In this episode, host Dr Julian Hoad BSc(Hons) BVetMed Hon MBVNA MRCVS, President of the BSAVA, interviews two leading voices in veterinary genetics to explore what genetic testing means for everyday practice.

Dr Leslie A. Lyons, PhD, Gilbreath McLorn Endowed Professor of Comparative Medicine at the University of Missouri, has identified over 40 inherited DNA variants in cats and published more than 200 peer-reviewed studies. A long-standing leader in feline genetics, she discusses the role of genetic testing in both pedigree and non-pedigree cats, the importance of wellness-related variants such as blood type and coagulation factors, and the potential of whole-genome sequencing to bring precision medicine into the consulting room.

Later, Dr Catherine Mellersh, Senior Research Associate at the University of Cambridge and Head of the Canine Genetics Centre, shares her pioneering work in canine inherited diseases. With a research career spanning three decades and multiple international awards, she explains how DNA testing is helping breeders make informed decisions, the realities of complex conditions such as hip dysplasia, and the responsibilities of both breeders and puppy buyers in reducing inherited disease.

This episode brings genetics into the real world of general practice, offering clear insights into when and how testing can guide clinicians, breeders, and owners alike.

Resources & Links:

• Canine Genetics Centre (CGC) – Led by Dr Catherine Mellersh, developing DNA tests to improve the health and welfare of future generations of dogs.
• Canine Genetic Testing (CAGT) – The commercial arm of the CGC, offering a wide range of tests, with all profits reinvested in research.
• University of Missouri – Feline Genetics and Comparative Medicine Lab – Dr Leslie Lyons’ lab, providing detailed information on breed-related genetic tests.
• OMIA – Online Mendelian Inheritance in Animals – Comprehensive catalogue of inherited disorders and genes in animals.
• PawPeds – Information resource for feline genetics, breeding, and health.
• DogWellNet – International Partnership for Dogs knowledge base.

Guest & Host Profiles:

• Dr Leslie A. Lyons – ORCID
• Dr Catherine Mellersh – Canine Genetics Centre
• Dr Julian Hoad – LinkedIn

This podcast was edited and produced by Contento Media Ltd.

In this opening episode of the WSAVA Podcast, host Dr Petra Černá speaks with two internationally recognised experts about how genetic testing is reshaping small animal practice.

Dr Jerold S. Bell, DVM, Adjunct Professor of Clinical Genetics at Tufts University and Chair of the WSAVA Hereditary Disease Committee, explains the different types of genetic tests, from direct DNA to marker-based approaches. He highlights examples of dominant and recessive traits in cats and dogs, and shares practical advice on how veterinarians can responsibly interpret results in practice.

Later in the episode, Dr Joshua A. Stern, DVM, PhD, DACVIM (Cardiology), Associate Dean for Research and Graduate Studies at NC State CVM, explores hypertrophic cardiomyopathy (HCM) in cats. He discusses the value and limitations of current genetic testing in breeds such as Maine Coons and Ragdolls, introduces promising therapies including rapamycin, and reflects on the rapid progress in feline genetics.

Together, these conversations provide practical insights for veterinarians seeking to use genetic tools more effectively in clinical decision-making.

Resources & Links:

• WSAVA Hereditary Disease Committee
• WSAVA Educational Resources
• DogWellNet
• PawPeds
• Genetic Testing: Practical Dos and Don’ts for Cats (JFMS)
• University of Missouri Feline Genetics
• Langford Vets Cat Genetic Testing
• Online Mendelian Inheritance in Animals
• UFAW: Welfare and Inherited Disorders in Cats

Guest & Host Profiles:

• Dr Jerold S. Bell, DVM – ResearchGate
• Dr Petra Černá – LinkedIn | Instagram
• Dr Joshua Stern – LinkedIn | Stern Lab | Twitter | Instagram

This podcast was edited and produced by Contento Media Ltd.

Veterinary medicine is more than a profession, it’s a global story. On the WSAVA Podcast, you’ll hear veterinarians from across the world share their experiences, insights, and solutions in animal health.

Our first series, created with the Hereditary Disease Committee, explores hereditary disease in dogs and cats - from understanding complex genetic conditions to creating healthier breeds for the future. Make sure to follow and subscribe in your favourite podcast player app to get notified when new episodes drop.

These are conversations for every veterinary professional - transforming care, one episode at a time.