comment below or email us: questions@askjoedimatteo.com

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PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowYTM
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:31 - Show Intro
01:11 - SSRIs and Nutrients
02:33 - How do SSRIs work?
04:03 - The link with methylation
05:52 - The link with CoQ10
06:52 - What else is critical to overall wellbeing?
10:21 - Other vitamins and minerals that help
12:15 - Which supplements to take while on SSRIs
13:44 - Other things to check
14:20 - Potential drug interactions
22:32 - Peanut Allergies have plummeted in children
24:03 - More details about the study
26:31 - What is the IgE?
28:54 - Why have peanut allergies reduced?
32:08 - What are the new suggestions for peanut allergies?
35:39 - Show Outro

SHOW NOTES:
1) Folate in Depression (NIH) - https://tinyurl.com/2ka38bfa
2) Genes and SSRI-Associated Sexual Dysfunction (NIH) - https://tinyurl.com/4wpru9m2
3) Therapy for SSRI-Resistant Major Depression (NIH) - https://tinyurl.com/2w4a96uw
4) L-methylfolate for Major Depression (BMJ) - https://tinyurl.com/2wasv3dx
5) Guidelines for Early Food Introduction and Allergy (AAP) - https://tinyurl.com/4suncxjc
6) Peanut Allergy Rates Dropped (Article) - https://tinyurl.com/ynct84vv

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

In this episode, we are diving into a topic that—quite literally—gets people's blood pumping! We are looking at the brand new, 2025 American Heart Association and American College of Cardiology Hypertension Guidelines (AKA The PREVENT Standard), and to help us decode this massive document, we've got Dante DiMatteo (PharmD) in the hot seat.

The medical community is calling this a "watershed moment." We're moving from just looking at a number on a cuff to understanding the whole system—heart, kidneys, and metabolism. So what changed? What does it mean for you and your health? Generation Health explains it all!

We love questions! Comment below or email us: questions@askjoedimatteo.com

ALL PRODUCTS: https://www.AskJoeDimatteo.com

CONNECT:
Products - https://askjoedimatteo.com/youtube
Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowYTM
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:24 - Show Intro
01:22 - New Blood Pressure Guidelines
02:43 - What has been updated?
04:59 - How is kidney function related to blood pressure?
06:44 - Mechanisms of blood pressure and cognitive decline
08:58 - What are healthy blood pressure readings?
10:08 - How is someone diagnosed for high BP?
15:22 - What has changed?
19:44 - Changes to pharmacology
25:04 - Other pharmacology changes
26:28 - Changes to lifestyle modifications
32:23 - Show Outro

SHOW NOTES:
1) 2025 Guideline For High Blood Pressure in Adults (JACC Journals) - https://tinyurl.com/2hudprv5
2) Updated Hypertension Guidelines (Pharmacy Times) - https://tinyurl.com/mrxn7tkt
3) About PREVENT Risk Calculator (AHA) - https://tinyurl.com/mspjtyh2
4) PREVENT Online Calculator (heart.org) - https://tinyurl.com/3f7wxz6r

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

Lithium appears to contribute to cognitive preservation during aging and a new study looks at what happens to the brain when lithium is deficient, possibly leading to Alzheimer's disease. Better still, it looks like increasing the brain's lithium levels may actually reverse the effects. Lithium orotate is getting a glow-up and we're excited for it!

Also, the "magic pill" may finally be real. Wegovy, one of the popular new GLP-1 weight-loss medications is now available as a daily oral prescription! How does it differ from injections and how is dosing affected? Is it cheaper than the shots?

We love questions! Comment below or email us: questions@askjoedimatteo.com

ALL PRODUCTS: https://www.AskJoeDimatteo.com

CONNECT:
Products - https://askjoedimatteo.com/youtube
Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowYTM
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:29 - Show Intro
01:38 - Study: Alzheimer's and Lithium Deficiency
02:52 - What is Lithium?
04:26 - What was studied?
06:47 - Details about the animal study
08:55 - How is lithium protecting the brain?
12:22 - Lithium in drinking water
13:28 - Takeaways
16:21 - Wegovy Pill
17:31 - Details of the Wegovy Pill
19:45 - Do you need to titrate up?
20:36 - If it's working, do you need to take more?
22:49 - What's the difference between the pill and injectable?
23:59 - Differences in cost
25:13 - Other points
27:43 - Dietary suggestions while on Wegovy
29:54 - Show outro

SHOW NOTES:
1) Lithium and Alzheimer's (Nature) - https://tinyurl.com/aywhpx2h
2) Lithium deficiency and onset of Alzheimers (NIH) - https://tinyurl.com/y2dxvmdf
3) New GLP-1 Pill Compared to Shot (Web MD) - https://tinyurl.com/mt2mvtpv
4) Wegovy Pill in High Demand (NBC News) - https://tinyurl.com/ktb84h54
5) Wegovy pill now available across America (PR Newswire) - https://tinyurl.com/2t6uda9w

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.