In this special roundtable episode with editors from eClinicalMedicine, we welcome two new Senior Editors, Victoria Higgs and Jing Yuan, to the team, and Claudia Schaefer, Sundus Shafat Ahmad, and Charlotte Rowbottom chat with Hannah Linne to reflect on highlights of 2025 and share what they think will be prominent in 2026. The team discusses standout research papers, the launch of our LinkedIn and Bluesky social media pages, and highlights from the American Society of Haematology Annual 2025 meeting.

Looking ahead to 2026, the editors anticipate the growing role of AI in clinical practice and continued discussions on regulation, new Review commissions, two upcoming Series on gynaecological cancers and the new WHO guidance on follow-up care of small or sick newborns, and an exciting partnership with the International Agency for Research on Cancer for their International Scientific conference, marking their 60th anniversary year.

https://www.thelancet.com/series-do/childhood-cancer-asia

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00272-X/fulltext
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00408-0/fulltext
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00441-9/fulltext
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00442-0/fulltext

https://www.buzzsprout.com/1845316/episodes/17971614

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00518-8/fulltext

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00165-8/fulltext
https://www.buzzsprout.com/1845316/episodes/17273572

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00450-X/fulltext

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Mahdi Sheikh joins Elena Bellafante, Deputy Editor for eClinicalMedicine, to discuss the evidence that regular use of pharmaceutical opioids for pain management may be associated with a higher risk of developing certain cancers, particularly those already known to be linked to opium consumption.

Read the full article: https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00371-2/fulltext

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Giulia Zamagni joins Claudia Schaefer to discuss her recent Series of 4 papers from the Italian Global Burden of Disease collaborators providing the disease burden estimates and temporal trends for leukemia, multiple myeloma, non-Hodgkin lymphoma and Hodgkin lymphoma in Italy.

Click here to read the full text in this series: paper 1; paper 2; paper 3; paper 4

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Karin Modig and Yuge Zhang join Charlotte Rowbottom to discuss their recent work on the disease trajectories of centenarians in Sweden, covering disease burden, the rate of disease accumulation, and patterns of multimorbidity.

Read the full article:

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00328-1/fulltext?dgcid=buzzsprout_icw_podcast_September_25_eclinm

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Dr Marleen Vallinga and Dr Philippine Roijer join Hannah Linne to discuss their recent work on developing core outcome sets for feminising and masculinising genital gender-affirming surgery, the importance of gender-affirming surgery for transgender individuals, and the GenderCOS project.

Find out more about the GenderCOS project:

https://www.gendercos.org/

Read the associated articles:

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00255-X/fulltext?dgcid=buzzsprout_icw_podcast_August_25_eclinm

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00257-3/fulltext?dgcid=buzzsprout_icw_podcast_August_25_eclinm

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Sonja Aalbers talks with Owen Stretton about her group's systematic review and multilevel meta-analysis of trials assessing personally tailored music therapies for patients with anxiety and how they can offer effective, flexible, and scalable interventions for reducing anxiety symptoms.

Read the full article:

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00225-1/fulltext?dgcid=buzzsprout_icw_podcast_June_25_eclinm

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Dr. Jan Hontelez and Professor Till Barnighausen join Sundus Ahmad to discuss their modelling study which predicted changes in HIV deaths and new infections due to the PEPFAR funding freeze.

Read the full article:

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00165-8/fulltext?dgcid=buzzsprout_icw_podcast_Jun_25_eclinm

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Professor Jamie Lachman and Dr Qing Han join Rachel Kerslake to discuss their recent systematic review and meta analysis looking at the Prevalence of intimate partner violence among child marriage victims and the comparison with adult marriages.

Read the full article:

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00016-1/fulltext?dgcid=buzzsprout_icw_podcast_28-04-25_eclinm

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