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How could a relatively simple chemical code give rise to the complexity of a human being? How could our human genome have evolved? And how does it actually work? Your genome defines you at the most profound level. That same genome is present in every one of the approximately 100,000 billion cells that make you who you are as an individual member of the human species. An important ingredient of the genome, and its essential nature, is memory .

Obesity, autism, mental health problems, IBS, allergies, auto-immunity, cancer. Does the answer to the modern epidemic of ‘Western’ diseases lie in our gut? You are 10% human. For every one of your cells, there are nine impostors hitching a ride. You are not just flesh and bone, but also...

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks listeners through the astonishing and controversial process of de-extinction.

A sweeping, paradigm-shifting account of how evolution is no longer driven just by nature but also by human choices Why are conditions like autism, asthma, obesity, and allergies exploding at unprecedented rates? Why are we living longer, getting smarter, having far fewer kids? If Darwin was...

Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?

DNA serves as the basic instruction manual for life. In this installment, we look at the way in which DNA is structured, replicated, and how it is packaged into such a small area. This will provide the basic understanding of how genes are structured in an easy to understand way.

*** Shortlisted for William Hill Sports Book of the Year 2013 *** Is Usain Bolt a superhuman one-off? Are sports stars like Paula Radcliffe and Tiger Woods born or made? Could we all be Olympians if we trained hard enough? And is the answer to be found by looking at Alaskan huskies? In this...

In Faster, Higher, Stronger, veteran journalist Mark McClusky brings listeners behind the scenes with a new generation of athletes, coaches, and scientists whose accomplishments are changing our understanding of human physical achievement and completely redefining the limits of the human body.

A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.

In Arrival of the Fittest, renowned evolutionary biologist Andreas Wagner draws on over 15 years of research to present the missing piece in Darwin's theory. Using experimental and computational technologies that were heretofore unimagined, he has found that adaptations are not just driven by chance, but by a set of laws that allow nature to discover new molecules and mechanisms in a fraction of the time that random variation would take.

Sind es nur die Gene, die unser Wesen bestimmen? Welche Rolle spielen dabei Erfahrungen, Erlebnisse und das, was wir "Seele" nennen? Das Wechselspiel zwischen Erbanlagen und Lebensumständen beschäftigt die moderne Medizin bis heute. Joachim Bauer macht dieses Zusammenwirken von Geist und Genen erstmals populär verständlich - und setzt sich ein für einen bewussteren Umgang mit der menschlichen Seele.

Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story Fewer ideas have been more toxic or harmful than the idea of the biological reality of race, and with it the idea that humans of different races...

In 2010, scientists led by J. Craig Venter became the first to successfully create "synthetic life" - putting humankind at the threshold of the most important and exciting phase of biological research, one that will enable us to actually write the genetic code for designing new species to help us adapt and evolve for long-term survival. The science of synthetic genomics will have a profound impact on human existence, including chemical and energy generation, health, clean water and food production, environmental control, and possibly even our evolution.

In Food, Genes, and Culture, renowned ethnobotanist Gary Nabhan shows why the perfect diet for one person could be disastrous for another. If your ancestors were herders in Northern Europe, milk might well provide you with important nutrients, whereas if you’re Native American, you have a higher likelihood of lactose intolerance. If your roots lie in the Greek islands, the acclaimed Mediterranean diet might save your heart; if not, all that olive oil could just give you stomach cramps.

A vibrant young Hispano woman, Shonnie Medina, inherits a breast-cancer mutation known as BRCA1.185delAG. It is a genetic variant characteristic of Jews. The Medinas knew they were descended from Native Americans and Spanish Catholics, but they did not know that they had Jewish ancestry as well. The mutation most likely sprang from Sephardic Jews hounded by the Spanish Inquisition. The discovery of the gene leads to a fascinating investigation of cultural history and modern genetics by Dr. Harry Ostrer and other experts on the DNA of Jewish populations.

L'opera che proponiamo all'ascolto è fondamentale - secondo l'autorevole rivista "Science" - per chi vuole cominciare a capire il rapporto fra il nostro patrimonio genetico e la storia delle civiltà. Come e da dove ebbero origine le diverse popolazioni umane? Quali percorsi seguirono via via che si distribuivano nei vari continenti, si differenziavano fra loro e si moltiplicavano? Che ruolo ha avuto l'evoluzione culturale e tecnologica? Quali e quante lingue sono parlate al mondo? Esistono veramente le 'razze' umane? A queste, e a molte altre domande, affascinanti e grandiose, offre una risposta un'opera che fin dalla sua prima pubblicazione in USA nel 1994 (la versione italiana è di Adelphi, 1997) è stata definita un caposaldo della ricerca.

The burgeoning new science of epigenetics offers a cornucopia of insights - some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.

While we joke that men are from Mars and women are from Venus, our gender differences can't compare to those of other animals. For instance: the male garden spider spontaneously dies after mating with a female more than fifty times his size. Female cichlids must guard their eggs and larvae--even from the hungry appetites of their own partners. And male blanket octopuses employ a copulatory arm longer than their own bodies to mate with females that outweigh them by four orders of magnitude. Why do these gender gulfs exist?

What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells, and whole organisms to create new ones that could never have previously existed on their own.

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).