検索キーワード： 遺伝子

19世紀後半にメンデルが発見した遺伝の法則とダーウィンの進化論が出会い、遺伝学は歩み始めた。そして今、人類はゲノム編集の時代を迎えている。遺伝子が握る人類の運命とは？　ピュリッツァー賞受賞の医学者が自らの家系に潜む精神疾患の悲劇を織り交ぜながら、圧倒的なストーリーテリングで紡ぐ遺伝子全史

2000年代初頭、人間の全遺伝情報=ヒトゲノムがついに解読された。その後まもなく、山中伸弥らがiPS細胞(人工多能性幹細胞)の作製に成功。そして今、ジェニファー・ダウドナらが開発した新技術「CRISPR-Cas9」により、人類は「ゲノム編集」の時代を迎えている。自らの設計図を望み通りに書き換えられるようになったとき、人間の条件はどう変わるのか? 科学と倫理のせめぎ合いを圧倒的なストーリーテリングで描く傑作。

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

From an acclaimed Harvard professor and one of Time’s most influential people, this paradigm-shifting audiobook shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls listeners to consider a future where aging can be treated.

Renowned regenerative and restorative sports-medicine doctor Guarav Goswami, MD, provides advanced, minimally invasive (non-surgical) treatments to help his patients get back to peak performance levels - no matter their age. Harnessing the transformative power of stem cells is central to his expertise. In fact, stem cell therapy is proven to be effective in the treatment of many common conditions from arthritis and back pain to Alzheimer’s, Parkinson’s, and cancer. This book is an accessible and informative introduction to the amazing powers of stem cell therapy.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

Contrary to conventional wisdom, chronic disease is not genetically predetermined but results from a mismatch between our genes and environment and lifestyle. What we call a "disease" is the outcome of an imbalance in one or more of the seven core physiological processes. Leveraging a lifetime on the cutting edge of research and practice, Dr. Jeffrey S. Bland lays out a road map for good health by helping us understand these processes and the root causes of chronic illness.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

Nur sechs Tage nach der Geburt ihrer Tochter Leni merken Vanessa und Markus, dass etwas nicht stimmt. Sie alarmieren den Notarzt. Es folgt eine beunruhigende Odyssee aus Krankenhausaufenthalten, Untersuchungen und schlaflosen Nächten - und dem Ausblick auf Operationen, die schwerwiegende Konsequenzen für Leni haben. Durch Höhen und Tiefen halten die Eltern zusammen, stützen sich auf Ärzt*innen und den Fortschritt der Medizin. Ein Mutmacher-Hörbuch über Hoffnung, Resilienz und den Wert der Familie.

How is it that a baboon and a blob of slime mould instinctively know what to eat for optimal health, balancing their protein, fat and carb intake in perfect proportions? In new, groundbreaking research that is transforming our understanding of nutrition, animals from locusts to lions and yes, humans too, demonstrate the remarkable science behind appetite.

The body is magnificent but it doesn't come with a lifetime warranty or an operating manual. You're the result of millions of years of evolution, but many of the adaptations that helped your ancestors survive are now working overtime to accelerate the aging process. The assumption here is that we are our genes and therefore trapped by the past. The good news is that your genetic code - the DNA sequence that is the biochemical basis of heredity - can play a minor role in the way you age.

Are you struggling with the relentless itchiness, irritation, and discomfort caused by eczema or psoriasis? Discover how coconut oil, a natural and effective remedy, can help soothe and manage these chronic skin conditions. In Coconut Oil for Eczema and Psoriasis: Soothe Irritation and Manage Symptoms Effectively, you’ll learn how to use this powerful oil to alleviate symptoms, protect the skin barrier, and prevent flare-ups.

Mastering Diabetes Management: The Ultimate Guide to Controlling Diabetes with Nutrition, Exercise, and Lifestyle Changes is an essential resource for anyone looking to effectively manage their diabetes. This comprehensive guide combines evidence-based strategies with practical advice to help listeners take charge of their health. From understanding how food impacts blood sugar to designing a personalized fitness routine, this book provides actionable steps for achieving balance and preventing complications.

In an age of groundbreaking scientific discovery, RNA Vaccines: A New Frontier in Science takes listeners on an illuminating journey through one of the most transformative innovations in modern medicine. From the frontlines of the COVID-19 pandemic to the promise of personalized therapies, RNA vaccines have reshaped our understanding of immunology, biotechnology, and global health.

If you or someone you love has Retinitis Pigmentosa (RP), the genetic condition that is passed down from one generation to the next, please keep reading. RP is not funny as it can be the cause of loss of vision, either in adults or children. Its effect on vision can be slow-moving or it can progress very quickly. The author has been affected for over 30 years and understands the emotional toll this condition can have on the newly diagnosed.

A coming-of-age memoir for modern times, Bleeder is the incredibly compelling tale of author Shelby Smoak. A hemophiliac, Smoak discovered he had been infected with HIV during a blood transfusion at the start of his college career. This devastating and destabilizing news led Smoak to see his world from an entirely new perspective, one in which life-threatening illness was perpetually just around the corner. Set in the 1990s along the North Carolina coast, Bleeder traces Smoak’s quest for love in a world that feels increasingly dangerous.

A new gene editing technology, invented just seven years ago, has turned humanity into gods. Enabling us to manipulate the genes in virtually any organism with exquisite precision, CRISPR has given scientists a degree of control that was undreamt of even in science fiction. But CRISPR is just the latest, giant leap in a long journey to master genetics. The Genetic Age shows the astonishing, world-changing potential of the new genetics and the possible threats it poses, sifting between fantasy and the reality when it comes to both benefits and dangers.

A tiny mutation on the X chromosome can shape a family’s history. Passed down from a “carrier” parent to a child, fragile X syndrome is the most common inherited cause of intellectual disability and autism. Beyond that—and a rarity among genetic disorders—some fragile X carriers not only transmit the mutation, but also experience related conditions themselves.

The field of biotechnology has evolved over the past four decades, developing medicines which are curing diseases. But this journey of success has been tough and arduous, built upon the shoulders of major failures.

In 2018, the first genetically modified babies were reportedly born in China, made possible by the invention of CRISPR technology in 2012. This controversial advancement overturned the preexisting moral consensus, which had held for over 50 years before: While gene editing an adult person was morally acceptable, modifying babies, and thus subsequent generations, crossed a significant moral line. John H. Evans here provides a meta-level guide to how these debates move forward and their significance to society.

Since 2010, it has been possible to determine a person's genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents "eliminate preventable genetic disease". As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices.

Una piccola sigla, un mondo di significati: il DNA è una risorsa contro le malattie, uno strumento per identificare gli assassini e una chiave per comprendere il comportamento umano. La sua storia è talmente antica da intrecciarsi con quella della comparsa della vita sulla Terra. E in futuro? Proviamo a parlarne direttamente con lui. Dalla genetica di Neandertal alla clonazione di esseri umani, metteremo a fuoco speranze (e timori) che grazie al DNA si aprono per la scienza e per le nostre esistenze.

In the book Diet and Health, I explained what brought us to our current state of 40 percent obesity in the Western world. My goal is to prevent type 2 diabetes, and to do that, I have to prevent obesity. I compared our historical diet to the modern Western diet, and showed how the modern diet has induced insulin resistance. I offered treatment for those who are obese or have pre-diabetes. I then described the various maintenance diets. If you already have type 2 diabetes, I can help you control it.

"Egoístas, inmortales y viajeras" explora el pasado, la realidad actual y el futuro de una enfermedad que, en términos estrictos, no es una única entidad sino más de doscientas distintas, tantas como tipos celulares construyen los diferentes órganos y tejidos de nuestro cuerpo. Discutiremos en primer lugar el origen del cáncer, una cuestión que hasta una fecha reciente no tuvo una respuesta concreta y de la que hoy podemos decir que es una enfermedad de los genes en el planeta de los genes.

Charlotte Raven had never heard of Huntington's disease when, in her mid-30s, she discovered that her father was suffering from the illness. Life for her and her young family would never be the same again. Patient 1 is her brutally candid account of coming to terms with this inherited neurodegenerative disease, which can manifest at any time in life for people who carry the faulty gene.

Ancestor Trouble is one writer’s attempt to use genealogy - a once-niche hobby that has grown into a multi-billion-dollar industry - to expose the secrets and contradictions of her own ancestors, and to argue for the transformational possibilities that reckoning with our ancestors offers all of us.

The science of epigenetics has been scientifically proven to give anyone the power to change the expressions of their genes. Genes can be altered by either the external environmental or internal mental and emotional signals without altering the gene sequence itself. The protocols in this book take a person through the step-by-step process of doing it. By using the detailed processes given, anyone can send new signals to their genes to produce and manufacture the different proteins to restore health, gain new strength, and extend life expectancy.

« Biologie des croyances » est une œuvre révolutionnaire dans le domaine de la nouvelle biologie. Chercheur et ex-professeur d'une école de médecine, Bruce H. Lipton, Phd., présente ses expériences et celles d'autres scientifiques de pointe qui ont examiné en détail les mécanismes par lesquels les cellules reçoivent et traitent les informations. Les implications de ces recherches changent radicalement notre compréhension de la vie en démontrant que les gènes et l'ADN ne contrôlent pas notre fonctionnement biologique.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....