Welcome back to Infinite Health, where today’s episode dives into sweeping changes in cardiovascular medicine and what they mean for you. The conversation focused on breakthrough developments in cholesterol-lowering therapies, emerging tests for heart disease risk, and practical strategies for managing elevated lipoprotein(a), or Lp. One concept discussed was the advent of the first oral PCSK9 inhibitor and updates on drugs targeting previously “untreatable” risk factors. A key theme that emerged was the importance of looking beyond just the numbers why lowering a biomarker doesn’t always translate to saved lives, and how new guidelines are pushing for more personalized care. The discussion explored genetic risk, evidence-based drug choices, and a step-by-step approach to navigating confusing lab results. Whether you’re a longtime patient, clinician, or just curious about staying heart-healthy, this episode delivers clarity, myth-busting, and action steps rooted in the latest science.

00:00 Introducing Dr. Moran's background

05:10 Explaining ApoB and new guidelines

07:48 Blocking PCSK9 to reduce LDL

11:01 Macrocyclic peptide cholesterol treatment

16:38 2026 guidelines recommend lipoprotein testing

17:40 Discussing Lp(a) treatment trials

21:17 Negative trial results for new drugs

25:27 Understanding heart disease risk factors

29:45 Understanding aortic valve stenosis

30:52 Understanding high Lp levels

36:49 Sharing the episode with others

37:35 Educational purpose and medical disclaimers

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Welcome back to Infinite Health! In today's episode, Dr. Arasi Maran unravels the fascinating story behind one of modern medicine’s small but mighty marvels: the stent. From its humble, kitchen-counter origins in 1970s Zurich to its life-saving role for millions worldwide, the stent’s journey is one of relentless innovation, failure, and breakthrough.

Arasi Maran will guide you through gripping real-life stories, incredible historical moments, and the scientific and ethical debates that shape the way stents are used today. Whether you have personal experience with heart disease or just curiosity about how these tiny devices work, you’ll come away empowered with practical knowledge and a deeper appreciation for the curious minds and persistent hearts that transform lives.

If you’ve ever wondered how a metallic mesh can change the fate of a family or what really happens when you’re told you need a stent, this episode is for you. So settle in as we explore the history, the controversies, and the future of one of medicine’s most important inventions.

00:00 Explaining what a stent is

05:10 Runner has heart attack after race

07:03 Understanding plaque and stents

10:21 Crazy Charlie's unconventional methods

14:30 Experimenting with PVC materials

20:07 Risks of traditional heart treatments

23:15 Creating the wall stent design

25:27 Early stent complications and thrombosis

30:26 Using intravascular ultrasound for stents

33:14 Using anti-cancer drugs on stents

36:16 Evolution of stent materials

38:48 Failures of dissolvable stents

44:48 When surgery is needed over stents

46:11 Trusting your cardiologist's decisions

51:09 Continuing innovation in stent development

53:14 Ending with a safety disclaimer

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Welcome to Infinite Health. Today's episode tackles one of the most critical and confusing issues facing women as they approach menopause: hormone replacement therapy (HRT). With one in three women over 50 taking HRT, questions swirl around whether it protects the heart or puts breast health at risk. To unravel the facts from the fear, Dr. Arasi Maran, a cardiologist who specializes in coronary artery disease in women and treats breast cancer survivors, giving her unique insight at the intersection of these major health concerns. Together, we’ll break down the latest evidence on HRT’s benefits and risks, debunk persistent myths, and offer a practical, personalized framework for navigating menopause with confidence. If you or someone you love is facing menopause, this is the episode you can’t afford to miss.

00:00 Specializing in women's heart health

04:08 Discussing menopause fears

06:47 Effects of menopause on body composition

11:12 Discussing bioidentical hormones

14:11 Transdermal vs. oral estrogen risks

17:59 Impact of stopping HRT on cancer risk

22:23 Breast cancer survivors and HRT discussion

24:41 HRT advice for women in 50s

28:15 Assessing risks for HRT decisions

33:10 Managing hot flashes with medication and lifestyle

35:25 Choosing the Right HRT Plan

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Everywhere you look, it seems like everyone is talking about Ozempic at dinner parties, on social media, and in the headlines. But behind the hype, confusion swirls about what these medications really are, who should be taking them, and what the risks might be. In this episode of Infinite Health, Dr. Maran will unravel the complex world of GLP-1 medications. She'll break down what GLP-1s actually do in the body, how Ozempic became a household name, and the differences between popular medications like Ozempic, Wegovy, and Mounjaro. Dr. Arasi Maran will explore the verified science and benefits, the risks and side effects that don’t make it into glossy ads, and the realities of new digital health frontiers and gray-market access. Whether you’re curious, skeptical, or just want to separate the evidence from the noise, this episode is your guide to one of medicine’s fastest-moving frontiers.

00:00 The Ozempic phenomenon explained

04:49 Discussing weight loss medications

07:47 Triple agonists and clinical trials

12:34 Discussing oral semaglutide benefits

14:17 Comparing injectable vs. pill methods

19:39 Balancing weight loss and muscle health

22:49 Side effects of weight loss meds

24:36 Safety and mindset in weight loss

27:42 Concerns about compounded peptides

33:00 India's role in metabolic health market

35:31 Risks of widespread medication use

38:32 Understanding Medications and Health Hype

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Welcome back to Infinite Health! In today’s episode, interventional cardiologist Dr. Arasi Maran dives into a topic affecting millions of women, yet often hidden in plain sight: the midlife transition, perimenopause, and menopause. Dr. Arasi Maran breaks down why women in their 40s and 50s experience symptoms like exhaustion, sleep disruption, anxiety, mood changes, and unexplained weight gain, symptoms that too often get dismissed as “just stress.”

She explores what’s really happening inside a woman’s body during this transition, from fluctuating hormones to the profound impact on cardiovascular and bone health. Along the way, they shed light on overlooked symptoms, debunk myths around weight gain, discuss the crucial role of muscle-building, and examine the latest evidence on hormone therapy. Plus, they take a global look at women’s health, comparing the midlife experience in places like India to the West.

If you’re ready for practical advice and empowering science-based insight about thriving through life’s changes, this episode is for you. Let’s dive in!

00:00 Discussing women's health issues

06:23 Understanding perimenopause symptoms in your 40s

14:22 Dealing with hormone-related symptoms

16:02 Recognizing physical signs and symptoms

22:03 Impact of estrogen loss after 40

29:37 Preventative weight training habits

36:28 Hormones impact hunger and diet

40:00 Hormone therapy and cardiovascular health

43:26 Considering hormone replacement therapy

49:20 Sleep tracking and HRV apps discussion

57:16 Understanding midlife biological changes

01:00:31 Discussing menopause and aging stigma

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Welcome to another episode of Infinite Health. What if the number that best predicts how long you'll live isn’t your blood pressure, cholesterol, or smoking status, but a metric almost no one has heard of? In this episode, cardiologist Dr. Moran uncovers the science and significance behind VO2 max, a powerful indicator that could change the way you think about exercise and longevity. Together, they explore why VO2 max matters more than traditional health markers, how you can measure and improve it from home, and what an evidence-based weekly exercise plan actually looks like, even for busy professionals. Whether you’re new to fitness or aiming to optimize your health, discover why tracking and improving VO2 max could be the most important change you make for a longer, healthier life.

00:00 VO2 max and longevity link

04:51 Understanding VO2 max and health benefits

07:50 Improving VO2 max with age

10:44 Optimizing workouts for VO2 Max

15:37 Importance of improving muscle mass

16:59 Importance of strength training

22:28 Tracking VO2 trends accurately

23:58 Understanding VO2 max levels

28:11 Morning mobility exercises overview

30:36 Heart rate apps reduce decision fatigue

35:59 Importance of exercise for health

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Imagine being told your blood sugar is normal, your labs are "fine," and yet, beneath the surface, your body has been struggling for years with a silent metabolic dysfunction. In today's episode of Infinite Health, Dr. Arasi Maran, an interventional cardiologist, to unpacks the hidden epidemic of insulin resistance, a root cause fueling heart attacks, fatty liver, dementia, and more. Despite its impact, insulin resistance is rarely screened for and often missed until it's progressed for a decade or longer. Together, we’ll cut through the noise and reveal why traditional testing fails to catch this condition early, how it connects to nearly every chronic disease of modern life, and what practical steps you can take to detect and reverse, it before it’s too late. Get ready to shift from reactive medicine to proactive health with science-backed strategies for knowing your numbers, moving your body, eating real food, and transforming your long-term well-being.

00:00 Understanding insulin resistance early

05:24 Insulin resistance and health impacts

09:08 Early detection of insulin resistance

12:01 Understanding triglyceride to HDL ratio

14:38 Calculating and interpreting Homo IR

17:10 Exercise to combat insulin resistance

21:29 Impact of ultra processed foods

26:05 Impact of stress on visceral fat

28:11 Discussion on BMI and body composition

32:27 FDA approval for CGMs in 2024

36:11 Discussing GLP1 and diabetes treatments

39:49 Key takeaways for better health

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Welcome back to Infinite Health! On today’s episode, host and cardiologist Dr. Arasi Maran dives into a topic that is both surprising and urgent: heart disease is the number one killer of women outpacing cancer, including breast cancer. Yet for most women, the risks and warning signs remain shrouded in mystery, and the medical system too often relies on research based predominantly on men.

Dr. Maran to unravels how a woman’s risk of heart disease changes dramatically across her lifespan from her very first period, through pregnancy, to perimenopause and beyond. Together, they explore why hormonal transitions are not just reproductive milestones, but critical windows that can reveal early signals of cardiovascular risk.

Whether you’re in your teens, planning a family, navigating menopause, or simply want to advocate better for the women in your life, this conversation will empower you with cutting-edge science, practical insights, and actionable steps for every stage. Heart health isn’t just a man’s issue, it’s every woman’s story. Let’s uncover what every woman needs to know, and why it’s time we all start listening to the signals our bodies are giving us.

00:00 Early childhood events and heart risks

08:47 PCOS and cardiovascular risk factors

13:38 Heart changes during pregnancy

17:35 Recognizing peripartum cardiomyopathy signs

22:01 Pregnancy-related heart attack risks

28:13 Gestational diabetes and heart risks

32:50 Effect of declining estrogen levels

38:07 Atrial fibrillation concerns for women

44:48 Understanding heart health in women

52:45 Discussing pregnancy health concerns

57:19 Advocating for women's health issues

01:00:45 Discussing women's cardiovascular health

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