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For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.

Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.

What makes the modern world work? The answer to this deceptively simple question lies in four "grand transitions" of civilization - in populations, agriculture, energy, and economics - that have transformed the way we live.

With well over 200 episodes and a dozen seasons, The Big Bang Theory is one of America's favorite television series, bringing a new class of character to mainstream television: the science nerd. In spite of its evident popularity and influence in shaping public attitudes to science and scientists, there are relatively few books that explore the show's culture and social dimension. The Science of The Big Bang Theory looks behind the comedy scenes and scripts of this long-running and successful TV show.

The universal appeal of Laura Ingalls Wilder springs from a life lived in partnership with the land, on farms she and her family settled across the Northeast and Midwest. In this revealing exploration of Wilder's deep connection with the natural world, Marta McDowell follows the wagon trail of the beloved Little House series. You'll learn details about Wilder's life and inspirations, pinpoint the Ingalls and Wilder homestead claims on authentic archival maps, and learn to grow the plants and vegetables featured in the series. Excerpts from Wilder's books, letters, and diaries bring to light her profound appreciation for the landscapes at the heart of her world.

In this Very Short Introduction, Warwick Vincent outlines the essential features of lake environments and their biology, offering an up-to-date view of lake ecosystems. Vincent traces the origins of lake science (limnology) from the seminal work of Francois Forel on Lake Geneva at the edge of the Swiss Alps, to modern approaches such as environmental sensors, satellite observations, stable isotope analysis, and DNA-based technologies which are used to probe the microbial life support systems that lead from sunlight to fish.

As Carl Sagan did for astronomy and Brian Green did for cosmology, Walter Lewin takes listeners on a marvelous journey in For the Love of Physics, opening our eyes as never before to the amazing beauty and power with which physics can reveal the hidden workings of the world all around us. "I introduce people to their own world," writes Lewin, "the world they live in and are familiar with but don't approach like a physicist - yet."

Borderline personality disorder, autism, narcissism, psychosis, Asperger's: All of these syndromes have one thing in common---lack of empathy. In some cases, this absence can be dangerous, but in others it can simply mean a different way of seeing the world. In The Science of Evil, Simon Baron-Cohen, an award-winning British researcher who has investigated psychology and autism for decades, develops a new brain-based theory of human cruelty.

The Trouble with Physics argues that a limited notion of time is holding physics back. It's time for a major revolution in scientific thought. The reality of time could be the key to the next big breakthrough in theoretical physics. What if the laws of physics themselves were not timeless? What if they could evolve? Time Reborn offers a radical new approach to cosmology that embraces the reality of time and opens up a whole new universe of possibilities.

How does the brain generate a conscious thought? And why does so much of our knowledge remain unconscious? Thanks to clever psychological and brain-imaging experiments, scientists are closer to cracking this mystery than ever before. In this lively book, Stanislas Dehaene describes the pioneering work his lab and the labs of other cognitive neuroscientists worldwide have accomplished in defining, testing, and explaining the brain events behind a conscious state.

The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity - by chewing, brewing, and snorting - some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the 5,000-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze Age medicine, a worm-killing birch fungus, knotted to his leggings.

Weaving decades of field observations with exciting new discoveries about the brain, Carl Safina's landmark book offers an intimate view of animal behavior to challenge the fixed boundary between humans and nonhuman animals.

Emma Gatewood told her family she was going on a walk and left her small Ohio hometown with a change of clothes and less than $200. The next anybody heard from her, this genteel, farm-reared, 67-year-old great-grandmother had walked 800 miles along the 2,050-mile Appalachian Trail. And in September 1955, atop Maine's Mount Katahdin, she sang the first verse of "America, the Beautiful" and proclaimed, "I said I'll do it, and I've done it."

The desire for dignity is universal and powerful. It is a motivating force behind all human interaction - in families, in communities, in the business world, and in relationships at the international level. When dignity is violated, the response is likely to involve aggression, even violence, hatred, and vengeance. On the other hand, when people treat one another with dignity, they become more connected and are able to create more meaningful relationships.

Bayes' rule appears to be a straightforward, one-line theorem: by updating our initial beliefs with objective new information, we get a new and improved belief. To its adherents, it is an elegant statement about learning from experience. To its opponents, it is subjectivity run amok. Sharon Bertsch McGrayne here explores this controversial theorem and the human obsessions surrounding it.

When Desert Solitaire was first published in 1968, it became the focus of a nationwide cult. Rude and sensitive. Thought-provoking and mystical. Angry and loving. Both Abbey and this book are all of these and more. Here, the legendary author of The Monkey Wrench Gang, Abbey's Road and many other critically acclaimed books vividly captures the essence of his life during three seasons as a park ranger in southeastern Utah.

Honeybees make decisions collectively-and democratically. Every year, faced with the life-or-death problem of choosing and traveling to a new home, honeybees stake everything on a process that includes collective fact-finding, vigorous debate, and consensus building. In fact, as world-renowned animal behaviorist Thomas Seeley reveals, these incredible insects have much to teach us when it comes to collective wisdom and effective decision making.

In a book destined to become a classic, biologist and acclaimed nature writer Bernd Heinrich takes listeners on an eye-opening journey through the hidden life of a forest. A lifetime observer of the natural world shares his vast knowledge and reflections on the trees of the Northeast woodlands and the rhythms of their seasons, from the DNA contained in an apple seed to the great branches beyond reach.

Einstein's theory of gravity, as beautiful as it is, seems to be in direct contradiction with another theory he helped create: quantum mechanics. From the explosions of neutron stars and the collisions of black holes to the modern scientific process as a means to seek truth and understanding in the cosmos, this audiobook takes the listener on a journey of learning and discovery that has been 100 years in the making.

Oxford Case Histories in Infection and Microbiology contains over 45 well structured cases, providing comprehensive coverage of the diagnostic and management dilemmas in clinical microbiology and infectious diseases. Each case comprises of a brief patient history with relevant clinical examination findings, thus insuring the listener is aware of how to confirm a diagnosis rapidly, with reference throughout to laboratory techniques, advice on therapy, epidemiological features, and areas which can be controversial.