検索キーワード： 遺伝学

Most people know that Gregor Mendel, the Moravian monk who patiently grew his peas in a monastery garden, shaped our understanding of inheritance. But people might not know that Mendel's work was ignored in his own lifetime, even though it contained answers to the most pressing questions raised by Charles Darwin's revolutionary book, On Origrin of the Species, published only a few years earlier. Mendel's single chance of recognition failed utterly, and he died a lonely and disappointed man.

One in 3,000 people is born with neurofibromatosis. It affects all of them in different ways. For some, neurofibromatosis is as clear as the tumors on their face. For others, it hides beneath the surface, creating tumors that destroy hearing, vision, and more. Many of them are misdiagnosed, misunderstood, and often simply missed by a world of medicine that doesn't have a full grasp on all the effects of NF.

In this fascinating exploration, geneticist Bryan Sykes turns his sights on the United States, one of the most genetically variegated countries in the world. From the blue-blooded pockets of old-WASP New England to the vast tribal lands of the Navajo, Bryan Sykes takes us on a historical genetic tour, interviewing genealogists, geneticists, anthropologists, and everyday Americans with compelling ancestral stories.

From New York Times best-selling author Sam Kean come more incredible stories of science, history, language, and music, as told by our own DNA. There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking.

Having worked on numerous high-profile genetic investigations, including one focused on the famed Iceman of the Italian Alps, Bryan Sykes has become a premier authority on human genetics. In DNA USA, Sykes examines the unique fabric of the population of the United States - one of the world’s most genetically variegated countries. His fascinating discoveries offer new insights into the biological profile of the great melting pot.

Until very recently, if you were to ask most doctors, they would tell you there were only two kinds of medicine: the quack kind, and the evidence-based kind. The former is baseless, and the latter based on the best information human effort could buy. Well, Eric Topol isn't most doctors, and he suggests you entertain the notion of a third kind of medicine, one that will make the evidence-based state-of-the-art stuff look scarcely better than an alchemist trying to animate a homunculus in a jar.

Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species.

Human beings have astonishing genetic vulnerabilities. More than half of us will die from complex diseases that trace directly to those vulnerabilities, and the modern world we've created places us at unprecedented risk from them. In It Takes a Genome, Greg Gibson posits a revolutionary new hypothesis: Our genome is out of equilibrium, both with itself and its environment. Simply put, our genes aren't coping well with modern culture.

Understanding the basis of making moral choices is crucial as society becomes increasingly complex. Moral Choices: An Introduction to Ethics gives college students a solid grounding in both theory of ethics and its applications to the social issues of today. Avoiding undue dogmatism, Professor Scott B. Rae outlines the distinctive elements of Christian ethics.

By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science, which will revolutionize medicine and change the way we think about and treat disease.

A leading brain scientist's look at the neurobiology of pleasure-and how pleasures can become addictions. Whether eating, taking drugs, engaging in sex, or doing good deeds, the pursuit of pleasure is a central drive of the human animal. In The Compass of Pleasure Johns Hopkins neuroscientist David J. Linden explains how pleasure affects us at the most fundamental level: in our brain.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

Despite extensive evidence highlighting the influence of genetics in the business world, this critical connection has been glossed over by corporate leaders and management gurus. Now, for the first time, author Scott Shane explains why genes matter, and how an understanding of their relationship to behavior is of vital importance to employers, employees, and policy makers.

Already technology enables parents to select some genetic traits for their children, and soon it will be possible to begin to shape ourselves as a species. Countering loud cries of alarm, bioethics expert Ronald Green explains why our fears about genetic engineering are overblown and how we can move forward responsibly to create a better future.

A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.

In Strange Bedfellows, David P. Barash and Judith Eve Lipton look at how biology actually promotes monogamy in some species and how these lessons apply to human beings. An accessible work of science that is relevant to our intimate daily life, Strange Bedfellows will reassure some people, surprise others, and engage everyone.

For over a century, opening the black box of embryonic development was the holy grail of biology. Evo Devo--Evolutionary Developmental Biology--is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

If we are, in part, a product of our genes, can free will exist? Incisive and engaging, this indispensable tour of evolutionary biology runs the gamut of contemporary debates, from science and religion to our place in the universe.

Two Nobel Laureates discuss the genome and more. James D. Watson changed the course of history with his discovery of DNA, the "secret of life". Watson is the recipient of the Presidential Medal of Freedom, the National Medal of Science, and, with Francis Crick and Maurice Wilkins, the 1962 Nobel Prize in Physiology or Medicine.