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In the South, you always say “yes, ma’am” and “no, ma’am.” You know everybody’s business. Football is a lifestyle, not a pastime. Food — especially dessert — is almost a religious experience. And you protect your friends as fiercely as you protect your family — even if the threat is something you cannot see.

What would you do if you knew your life's potential? That's the question facing the residents of Deerfield, Louisiana, when the DNAMIX machine appears in their local grocery store. It's nothing to look at, really—it resembles a plain photo booth. But its promise is amazing: With just a quick swab of your cheek and two dollars, the device claims to use the science of DNA to tell you your life's potential. With enough credibility to make the townspeople curious, soon the former teachers, nurses, and shopkeepers of Deerfield are abruptly changing course to pursue their destinies.

The envy of all her friends, wife and mother Saphora Warren is the model of Southern gentility and accomplishment. She lives in a beautiful Lake Norman home, and has raised three capable adult children. Her husband is a successful plastic surgeon - and a philanderer. It is for that reason that, after hosting a garden party for Southern Living magazine, Saphora packs her bags to escape the trappings of her picturesque-but-vacant life.

As a child Gifty would ask her parents to tell the story of their journey from Ghana to Alabama, seeking escape in myths of heroism and romance. When her father and brother succumb to the hard reality of immigrant life in the American South, their family of four becomes two - and the life Gifty dreamed of slips away. Years later, desperate to understand the opioid addiction that destroyed her brother's life, she turns to science for answers. But when her mother comes to stay, Gifty soon learns that the roots of their tangled traumas reach farther than she ever thought.

Macey and Ben Samuelson have much to be thankful for: great friends, a beautiful - if high-maintenance - Victorian house on idyllic Tybee Island, and a rock-solid marriage. The only thing missing is what they want the most. After her fifth miscarriage in six years, Macey worries that the family they’ve always dreamed of might be out of reach. Her sister suggests adoption, but Macey and Ben aren’t interested in pursuing that path...until a three-legged Golden Retriever named Keeper wags his way into their home and their hearts.

Sylvie Snow knows the pressures of expectations: a woman is supposed to work hard, but never be tired; age gracefully, but always be beautiful; fix the family problems, but always be carefree. Sylvie does the grocery shopping, the laundry, the scheduling, the schlepping, and the PTA-ing, while planning her son’s Bar Mitzvah and cheerfully tending her husband, Paul, who’s been lying on the sofa with a broken ankle.

Caroline Venable has everything her Southern heritage promised: money, prestige, a powerful husband - and a predictable routine of country-club luncheons, cocktail parties, and dinners hosting her husband's wealthy friends, clients, and associates in his successful land-developing conglomerate. To escape her stifling routine, Caro drinks a little too much. But her true solace is the Lowcountry island her beloved Granddaddy left her - an oasis of breathtaking beauty that is home to a band of wild ponies.

With clouds looming ominously on the horizon, a group of children play among the roots of the gnarled Bone Tree. Their games will be interrupted by a merciless storm – bringing with it the Great Flood of 1927 - but not before Robert Chatham shares his first kiss with the beautiful young Dora. The flood destroys their homes, disperses their families, and wrecks their innocence. But for Robert, a boy whose family has already survived unspeakable pain, that single kiss will sustain him for years to come.

At 12, Emily Parmenter is left mostly to herself after her mother disappears and her beloved older brother dies. Emily has built a life around the faded plantation where her remote father and hunting-obsessed brothers raise hunting spaniels. It is a meager, masculine world, but to Emily it has magic. And then comes Lulu Foxworth, troubled daughter of a truly grand plantation, who has run away from her hectic Charleston debutante season.

At 12, Peyton McKenzie isn't ready to share her widowed father with anyone, let alone Nora, her redheaded, cigarette-smoking cousin who just rolled into town behind the wheel of a pink Thunderbird. But her father seems to like Nora, and she does make for good conversation with her friends at the Losers Club, and prim Aunt Augusta hates her, which means she can't be all bad. In fact, maybe Nora is just what quiet Lytton, Georgia, needs this summer.

After an airless childhood in Savannah, Smoky O'Donnell arrives in Atlanta, dazzled and chastened by this hectic young city on the rise. Her new job as a writer with the city's Downtown magazine introduces her to many unforgettable people and propels her into the center of momentous events that will irrevocably alter her heart, her career, and her world.

The pale-skinned, black-eyed baby is a bad omen. That’s one thing the people on the old plantation are sure of. The other is that Miss Rue - midwife, healer, crafter of curses - will know what to do. But for once Rue doesn’t know. Times have changed since her mother, Miss May Belle, held the power to influence the life and death of her fellow slaves. Freedom has come. The master’s Big House lies in ruins. But this new world brings new dangers, and Rue’s old magic may be no match for them.

No one knows why Dixie’s son is standing there, on Christmas Day, no less. And he doesn’t look happy. Dixie is keeping a big secret that will shake up everyone around her. Julie’s daughter, Colleen, is coming home for a visit, but she’s not alone. Janine makes a new friend, but nobody is thrilled about it. Julie and Dawson question their budding relationship. Will they move forward or decide that being friends is the best way to go? There’s so much happening on this little island, including the return of Julie’s ex husband and a shocking surprise at the end.

When Meg shows up at her mother's door, she has no idea how to break the news to her. She's come home from France, pregnant. At just nineteen years old, this wasn't where she saw her life going. Now, trying to hide her growing belly and figure out her next decision, she moves in with her mother, sister and aunt on Seabreeze Island. But, how long can she keep her pregnancy a secret, and what happens if another surprising person shows up at the front door of Julie's house?

She’s 43 years old…and starting over from scratch. How did this happen? She had it all together. A stable marriage of two decades. Two grown daughters. And now she and her husband, empty nesters, were moving to a beach house. Until he showed up late one night and tore their marriage apart. A secret life. A different woman. Another family. Left alone, she has to begin again. And then her estranged sister and mother get thrown into the mix. When she buys a house on a small South Carolina island, will she learn what life is really about?

Dixie has a boyfriend, and she's hiding him from everybody. William gets a job offer and has a big decision to make. Dawson has a huge announcement. Colleen gets the shock of her life. Julie adjusts to being a grandmother. Meg and Christian start building a life together. Someone unexpected comes to town and decides not to leave.

For fourteen-year-old Leah Payne, life in her beloved coastal Carolina town is worlds away from the harsh realities of the day. Loyal to her lumberjack father, she knows only of the familiarity of her small community, the magic of the natural world, and the creative intuition that prompts her to march to the beat of her own drum. But when an accident takes her father's life, leaving her an orphan, Leah finds herself cast into a family of strangers whose welcoming façade hides a terrible secret.

With mysterious serial murders putting peaceful Lexington, Alabama, on edge, Jessie and Hubert Wiggins’ steadfast calm and devotion to each other reassures everyone that faith will see them through. But Jessie and Hubert have paid a terrible hidden cost to maintain their devout facade and respectable standing. Nothing can allay the guilt they feel—or stop the growing distrust between them.

It’s a stormy summer day when Ottawa coroner Dr. Cate Spencer is called to the scene of an alleged suicide. Inside a narrow vault in the Dominion Archives’ nitrate film storage facility—kept separate from the rest of the collection due to its dangerous combustibility—officers pressure her to rule the death a suicide. When parts of the scene don’t add up and a deliberately set spark threatens her life, she suspects that this death might be a murder.

Charlie Garner has a bad feeling. His ex-wife, Meg, has been missing for over a week and one quick peek into her home shows all her possessions packed up in boxes. Neighbors claim she’s running from bill collectors, but Charlie suspects something more sinister is afoot. Meg was last seen working at the local donut shop, a business run by a shadow group most refer to as ‘The Saucer People’; a space-age, evangelist cult who believe their compound to be the site of an extraterrestrial Second Coming.