This is episode 313 of MEMCast. In this week's episode we speak to Dr Meshva Amin an ST4 Geriatrics trainee on her experiences stepping up the role of medical registrar and how to navigate leading the acute medical take as a new med reg.

In this episode of MEMcast, we delve further into intrinsic renal disease, exploring the role of urine dipstick testing in differentiating intrinsic renal pathology from other causes of acute kidney injury.

We take a practical approach to interpreting urinary findings, identifying when further immunological investigations are indicated, and understanding when a kidney biopsy should be considered to establish a diagnosis and guide management.

We hope this episode will improve your understanding of intrinsic renal disease, strengthen your clinical reasoning and make your approach to investigating AKI more confident and systematic.

In this episode we discuss the key distinguishing features of eczema from other scaly rashes and work through a case of eczema herpeticum.

In this episode, we discuss key skin findings that can be clues to potential connective tissue disease. Conditions discussed include sarcoidosis, dermatomyositis and systemic lupus erythematosus.

In this episode of Memcast, we are joined by Dr Ambrose, Consultant Neurologist at Queen’s Medical Centre, Nottingham, to work through a practical approach to peripheral neuropathy.

We discuss how to phenotype neuropathy before investigating it, using the clinical history and examination to distinguish patterns such as length-dependent polyneuropathy, demyelinating and axonal neuropathies, mononeuritis multiplex, GBS, CIDP and inherited neuropathies such as Charcot–Marie–Tooth disease.

In this episode of MEMcast, we explore intrinsic kidney disease, both as a distinct disorder and as part of the continuum. We discuss how to differentiate pre-renal, intrinsic and post-renal causes of AKI, the clinical features that should raise suspicion of intrinsic renal disease, and important clues.

In this episode of MEMcast, we delve deeper into secondary hyperparathyroidism in chronic kidney disease, taking a practical approach to its investigation and management, including phosphate control, vitamin D therapy, calcimimetics and parathyroidectomy.

We also explore the key differences between primary, secondary and tertiary hyperparathyroidism, and the biochemical and clinical features that help distinguish between them.

In this episode of MEMcast, we explore secondary hyperparathyroidism in chronic kidney disease, a common but sometimes challenging complication of CKD. We break down why PTH rises as kidney function declines, explore the relationship between calcium, phosphate, vitamin D and PTH, and discuss how to recognise, investigate and manage these abnormalities in clinical practice.