SS-31 (Elamipretide) in 2025: The FDA-Approved Mitochondrial Reset for Long COVID and ME/CFS

Description: Welcome back to The Human 5.0 Project! In this episode, we dive into SS-31 (Elamipretide) — the peptide that became the first FDA-approved mitochondrial repair therapy for a rare disease in 2025, and how it’s transforming our understanding of fatigue medicine.

In this episode, we cover:

• Why SS-31 exploded in 2025 and the human data behind it

• How SS-31 works inside mitochondria to restore energy production and reduce post-viral crashes

• The exact labs that show it’s working and the research-grade protocols used in trials

• What the FDA approval for Barth syndrome means and why SS-31 is still off-label for Long COVID and ME/CFS

If you’re struggling with relentless fatigue or know someone who is, this episode is for you.

📥 Download the free SS-31 Protocol Guide (labs, stacks, dosing frameworks):

🔔 Subscribe for more cutting-edge biohacking insights.

For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.

And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.

#SS31 #Elamipretide #MitochondrialHealth #LongCOVID #ME/CFS #FatigueRecovery #FDAApproved #Mitochondria #Biohacking #FunctionalMedicine #ChronicFatigue #HealthTech #Human5.0Project #MitochondrialRepair #EnergyReset#Human50Project

TB-500 + TB4: Rapid Joint Repair, Hair Growth Signals, and Brain Fog Improvements? What 2025 Data Shows

TB-500 and Thymosin Beta-4 (TB4) are peptides originally studied for tissue repair and immune signaling — and in 2025, they’re gaining attention for their potential roles in joint recovery, hair density support, and cognitive clarity.

In this episode of The Human 5.0 Project, we break down: • What TB-500 and TB4 actually do at the cellular level • 2025 human and pilot data on tendon healing, inflammation reduction, and neurovascular support • Why athletes, clinicians, and biohackers are using these peptides as part of a repair-first strategy • Early findings in brain fog and post-viral cognitive symptoms • Safety, legality, and lab markers to monitor

These peptides aren’t magic — but they may act as part of the body’s natural repair crew when used responsibly and under supervision.

🔗 Full episode link in bio 📄 Free TB-500 + TB4 cheat sheet

For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.

And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.

⚠️ Educational content only. Not medical advice.

#TB500 #TB4 #ThymosinBeta4 #PeptideTherapy #InjuryRecovery #BrainFog #HairGrowth #Longevity #Biohacking #JointHealth #Neuroprotection #FunctionalMedicine #LongCOVID #PeptideHealing #Human50Project

If you’ve had COVID and now feel like your brain is wrapped in cotton — words vanish mid-sentence, simple tasks feel overwhelming, and mental fatigue hits after just minutes — you’re not alone.

This is Long COVID brain fog, still affecting an estimated 10–20% of everyone infected since 2020 — over 100 million people worldwide.

In this deep-dive episode of The Human 5.0 Project, we break down what’s actually happening in the brain, why many standard evaluations miss it, and the 2025 clinical and functional medicine protocols that are helping people recover cognitive clarity.

• The 2025 clinical picture of Long COVID brain fog, including the cognitive triad neurologists recognize • Why it happens: persistent spike protein fragments, micro-clots, mast-cell activation, and mitochondrial shutdown • The labs most doctors skip (hs-CRP, D-dimer, omega-3 index, NAD proxies) • Proven 2025 modalities being used right now: nicotine patches, peptides (BPC-157, SS-31, VIP nasal), HBOT, red-light therapy, guanfacine, and more • Diet and supplement stacks that actually move the needle (nattokinase, NAC, cyclical keto, PEA) • A realistic 90-day “get my brain back” decision tree

If you’re dealing with focus loss, word-finding difficulty, mental crashes after exertion, or know someone who is — this episode gives you the tools clinics and researchers are using now.

📥 Download the free Long COVID Brain Fog Reversal Checklist (longevity website): 👉 BiohackerDepot.com

🧬 Research-grade tools: 👉 PeptideSphere.com

💬 Comment below: What’s your #1 brain fog symptom? 🔔 Subscribe for root-cause biohacking — next up: Hashimoto’s reversal protocols.

#LongCOVID #BrainFog #LongCOVIDBrainFog #PostCOVID #LongCOVIDRecovery #CognitiveHealth #PostViralFatigue #FunctionalMedicine #Biohacking #PeptideTherapy #HBOT #NicotinePatch #Nattokinase #RedLightTherapy #Human50Project

"Unveiling the Hidden Causes and Advanced Approaches for Better Thyroid Health"

n this episode of The Human 5.0 Project, we dive deep into Hashimoto’s thyroiditis, exploring the hidden causes that mainstream medicine often overlooks. Discover why T4-only therapy may not be enough, the importance of comprehensive lab testing, and cutting-edge strategies that are changing the way we approach thyroid health in 2025.

Key Points:

• The hidden timeline of Hashimoto’s and why early immune markers matter.

• Why standard treatments often fail and the role of T3 and desiccated thyroid.

• Innovative peptide therapies and lifestyle interventions that are paving the way for better outcomes.

Let’s raise the standard of care: Labs first. Meds when necessary. Personalized healing always.

Hit subscribe—next week we decode long-COVID brain fog.

Download the free Hashimoto’s Reversal Checklist

For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.

And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.

#Hashimotos #HashimotosThyroiditis #ThyroidHealth #AutoimmuneThyroid #HashimotosAwareness #ThyroidLabs #TPOAntibodies #ReverseT3 #FunctionalMedicineThyroid #RootCauseThyroid #GlutenFreeHashimotos #LDNThyroid #ThymosinAlpha1 #BPC157Thyroid #SeleniumForThyroid #MyoInositolHashimotos #T3Therapy #DesiccatedThyroid #HypothyroidismTreatment #AutoimmuneReversal #BiohackingThyroid #WomensThyroidHealth #LongevityThyroid #MetabolicHealth #FunctionalMedicine #PeptideTherapy #Human50Project #UltimateBiohacker10X

Is depression really a “serotonin problem”… or something your doctor didn’t check? In today’s episode, we’re breaking down the five real biological and lifestyle pathways that can mimic depression—and why SO many people get put on meds before anyone even runs basic labs.

As a retired MD who has seen countless rushed admissions and missed diagnoses, I’m pulling back the curtain on what depression often really is: • Metabolic dysfunction • Nutrient deficiencies • Inflammatory brain stress • Loneliness-driven cortisol overload • Medication side effects

This deep dive gives you the exact roadmap to identify root causes before going down the trial-and-error medication path.

• The $29–$89 labs to run right now (TSH, ferritin, B12, hs-CRP, omega-3 index) • Why magnesium glycinate can calm glutamate-driven anxiety better than you think • How the UCLA Loneliness Scale identifies social isolation depression • Why post-COVID depression often needs metabolic repair (T3 + berberine) instead of SSRIs • The hidden drug interactions that can worsen mood (like statins depleting CoQ10)

If you’ve ever wondered why standard antidepressants don’t always work—or why someone you love still struggles despite being “treated”—this episode is a must-watch.

Let’s raise the standard of care: Labs first. Meds when necessary. Personalized healing always.

Hit subscribe—next week we decode long-COVID brain fog.

For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.

And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.

#Depression #MentalHealth #RootCauseMedicine #MetabolicHealth #LabTesting #FunctionalMedicine #PostCovid #Inflammation #HormoneHealth #Ferritin #B12Deficiency #ThyroidHealth #Cortisol #BrainHealth #AnxietyRelief #Longevity #HealthOptimization #Biohacking #NutrientDeficiency #HolisticHealth #DepressionLabs #SSRIFail #ThyroidDepression #B12Crash #InsulinResistanceMood #PhysicianPodcast #MentalHealthHack #BiohackingDepression #Omega3Index #CortisolRhythm #MagnesiumForMood #LonelinessEpidemic #PostCovidFog #CoQ10Deficiency #PsychWardExitPlan #UltimateBiohacker10X #Human50Project #RootCauseFix #AshwagandhaWins

Microplastics are now in our food, water, air—even our bloodstream. In this episode, we break down exactly where microplastics come from, how they enter the human body, the health risks they pose, and the emerging science on removing them.

We also cover: • The top home and lifestyle sources of microplastics • How to detox microplastics naturally • What works, what doesn’t, and what’s emerging • House and lifestyle upgrades to reduce plastic load • How microplastics affect hormones, inflammation, mitochondria, fertility, and aging • Biohacker strategies to protect your cells and extend your healthspan

If you care about longevity, detoxification, and metabolic performance, this is a must-watch.

Comment below: What shocked you most about microplastics?

For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.

And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.

#Microplastics #Detox #Healthspan #Longevity #Biohacking #Toxins #EnvironmentalHealth #NAD #Glutathione #HormoneDisruption #EndocrineDisruptors #UltimateBiohacker10X #HumanFiveProject #PFAS #Nanoplastics #CleanLiving

The Cellular Energy Masterclass: NAD+ Precursors for Peak Performance & Healthspan

In this deep-dive episode, we break down the full science behind NAD+, the molecule your mitochondria depend on for energy, repair, and metabolic resilience. We compare major NAD+ precursors—NMN, NR, Niacin, Niacinamide, NADH—and explain how each works, how they differ, and how to use them strategically for peak performance and extended healthspan.

🔥 What you’ll learn: • What NAD+ actually does inside your cells • Why NAD+ declines with age — and how to reverse it • NMN vs NR vs Niacin vs NADH: Mechanisms & differences • Dosing strategies for energy, recovery, and longevity • Synergistic stacks for mitochondrial upgrade • How NAD+ precursors fit into a full biohacking system • The latest research on healthspan extension

For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.

And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.

#NAD #NADPlus #NMN #NR #Niacin #NADH #Biohacking #Longevity #AntiAging #Mitochondria #EnergyProduction #Healthspan #CellularEnergy #UltimateBiohacker10X #Human5.0Project #Human5Project

GLP-1 Showdown: Semaglutide vs Tirzepatide vs Retatrutide (+ Cagrilintide, Mazdutide, Survodutide) | Ultimate Biohacker 10X

In today’s episode of The Human 5.0 Project, we break down the ultimate incretin showdown — the real science behind the world’s most powerful metabolic and longevity drugs. Whether you're exploring Semaglutide, Tirzepatide, Retatrutide, CagriSema (Cagrilintide + Semaglutide), Mazdutide, or Survodutide, this episode gives you everything you need to understand which one fits your goals.

🔥 What You'll Learn: • How GLP-1, GIP, glucagon, and amylin pathways really work • Which compounds deliver the highest weight-loss percentages • Longevity benefits: inflammation reduction, heart protection, metabolic reset • Side effects, management strategies, titration tips • How biohackers integrate these with peptides, supplements & lifestyle stacks • Which drug is best for fat loss vs metabolic healthspan • What’s coming in 2025–2027: the future of incretin therapy

If you’ve wondered why people are losing 15–24% of their body weight… or how these compounds might extend your healthspan, this is the episode for you.

👉 Longevity protocols & stacks: https://biohackerdepot.com 👉 Research-grade peptides & agonists: https://peptidesphere.com

#GLP1 #Semaglutide #Ozempic #Wegovy #Tirzepatide #Mounjaro #Zepbound #Retatrutide #Cagrilintide #CagriSema #Mazdutide #Survodutide #WeightLoss2025 #MetabolicHealth #Longevity #Biohacking #FatLoss #HealthSpan #IncretinTherapy #AntiAging #PeptideTherapy #UltimateBiohacker10X #Human50Project #MetabolicReset