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  • Can Carbon 60 Extend Lifespan? | Chris Burres | S10 - E6

    Can Carbon 60 Extend Lifespan? | Chris Burres | S10 - E6
    2026/11/09
    In this video: Can Carbon 60 Extend Lifespan? | Chris Burres ✅Valasta Astaxanthin : https://valasta.net/ (Checkout with code POI5 for 5% discount) ✅BBACK Shoes: https://bbackworld.us (Get 10% off your order with code POI10) ✅Nature's Marvels : https://profound-health.com/product-c... (A Trusted Source for Natural & Synthetic Bioregulators) ✅StemRegen: http://www.stemregen.co/drstephen (Special Offer: Save 15% Using Code "SBPOD" At Checkout) ✅Approved Medical Sollutions: https://approvedmedicalsolutions.com/ (Non-licensed patients can use code "sbarrett" for a 10% discount.) Please register your patients at - www.tremorstudy.com What if a molecule could help protect mitochondria, support cellular health, and potentially influence longevity? Could Carbon 60 (C60) be one of the most intriguing discoveries in longevity research? In this episode of The Pod of Inquiry, Dr. Stephen Barrett sits down with Chris Burres, Chief Scientist of MyVitalC and a pioneer in Carbon 60 manufacturing, to explore ESS60, the science behind the longevity molecule, and the famous rat study that reported a 90% increase in lifespan. From its Nobel Prize-winning discovery to its proposed role in mitochondrial function, this conversation explores the science, theories, and emerging research surrounding Carbon 60. IN THIS EPISODE: ⚛️ Carbon 60's discovery and Nobel Prize-winning structure 🐀 The famous 90% rat lifespan study 🔋 ESS60, mitochondria, and the BOSS theory 🛡️ Selective antioxidants and cellular protection 🧬 ESS60, glutathione, melatonin, and vitamin C 🥑 Olive oil vs. avocado oil vs. MCT oil 💤 Absorption, delivery, and sleep ⚙️ The catalytic converter theory 🌱 The foundations of longevity: sleep, nutrition, and exercise 🔬 Four upcoming MyVitalC research studies By the end, you'll understand why Chris calls it the "Mellow Molecule" and why Carbon 60 continues to attract attention in longevity and biohacking circles. EXCLUSIVE POD OF INQUIRY OFFER Visit the exclusive landing page for our audience: 🌐 https://myvitalc.com/podofinquiry Get up to 40% off, a $30 coupon, and a FREE PDF featuring 18 biohacking tips from leading longevity experts. Subscribe to The Pod of Inquiry for more conversations on human optimization, longevity, and the science of better health. If you enjoyed this episode, share it with a friend or colleague and leave a review to help more people discover the show. DISCLAIMER: This episode is for educational and informational purposes only and is not medical advice. Research findings and proposed mechanisms discussed are not established proof of benefits in humans. Always consult a qualified healthcare professional before making changes to your health routine. Follow Pod of Inquiry 📘 Facebook: https://www.facebook.com/podofinquiry 📸 Instagram: https://www.instagram.com/podofinquiry 🐦 X (Twitter): https://www.x.com/podofinquiry 🔗 LinkedIn (Dr. Stephen Barrett): https://www.linkedin.com/in/stephen-barrett-92776a51/ Visit our website https://podofinquiry.com/latest-episodes/ - click on the show link to read the show notes and get more information. Timestamps: 00:00 Chris Burres & the 90% Lifespan Study 01:17 Pod of Inquiry Intro 01:48 Meet Chris Burres & His Longevity Books 02:36 From Engineering to Entrepreneurship 05:37 What Is ESS60? 06:02 Carbon 60 & Its Discovery 08:22 The Nobel Prize Discovery 10:02 The Science of Carbon Fullerenes 11:16 Real-World Applications of C60 12:11 The 90% Rat Lifespan Study 14:54 Carbon 60 Absorption & Olive Oil 16:40 The BOSS Theory & Mitochondria 18:57 Sponsor: ValAsta 19:48 What Damages Mitochondria? 20:48 The Mardi Gras ROS Analogy 22:08 How ESS60 Works in the Body 23:08 ESS60 vs. Vitamin C & Astaxanthin 24:46 From Research to Human Supplement 28:12 Bringing ESS60 to Market 31:52 Inflammation & FDA Regulations 33:00 ESS60 & Mitochondrial Function 34:06 The Catalytic Converter Theory 35:35 Biomarkers & Health Optimization 37:50 Choosing the Right Oil for ESS60 38:57 Sublingual Absorption 39:14 ESS60 & Better Sleep 40:07 Chris's Personal ESS60 Routine 41:26 The Three Pillars of Longevity 42:08 Lessons from Longevity Experts 43:37 Mindset & Emotional Resilience 44:53 The Mellow Molecule 45:01 Pure ESS60 vs. Generic Carbon 60 46:35 New ESS60 Research Studies 50:09 ESS60 Skincare & Exclusive Offer 51:13 Discounts, Subscriptions & Books 53:19 Closing Remarks 53:36 Sponsor: Approved Medical Solutions 56:50 Disclaimer -- Hashtags -- #Carbon60 #ESS60 #Longevity #Mitochondria #AntiAgingResearch #Biohacking #ThePodOfInquiry
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    58 分
  • The Future of 3D Bunion Correction | Drs. Mojgan Tavakoli & Horst Knapp | S10 - E5

    The Future of 3D Bunion Correction | Drs. Mojgan Tavakoli & Horst Knapp | S10 - E5
    2026/11/02

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    (Non-licensed patients can use code "sbarrett" for a 10% discount.)
    Please register your patients at - www.tremorstudy.com

    Is bunion surgery really an easy fix? 🦶 Think again. Hallux valgus is a complex, three-dimensional deformity, and correcting it requires more than simply removing a bone bump.

    On this episode of The Pod of Inquiry, Dr. Stephen Barrett sits down with Dr. Mojgan Tavakoli and Dr. Horst Knapp, a husband-and-wife surgical team in Plano, Texas, to explore the evolution of bunion surgery and the future of 3D bunion correction with nerve-sparing Lapiplasty.

    With approximately 1,500 Lapiplasty procedures performed, they discuss how patient-specific instrumentation uses weight-bearing CT scans and custom 3D-printed surgical guides to plan precise corrections tailored to each patient's foot.

    🔎 IN THIS EPISODE:
    🦶 Why bunions are three-dimensional deformities
    🔬 How 3D imaging and patient-specific guides improve surgical planning
    📐 Why correcting metatarsal rotation matters
    ⚠️ Why waiting until a bunion hurts may be too late
    🦵 The role of equinus and rearfoot alignment in bunion correction
    🧠 Nerve-sparing techniques and preventing post-surgical nerve complications
    🩻 Why successful surgery is about patient outcomes, not just X-rays
    🔧 The limitations of surgical technology and the importance of clinical judgment

    Whether you're a foot and ankle surgeon, a healthcare professional, or someone exploring bunion treatment options, this conversation offers valuable insight into modern approaches to hallux valgus correction.

    🎙️ GUESTS
    Dr. Mojgan Tavakoli & Dr. Horst Knapp
    📍 Plano, Texas
    🌐 Website: dfwfoot.com


    Follow Pod of Inquiry
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    Visit our website https://podofinquiry.com/latest-episodes/ - click on the show link to read the show notes and get more information.


    Timestamps:
    00:00 Introduction to Nerve-Sparing Bunion Surgery
    01:44 How the Surgeons Met
    03:11 25 Years and 50,000 Patients
    06:30 Patient-Specific 3D Instrumentation
    08:40 Why Traditional Lapidus Surgery Varied
    10:22 The Evolution of Lapidus Surgery
    12:04 Why You Shouldn't Ignore Bunions
    14:41 Planning Bunion Surgery With Engineers
    16:55 Technology vs. Surgical Judgment
    18:44 Why Bunion Surgery Is Not Simple
    20:12 Sponsor: ValAsta
    21:03 The Importance of Strong Fixation
    22:46 Surgical Fixation and Surgeon Education
    24:45 Reading 3D Engineering Scans
    27:20 Why Traditional Bunion Surgeries Failed
    29:28 Showing Patients Their Planned Correction
    30:26 Equinus and Foot Alignment
    32:10 Preventing Repeat Forefoot Surgery
    34:06 Removing an Os Intermetatarseum
    34:43 Bone Shortening, Grafts and Metatarsalgia
    37:14 Plantar Plate Ruptures and Steroid Injections
    37:53 Nerve-Sparing Lapiplasty
    39:14 Sponsor: BBack 0524
    40:06 Reducing Post-Surgical Nerve Pain
    41:02 Deep Fibular Nerve and EHB Protection
    42:45 Surgical Results vs. Patient Outcomes
    45:10 Managing Surgical Complications
    46:27 Precision Bunion Correction With 3D Models
    48:21 Correcting Metatarsal Rotation
    49:39 Limitations of Patient-Specific Instrumentation
    51:25 Correcting Metatarsus Adductus
    52:55 Preventing Nerve Injuries and Neuromas
    53:59 Meet the Surgeons in Plano, Texas
    57:17 Sponsor: Nature's Marvels

    -- Hashtags --
    #BunionSurgery #Lapiplasty #3DBunionCorrection #FootSurgery #Podiatry #HalluxValgus #NerveSparing
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    59 分
  • Can Gum Health Affect Your Hormones? | Christine Horton | S10 - E4

    Can Gum Health Affect Your Hormones? | Christine Horton | S10 - E4
    2026/10/23

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    ✅Nature's Marvels : https://profound-health.com/product-c...
    (A Trusted Source for Natural & Synthetic Bioregulators)
    ✅StemRegen: http://www.stemregen.co/drstephen
    (Special Offer: Save 15% Using Code "SBPOD" At Checkout)
    ✅Approved Medical Sollutions: https://approvedmedicalsolutions.com/
    (Non-licensed patients can use code "sbarrett" for a 10% discount.)


    When was the last time your doctor asked about your gums? 🦷

    Polycystic ovary syndrome (PCOS) affects roughly 1 in 8 women, and an estimated 70% remain undiagnosed. But what if oral health plays a bigger role in hormonal and metabolic health than most people realize?

    On this episode of The Pod of Inquiry, Dr. Stephen Barrett welcomes Christine Horton, RDH, a registered dental hygienist and certified health coach who was diagnosed with PCOS at 17. Together, they explore the connection between the oral microbiome, gum disease, systemic inflammation, insulin resistance, and PCOS.

    Christine also discusses the proposed shift toward the term polyendocrine metabolic ovarian syndrome (PMOS), emphasizing the broader metabolic and endocrine factors involved in the condition.

    🔎 IN THIS EPISODE:
    • PCOS, insulin resistance, and metabolic health
    • The connection between gum disease and systemic inflammation
    • How treating periodontitis may improve blood sugar control
    • Oral bacteria, nitric oxide production, and antiseptic mouthwash
    • Periodontal probing depths, staging, and grading
    • Hidden sugars, vaping, nicotine pouches, and xylitol
    • Oil pulling and the root canal debate
    • Why oral health deserves a place in whole-body healthcare

    Whether you're interested in PCOS, diabetes, cardiovascular health, or the oral-systemic connection, this conversation explores why your mouth may reveal more about your overall health than you think.

    👍 Enjoyed this episode? Like, subscribe, and share it with someone interested in PCOS, hormonal health, or the oral microbiome. Leave a comment: When was the last time your doctor or dentist discussed your gum health?

    🌐 CONNECT WITH CHRISTINE HORTON
    Website: fusionhealthcoach.com
    Social Media: @PMOSPCOSHygienist
    Advocacy: PCOS Awareness Association

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    🔗 LinkedIn (Dr. Stephen Barrett): https://www.linkedin.com/in/stephen-barrett-92776a51/

    Visit our website https://podofinquiry.com/latest-episodes/ - click on the show link to read the show notes and get more information.


    Timestamps:
    00:00 Oral Health & PCOS
    01:22 PCOS Renamed to PMOS
    02:05 Christine Horton's Story
    05:29 PCOS Awareness
    07:19 Conventional PCOS Treatment
    09:13 What Happens in the Ovary?
    10:42 PCOS & Insulin Resistance
    13:16 Rotterdam Diagnostic Criteria
    13:38 Inflammation & Health Risks
    14:54 Oral Health Meets Medicine
    16:24 Sponsor: ValAsta
    17:49 Gum Disease & Systemic Inflammation
    19:23 Mouthwash & Nitric Oxide
    21:18 Oral Bacteria & Bloodstream
    22:49 The Nitrate Lunch Experiment
    24:03 Nitric Oxide & Neuropathy
    25:23 Know Your Gum Health
    27:17 Why Saving Teeth Matters
    28:38 Periodontal Staging & Grading
    31:47 Oral Health & PCOS
    32:18 Sponsor: BBack
    34:00 Gingivitis & Hidden Sugars
    36:19 Vaping, Nicotine & Oral Health
    38:58 Xylitol & Dental Health
    40:38 Oil Pulling: Does It Work?
    42:37 Root Canals vs. Extraction
    46:02 Phage Therapy & Medical Learning
    47:25 Find Christine Horton
    48:18 Sponsor: Approved Medical Solutions

    -- Hashtags --
    #PCOS #OralHealth #HormonalHealth #OralMicrobiome #InsulinResistance #GumDisease #PodOfInquiry
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    52 分
  • The Future of Brain Training | Dr. Michael Bagnell | S10 - E3

    The Future of Brain Training | Dr. Michael Bagnell | S10 - E3
    2026/10/19
    ✅Valasta Astaxanthin : https://valasta.net/ (Checkout with code POI5 for 5% discount) ✅BBACK Shoes: https://bbackworld.us (Get 10% off your order with code POI10) ✅Nature's Marvels : https://profound-health.com/product-c... (A Trusted Source for Natural & Synthetic Bioregulators) ✅StemRegen: http://www.stemregen.co/drstephen (Special Offer: Save 15% Using Code "SBPOD" At Checkout) ✅Approved Medical Sollutions: https://approvedmedicalsolutions.com/ (Non-licensed patients can use code "sbarrett" for a 10% discount.) Please register your patients at - www.tremorstudy.com What if the brain could be trained to function better through targeted neurological rehabilitation? 🧠 On this episode of The Pod of Inquiry, Dr. Stephen Barrett welcomes Dr. Michael Bagnell, a Miami-based functional neurologist with nearly four decades of experience, to explore brain function, neurological assessment, and innovative approaches to brain rehabilitation. Dr. Bagnell explains how functional neurology evaluates the brain's performance, identifies areas of weakness, and uses targeted stimulation and rehabilitation to support neurological function. In this episode, we explore: • How eye movements can reveal important clues about brain function • The comprehensive two-hour neurological exam, including eye tracking, qEEG, pupil responses, autonomic function, and the vestibular system • Photobiomodulation, PEMF, vagal stimulation, and 40 Hz median nerve stimulation in cognitive rehabilitation • Chronic pain, the periaqueductal gray, and the potential role of vertical eye movements • The Phoenix Sign story and a D5W case that challenged Dr. Barrett's thinking • Dolphin-assisted brain rehabilitation in the Florida Keys, echolocation recordings, and the challenges of researching dolphin interactions From functional neurology to emerging approaches in brain rehabilitation, this conversation examines how detailed assessment and targeted therapies may contribute to our understanding of neurological function. The discussion was so extensive that ADHD and anxiety had to wait for a follow-up episode with Dr. Bagnell. Follow Pod of Inquiry 📘 Facebook: https://www.facebook.com/podofinquiry 📸 Instagram: https://www.instagram.com/podofinquiry 🐦 X (Twitter): https://www.x.com/podofinquiry 🔗 LinkedIn (Dr. Stephen Barrett): https://www.linkedin.com/in/stephen-barrett-92776a51/ Visit our website https://podofinquiry.com/latest-episodes/ - click on the show link to read the show notes and get more information. Timestamps: 00:00 The Ultimate Brain Gym 00:40 Pod of Inquiry Intro 01:11 Meet Dr. Michael Bagnell 01:34 From Medical School to Functional Neurology 05:23 Mind-Body Connection & Bioelectronic Medicine 06:31 The Neuroplasticity Myth 06:47 Vagal Stimulation & Dysautonomia 07:45 Why Deep Brain Evaluation Matters 08:09 Eye Tracking: A Window Into the Brain 09:00 Inside the Comprehensive Brain Exam 11:03 SPECT Imaging & Chronic Pain 11:49 Brain Mapping & Cognitive Health 13:40 Alzheimer's, Dementia & Personal Stories 14:48 The Brain as a Muscle 16:21 Why Brain Exams Take Two Hours 16:35 Sponsor: ValAsta 17:26 The Patient Who Changed His Approach 17:58 The Brain Rehabilitation Toolkit 21:45 Brain Energy & TMS 23:06 The Phoenix Sign Discovery 26:15 From Peripheral Nerves to the Brain 26:34 Nitric Oxide, Blood Flow & Nattokinase 26:59 Autonomic Control of Blood Flow 27:31 The Phoenix Sign & Nerve Recovery 28:17 Chronic Pain, Eye Movements & the PAG 30:32 The Subjective Experience of Pain 31:11 Eye Tracking Diagnostics & VNG 32:19 The PAG and Chronic Pain 32:48 Sponsor: BBACK 33:48 Which Came First: Pain or Eye Dysfunction? 34:20 When Diagnosis Becomes Therapy 34:34 Training Weak Eye Movements 35:24 Progressive Loading for Brain Rehab 36:21 Testing Responses During Brain Exams 38:09 Brain Rehab Programs & Recovery 38:46 Why Alzheimer's Is So Complex 39:45 The Brain as a Network 40:19 Dolphin-Assisted Brain Rehabilitation 40:34 Designing Dolphin Therapy Programs 43:40 Dolphin Meditation & Echolocation 44:03 Restarting the Dolphin Program 44:36 The Dolphin Therapy Placebo Effect? 45:04 Measuring Brain Changes With AI 46:28 Why Dolphin Research Faces Ethical Hurdles 46:41 Part Two: ADHD & Anxiety 47:20 The Upcoming Nerve Meeting 47:31 Find Dr. Michael Bagnell 48:33 Sponsor: Nature's Marvels 49:48 Disclaimer -- Hashtags -- #FunctionalNeurology #BrainHealth #Neuroplasticity #EyeTracking #BrainOptimization #DrMichaelBagnel
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    51 分
  • The Power of Phage Therapy | Dr. Robert Schooley | S10 - E2

    The Power of Phage Therapy | Dr. Robert Schooley | S10 - E2
    2026/10/12
    ✅Valasta Astaxanthin : https://valasta.net/ (Checkout with code POI5 for 5% discount) ✅BBACK Shoes: https://bbackworld.us (Get 10% off your order with code POI10) ✅Nature's Marvels : https://profound-health.com/product-c... (A Trusted Source for Natural & Synthetic Bioregulators) ✅StemRegen: http://www.stemregen.co/drstephen (Special Offer: Save 15% Using Code "SBPOD" At Checkout) ✅Approved Medical Sollutions: https://approvedmedicalsolutions.com/ (Non-licensed patients can use code "sbarrett" for a 10% discount.) Please register your patients at - www.tremorstudy.com What if viruses could save your life when antibiotics fail? Discover the science of bacteriophage therapy and the remarkable story behind one of the most extraordinary cases in modern medicine. On this episode of The Pod of Inquiry, Dr. Robert "Chip" Schooley, Distinguished Professor of Medicine at UC San Diego and co-director of IPATH, joins Dr. Stephen Barrett to explain how bacteriophages helped treat a life-threatening, multidrug-resistant Acinetobacter infection in UC San Diego professor Tom Patterson. After months in intensive care and repeated antibiotic failures, Patterson's medical team turned to an experimental approach: intravenous phage therapy, using viruses that infect and kill bacteria. Dr. Schooley takes us behind the scenes of this groundbreaking case, including the international effort to locate matching phages and the scientific detective work that helped guide treatment. IN THIS EPISODE: 🔬 What bacteriophages are and how they target bacteria 🦠 The science behind phage therapy and antibiotic-resistant superbugs 🧬 How bacteria defend themselves using restriction enzymes and CRISPR 🩺 Why bacterial biofilms make prosthetic joint infections difficult to treat 🌎 The challenges of sourcing phages for life-threatening infections 📊 What researchers know about phage therapy outcomes and its limitations 💡 One important step clinicians can take: asking their laboratory to preserve bacterial isolates for potential phage testing With antimicrobial resistance threatening the effectiveness of existing antibiotics, could bacteriophage therapy become an important part of the future of infectious disease treatment? Watch this fascinating conversation with Dr. Robert Schooley to explore the science, challenges, and potential of personalized phage therapy. 👍 LIKE this video, SUBSCRIBE to The Pod of Inquiry, and turn on notifications for more conversations exploring human optimization and understanding. Follow Pod of Inquiry 📘 Facebook: https://www.facebook.com/podofinquiry 📸 Instagram: https://www.instagram.com/podofinquiry 🐦 X (Twitter): https://www.x.com/podofinquiry 🔗 LinkedIn (Dr. Stephen Barrett): https://www.linkedin.com/in/stephen-barrett-92776a51/ Visit our website https://podofinquiry.com/latest-episodes/ - click on the show link to read the show notes and get more information. Timestamps: 00:00 Episode Preview 01:03 Pod of Inquiry Intro 01:31 Dr. Schooley's Background 02:23 Illness in Egypt 03:36 Drug-Resistant Acinetobacter 04:20 Why Acinetobacter Is Dangerous 05:12 ICU Decline 06:07 Organ Failure 06:33 Discovering Phage Therapy 07:38 Taking the Risk 08:32 FDA Emergency Approval 11:41 Convincing the ICU Team 13:10 Matching Phages 13:58 Global Phage Search 15:20 Finding New Phages 15:46 U.S. Navy Phage Program 16:55 Phage Production 18:22 Phage Purification 19:15 IV Phage Therapy 20:33 Tom's Recovery Begins 20:48 ValAsta Sponsor 21:39 Clinical Improvement 22:05 Endotoxin Concerns 22:52 The 5 A.M. Emergency Call 24:07 Investigating Endotoxins 26:16 Secondary Infection 26:47 Atrial Fibrillation 27:53 Tom's Long-Term Recovery 28:20 Acinetobacter Transmission 29:28 What Are Phages? 31:01 Phages on Earth 31:43 Phages in the Gut 32:28 Bacterial Defenses 33:22 CRISPR and Restriction Enzymes 34:32 Phage Adaptation 35:38 Phage Resistance 36:50 Phage–Antibiotic Synergy 37:26 Phage Pharmacology 38:47 The Future of Phage Therapy 40:12 UCSD's IPATH Center 40:40 BBack Footwear Sponsor 41:33 IPATH Physician Support 42:08 Treatment Barriers 42:52 Finding Difficult Phages 43:59 Genetic Engineering 45:11 Treatment Costs 46:56 Patient Eligibility 48:06 Saving Bacterial Isolates 48:39 Key Tip for Physicians 49:11 Phage Therapy Success Rates 51:40 Last-Resort Treatment 52:16 Prosthetic Joint Infections 53:28 Breaking Down Biofilms 54:12 Implant and Biofilm Risks 56:15 Contacting IPATH 57:41 Phages vs. Antibiotics 58:41 Funding Future Research 59:28 Approved Medical Solutions Sponsor -- Hashtags -- #PhageTherapy #Bacteriophages #AntibioticResistance #Superbugs #DrRobertSchooley #ThePodOfInquiry
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    1 時間 4 分
  • Can We Trust Modern Medicine? | Dr. Aseem Malhotra | S10 - E1

    Can We Trust Modern Medicine? | Dr. Aseem Malhotra | S10 - E1
    2026/10/05
    ✅Valasta Astaxanthin : https://valasta.net/ (Checkout with code POI5 for 5% discount) ✅BBACK Shoes: https://bbackworld.us (Get 10% off your order with code POI10) ✅Nature's Marvels : https://profound-health.com/product-c... (A Trusted Source for Natural & Synthetic Bioregulators) ✅StemRegen: http://www.stemregen.co/drstephen (Special Offer: Save 15% Using Code "SBPOD" At Checkout) ✅Approved Medical Sollutions: https://approvedmedicalsolutions.com/ (Non-licensed patients can use code "sbarrett" for a 10% discount.) Please register your patients at - www.tremorstudy.com Season 10 of The Pod of Inquiry is officially live, and we're opening with cardiologist Dr. Aseem Malhotra for a wide-ranging conversation about statins, medical research, pharmaceutical influence, and restoring trust in medicine. Dr. Malhotra is a consultant cardiologist with more than 25 years in medicine, author of A Statin-Free Life, creator of First Do No Pharm, and Chief Medical Advisor to the MAHA movement. His views on cardiovascular health and evidence-based medicine have made him a prominent voice in the debate over statins and modern healthcare. In this episode, Dr. Malhotra discusses: ➡️ What statin trials show in absolute risk terms ➡️ How pharma and medical journals interact ➡️ Ghostwriting, Vioxx, and clinical-trial data ➡️ His views on RFK Jr., Jay Bhattacharya, and Andy Burnham ➡️ The legislation he believes could improve medical transparency ➡️ Whether drug companies should test their own drugs ➡️ How physicians can help restore trust in medicine The conversation also ends on a hopeful note, with Dr. Malhotra challenging physicians to question established practices and advocate for better healthcare for future generations. ▶️ Subscribe to The Pod of Inquiry for more conversations on human optimization, health, medicine, and science. If you found this conversation valuable, share it with a colleague and leave a review. It genuinely helps The Pod of Inquiry grow. Follow Pod of Inquiry 📘 Facebook: https://www.facebook.com/podofinquiry 📸 Instagram: https://www.instagram.com/podofinquiry 🐦 X (Twitter): https://www.x.com/podofinquiry 🔗 LinkedIn (Dr. Stephen Barrett): https://www.linkedin.com/in/stephen-barrett-92776a51/ Visit our website https://podofinquiry.com/latest-episodes/ - click on the show link to read the show notes and get more information. Timestamps: 00:00 Season 10 Opener — Meet Dr. Aseem Malhotra 01:35 Pod of Inquiry Intro 02:05 Dr. Malhotra's Medical Background 03:21 The Heart Attack Patient Who Changed His Thinking 04:30 Hospital Food & Low-Fat Guidelines 05:03 A Statin-Free Life 06:01 Statins & the "Lower Is Better" Hypothesis 07:28 The Absolute Benefit of Statins 08:00 Statin Side Effects 08:34 Drugs vs. Lifestyle Intervention 09:15 Why Cardiology Hasn't Changed Course 10:59 How Science Changes 11:45 The Origins of Cholesterol Fear 12:41 The Flexner Report & Medicine as a Religion 13:28 MAHA, RFK Jr. & Aseem's Journey 15:32 MAHA Policy & Dr. Jay Bhattacharya 17:00 Friendship with Andy Burnham 18:01 Food & Vaccines 18:15 Sponsor: ValAsta Astaxanthin 19:15 Vaccines & the Henry Ford Analysis 19:37 Risk-Benefit Assessment & Vaccination 21:01 Informed Consent & COVID-19 Vaccines 21:17 Free Markets & Corporate Power in Healthcare 23:38 Humility & Medical Truth 25:14 NHS Ethics & Patient Care 26:20 Truth, Politics & Medicine 26:43 Trusting Medical Journals 28:13 Why Most Research Findings Are False 29:04 Reanalyzing Pfizer & Moderna Trials 29:50 How Medical Journals Profit From Pharma 30:45 Can We Trust Medical Literature? 31:52 Changing the Medical System 32:47 First Do No Pharm & Vioxx Ghostwriting 33:34 Why Ghostwriting Is Legal 35:10 Sponsor: BBack Footwear 36:18 Pharma Liability & Corporate Power 37:52 The Myth of Independent Medical Regulation 39:09 Who Should Test New Drugs? 39:22 How Clinical Trials Can Be Gamed 40:30 Speaking Up for Future Generations 40:59 FDA Testimony & Regulatory Conflicts 42:02 Rebuilding Public Trust in Medicine 43:03 The Legislation That Could Change Medicine 44:07 UK vs. US: Where Can Medicine Change? 45:26 GLP-1 Drugs & Childhood Obesity 46:50 The "More Drugs for More People" Model 47:38 mRNA Vaccines & Cancer Trials 49:22 Excess Deaths & Alternative Media 50:18 Hierarchy & Obedience in Medicine 51:57 Hope, Civil Rights & Medical Change 52:35 Sponsor: Approved Medical Solutions 54:40 Closing Remarks 55:48 Disclaimer -- Hashtags -- #AseemMalhotra #Statins #Cardiology #MedicalResearch #Healthcare #ThePodOfInquiry #PharmaceuticalIndustry
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    57 分
  • Can Spermidine Slow Aging? | Leslie Kenny | S9 - E20

    Can Spermidine Slow Aging? | Leslie Kenny | S9 - E20
    2026/09/28

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    ✅BBACK Shoes: https://bbackworld.us
    (Get 10% off your order with code POI10)
    ✅Nature's Marvels : https://profound-health.com/product-c...
    (A Trusted Source for Natural & Synthetic Bioregulators)
    ✅StemRegen: http://www.stemregen.co/drstephen
    (Special Offer: Save 15% Using Code "SBPOD" At Checkout)
    ✅Approved Medical Sollutions: https://approvedmedicalsolutions.com/
    (Non-licensed patients can use code "sbarrett" for a 10% discount.)
    Please register your patients at - www.tremorstudy.com

    What if your cells had their own cleanup crew?

    This week, Dr. Stephen Barrett sits down with Leslie Kenny—CEO of Oxford Healthspan and co-founder of the Oxford Longevity Project—to explore the science of spermidine, autophagy, and healthy aging.

    At just 39, Leslie was diagnosed with both rheumatoid arthritis and lupus during her fifth round of IVF. Refusing to accept a bleak prognosis, she embarked on a journey through immunology, longevity research, and lifestyle medicine that ultimately led her to one of the most fascinating compounds in aging science: spermidine.

    In this episode:

    ➡️What autophagy is and why it declines with age
    ➡️The Nobel Prize–winning science behind cellular recycling
    ➡️Senescent "zombie" cells, SASP, and chronic inflammation
    ➡️Why spermidine is considered a senomorphic rather than a senolytic
    ➡️Natural food sources of spermidine and the story behind Primadine
    ➡️The vagus nerve, ACE scores, thyroid health, and intergenerational stress

    If you're interested in longevity, cellular health, inflammation, or evidence-based healthy aging, this episode is packed with practical insights and cutting-edge research.


    Follow Pod of Inquiry
    📘 Facebook: https://www.facebook.com/podofinquiry
    📸 Instagram: https://www.instagram.com/podofinquiry
    🐦 X (Twitter): https://www.x.com/podofinquiry
    🔗 LinkedIn (Dr. Stephen Barrett): https://www.linkedin.com/in/stephen-barrett-92776a51/

    Visit our website https://podofinquiry.com/latest-episodes/ - click on the show link to read the show notes and get more information.


    Timestamps:
    00:00 Cold Open — Meet Leslie Kenny
    01:32 Leslie's Origin Story
    02:12 Diagnosed with RA & Lupus at 39
    07:12 Throw the Kitchen Sink at It
    08:50 IVIG & Immune Balance
    11:25 When Evidence Isn't "Significant"
    12:19 Inflammaging & Lifestyle Reset
    15:00 Labs Return to Normal
    16:20 Why Doctors Miss the "Why"
    17:55 Motherhood & Oxford Connections
    19:45 ValAsta Sponsor
    20:36 Discovering Spermidine
    22:32 Vagus Nerve & RA
    25:48 Trauma, Vagal Tone & Inflammation
    26:35 The ACE Test Explained
    29:01 Paths to Remission
    30:43 Treating Root Causes
    33:10 Famine, Trauma & Thyroid
    35:06 Hashimoto's & Fertility
    37:29 What Is Autophagy?
    38:39 BBACK Sponsor
    39:31 The Nobel Prize for Autophagy
    40:46 Zombie Cells, SASP & Senomorphics
    45:23 The Molecules We Lose With Age
    45:55 Where Spermidine Comes From
    46:21 The Story Behind Primadine
    47:55 Best Dietary Sources
    49:30 Why Japan? Clean Sourcing Explained
    51:55 Easy Ways to Take Spermidine
    52:42 A Gluten-Free Spermidine Option
    53:30 Oxford Longevity Project & POI15
    55:37 Final Thoughts
    56:31 Outro

    -- Hashtags --
    #longevity #autophagy #spermidine #healthyaging #cellularhealth #podcast #science #wellness
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    1 時間
  • How He Survived the Epic Deca? | JD Tremblay | S9 - E19

    How He Survived the Epic Deca? | JD Tremblay | S9 - E19
    2026/09/21

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    What happens when you push the human body and mind through 10 Ironman triathlons in 10 consecutive days?

    JD Trembley knows firsthand.

    A French-Canadian military veteran, integrated engineer, and naturopath, JD is one of only three people known to have completed the Epic Deca — 10 Ironman triathlons across six Hawaiian Islands in 10 days, while surviving on extremely limited sleep.

    The physical and mental cost was enormous. JD describes burning more than 10,000 calories a day, struggling to maintain weight, and eventually developing severe loss of sensation that lasted for more than six months after the race.

    In this episode of The Pod of Inquiry, we explore extreme endurance, sleep deprivation, mental toughness, nutrition, neurological consequences, and what JD learned from pushing himself beyond conventional limits.

    We also discuss how his Epic Deca experience eventually led to the Hungry Warrior Academy, his coaching framework for helping men rebuild discipline, purpose, and resilience.

    🔥 IN THIS EPISODE:
    • 10 Ironmans in 10 consecutive days across six Hawaiian Islands
    • Burning 10,000+ calories a day during extreme endurance
    • Why JD says endurance is "80% psychological"
    • Sleep deprivation and cognitive load
    • His experience with induced peripheral neuropathy
    • A vegan endurance nutrition strategy
    • Preparing mentally for fear before the race
    • From Epic Deca to the Hungry Warrior Academy
    • Discipline, resilience, purpose, and human performance

    "It is 80% psychological, and then the rest is all physical."
    — JD Trembley


    Follow Pod of Inquiry
    📘 Facebook: https://www.facebook.com/podofinquiry
    📸 Instagram: https://www.instagram.com/podofinquiry
    🐦 X (Twitter): https://www.x.com/podofinquiry
    🔗 LinkedIn (Dr. Stephen Barrett): https://www.linkedin.com/in/stephen-barrett-92776a51/

    Visit our website https://podofinquiry.com/latest-episodes/ - click on the show link to read the show notes and get more information.


    Timestamps:
    00:00 Introduction
    02:49 Background & Professional Journey
    04:44 How the Epic Deca Came About
    08:54 Course Format & Caloric Demands
    10:35 Sleep Deprivation Strategy
    12:25 The 80% Psychological Framework
    15:43 Three Stages of Breakdown
    16:44 ValAsta Sponsor
    17:34 Induced Peripheral Neuropathy
    21:22 Nutrition Strategy
    23:46 Hardest: Swim, Bike, or Run
    25:06 Mental Games & Shark Preparation
    28:50 From Epic Deca to a Book & Academy
    29:49 Hungry Warrior Academy
    31:14 BBack Sponsor
    32:13 Who the Academy Serves
    33:00 Demographics & Philosophy
    36:10 Outcomes & Timeline
    38:23 No Psychedelic-Like States
    40:26 Cold Water Immersion & IISA
    43:30 The Turning Point Behind the Academy
    45:15 Where to Find the Academy

    -- Hashtags --
    #EpicDeca #Ironman #MentalToughness #Endurance #SleepDeprivation #HumanPerformance #PodOfInquiry
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    49 分