検索キーワード： 生物学

In September 2016, a woman in Nevada became the first known case in the US of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions.

In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth merchant, Antonie van Leeuwenhoek, look down their handmade microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences and altering both forever. It is the fact that complex living organisms are assemblages of tiny self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christens them 'cells'.

The Earth teems with life: in its oceans, forests, skies, and cities. Yet there's a black hole at the heart of biology. We do not know why complex life is the way it is, or, for that matter, how life first began. In The Vital Question, award-winning author and biochemist Nick Lane radically reframes evolutionary history, putting forward a solution to conundrums that have puzzled generations of scientists.

Physiology is the science of life, and sets out to understand how living things work and what makes them distinct from the non-living. It considers how our bodies are supplied with energy, how they maintain their internal parameters, the ways in which we gather and process information, the ways we take action, and the creation of new generations.

Your body has trillions of cells, and each one has the complexity and dynamism of a city. Your life, your thoughts, your diseases, and your health are all the function of cells. But what do you really know about what goes on inside you? The Cell: Inside the Microscopic World That Determines Our Health, Our Consciousness, and Our Future is a fascinating story of the incredible complexity and dynamism inside the cell and of the fantastic advancements in our understanding of this microscopic world.

Charles Darwin’s theory of evolution now forms the basis for all the life sciences, but it ignited widespread controversy upon its 1859 publication. The idea that humans and animals might have evolved from a common source came as a shock to readers at the time, and people struggle with the implications of Darwin’s theory to this day. But Darwin foresaw this resistance and argued his case with extensive examples and rigorous logic - and his theory continues to push us toward a deeper understanding of life on Earth. 

A deft mixture of memoir and history, modern biology and behavior, In Search of Memory brings listeners from Kandel's childhood in Nazi-occupied Vienna to the forefront of one of the great scientific endeavors of the 20th century: the search for the biological basis of memory. Nobel Prize winner Eric R. Kandel intertwines the intellectual history of the powerful new science of the mind - a combination of cognitive psychology, neuroscience, and molecular biology - with his own personal quest to understand memory.

A riveting exploration of how microbes are transforming the way we see nature and ourselves - and could revolutionize agriculture and medicine. Prepare to set aside what you think you know about yourself and microbes. Good health - for people and for plants - depends on Earth's smallest creatures. The Hidden Half of Nature tells the story of our tangled relationship with microbes and their potential to revolutionize agriculture and medicine, from garden to gut.

Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in Egypt when Tom came down with a stomach bug. What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.

The knowledge of death is so terrifying that we live most of our lives in denial of it. Our fear of death has underpinned our religions, inspired our cultures, and also driven our science. Today we are living through a revolution in biology. Giant strides are being made in our understanding of why we age and die, and why some species live longer than others. Immortality, once a faint hope, has never been more within our grasp. Here, Nobel Prize-winning biologist Venki Ramakrishnan offers a definitive look at why we die - and whether we can do anything about it.

Humans have kept honey bees in hives for millennia, yet only in recent decades have biologists begun to investigate how these industrious insects live in the wild. The Lives of Bees is Thomas Seeley’s captivating story of what scientists are learning about the behavior, social life, and survival strategies of honey bees living outside the beekeeper’s hive - and how wild honey bees may hold the key to reversing the alarming die-off of the planet’s managed honey bee populations.

Carl Zimmer investigates one of the biggest questions of all: what is life? The answer seems obvious until you try to seriously answer it. Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can’t answer that question here on Earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society’s most charged conflicts - whether a fertilised egg is a living person, for example, and when we ought to declare a person legally dead. 

In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field is horizontal gene transfer (HGT), or the movement of genes across species lines. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT. In The Tangled Tree David Quammen chronicles these discoveries through the lives of the researchers who made them.

If you think sexism thrives only on Wall Street or Hollywood, you haven’t visited a lab, a science department, a research foundation, or a biotech firm. Rita Colwell is one of the top scientists in America: the groundbreaking microbiologist who discovered how cholera survives between epidemics and the former head of the National Science Foundation. But when she first applied for a graduate fellowship in bacteriology, she was told, “We don’t waste fellowships on women.” A lack of support from some male superiors would lead her to change her area of study six times.

Since the dawn of recorded history, humans have felt a kinship with the sleek and beautiful dolphin, an animal whose playfulness, sociability, and intelligence seem like an aquatic mirror of mankind. In recent decades, we have learned that dolphins recognize themselves in reflections, count, grieve, adorn themselves, feel despondent, rescue one another (and humans), deduce, infer, seduce, form cliques, throw tantrums, and call themselves by name. 

The immune system holds the key to human health. In The Beautiful Cure, leading immunologist Professor Daniel Davis describes the scientific quest to understand how it works - and how it is affected by stress, sleep, age and our state of mind - and explains how this knowledge is now unlocking a revolutionary new approach to medicine and well-being.

Written by professor of cognitive neuroscience at UCL Sophie Scott and composed of 10 mind-blowing yet accessible essays, The Brain guides you through the astounding complexities of the organ that makes you, you. From diving into the networks of neurons that are vital to our functioning, to the way our brains differ from one another and how neuroscience is shaping up for the future, this book is a guide to our most powerful and awe-inspiring body part.

The knowledge of death is so terrifying that we live most of our lives in denial of it. One of the most difficult moments of childhood must be when each of us first realizes that not only we but all our loved ones will die—and there is nothing we can do about it. Or at least, there hasn’t been. Today, we are living through a revolution in biology. Giant strides are being made in understanding why we age—and why some species live longer than others. Could we eventually cheat disease and death and live for a very long time, possibly many times our current lifespan?

The question of how and why organisms age has teased scientists for centuries. There are myriad competing theories, from the idea that ageing is a simple wear and tear process, like the rusting of a car, to the belief that ageing and death are genetically programmed and controlled. In fact, there is no clearly defined limit to life and no single, predictable program playing itself out: different things are happening within and between tissues, and each system or organ accumulates damage at its own pace, according to the kind of insults imposed on it by daily living. 

First published in the 19th century, On the Origin of Species is one of the most important and controversial books ever written on human origins. Darwin's work is the cornerstone of the theory of evolution and is as important today as it was when it was released nearly 160 years ago.