In this edition, we look at frailty as a predictor of fractures, predictors of pain in rheumatoid arthritis and more.

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Frailty may predict osteoporotic fracture in US veterans with rheumatoid arthritis

Factors unrelated to inflammation may contribute to unacceptable rheumatoid arthritis pain

US House committee opens investigations into five drugmakers over clinical trials in China

Survey shows high variability in cannabis use across patients with rheumatic disease

New England Journal of Medicine retracts avacopan study used by FDA to assess efficacy

In this edition, we look at the brain-immune axis, EULAR updates and more.

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'Brain-immune axis' implicated in simultaneous inflammation and depression, mood disorders

EULAR updates physical activity recommendations for inflammatory arthritis, OA

Study demonstrates proof-of-concept for FcRn blocker nipocalimab in lupus

'Uniquely structured' izokibep improves skin, disease activity in psoriatic arthritis

Dual-target CAR T-cell therapy exhibits 'profound' remission in systemic sclerosis

References:

Calabrese L. The science of the connection: Inflammation and mental health. Presented at: EULAR 2026 Congress; June 3-6, 2026, London.

Furie RA. Abstract LB007. Presented at: EULAR 2026 Congress; June 3-6, 2026, London.

Mease PJ. Abstract OP073. Presented at: EULAR 2026 Congress; June 3-6, 2026, London.

Rausch Osthoff AK, et al. Ann Rheum Dis. 2026;doi:10.1016/j.ard.2026.03.006.

Zhang Y. Abstract OP0311. Presented at: EULAR 2026 Congress; June 3-6, 2026, London.

In this edition, we look at new EAULAR recommendations for rheumatoid arthritis, the vagal nerve and more.

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New EULAR recommendations for rheumatoid arthritis keep pace with 'ever-evolving field'

Calabrese: Vagal nerve stimulation a 'tectonic shift' in rheumatoid arthritis management

FDA grants fast track designation to intra-articular GLP-1 analog for knee osteoarthritis

Lupus prevention remains elusive despite new treatments

New agents, combinations make for 'exciting time' in psoriatic arthritis

References:

Calabrese LH. Psychoneuroimmunology 101; How will vagal nerve stimulation affect the rheumatologist's practice. Presented at The Congress of Clinical Rheumatology East; April 30-May 3, 2026; Destin, Florida (hybrid meeting).Healio interviews

Healio interviews

Healio interviews

James JA. Novel treatments for systemic lupus erythematosus. Presented at: Congress of Clinical Rheumatology East; April 30-May 3, 2026; Destin, Florida (hybrid meeting).

Kavanaugh A. Achieving precision medicine in PsA: Novel treatment strategies. Presented at The Congress of Clinical Rheumatology East; April 30-May 3, 2026; Destin, Florida (hybrid meeting).

In this edition, we look at rheumatology visits impacting reproductive health counseling, restrictive Medicare Part D coverage, and more.

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Services targeting rheumatology visits increased reproductive health counseling rates 625%

Medicare Part D coverage of certain rheumatoid arthritis drugs 'restrictive'

DMARD treatment fails to mitigate osteoporosis in rheumatoid arthritis

FDA to 'carefully shepherd' CAR T-cell therapy trials in autoimmune, rheumatic disease

Low pay, longer training requirements hobble pediatric rheumatology workforce numbers

References:

Aritomi T, et al. Arthritis Rheumatol. 2026;doi:10.1002/art.70125.

Healio interviews

Healio interviews

Kwon Y, et al. Arthritis Rheumatol. 2026;doi:10.1002/art.70132.

Marcy D, et al. Arthritis Care Res. 2026;doi:10.1002/acr.80014.

In this edition, we look at the impact of GLP-1s on total joint replacement, the safety of NSAID's and more.

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GLP-1s may have profound impact on total joint replacement

NSAID use may be safe prior to total joint arthroplasty

Complication risk may be lower for revision TJA when performed in ASC

Despite improved function, patients with elbow dislocation often report long-term pain

Osteochondral allograft transplant may treat pediatric elbow osteochondritis dissecans

References:

Acuña AJ, et al. Paper 33. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Foran JRH, et al. Paper 31. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Healio Interviews

Perkins CA, et al. Am J Sports Med. 2025;doi:10.1177/03635465251366903.

Plaisier N, et al. Paper 29. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

In this edition, immunotherapy in advanced lung cancer, updates in EGFR-mutated lung cancer and more.

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VIDEO: Immunotherapy in advanced lung cancer among highlights from ESMO 2025

VIDEO: Updates in EGFR-mutated lung cancer from ESMO 2025

VIDEO: DeLLphi-303 results show 'major jump in survival' for SCLC patients

Emphysema found during lung cancer screening raises risk for mortality

Q&A: More nonsmokers developing lung cancer due to radon exposure, air pollution

References

· González Gutiérrez J, et al. Radiology. 2025;doi:10.1148/radiol.250949.

· Healio Interviews

· Healio Interviews

· Healio Interviews

· Paulson KG, et al. Abstract OA13.01. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.

In this edition, we look at robotic-assisted surgery, dislocation risk in fixed-bearing THA and more.

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Higher head-to-cup ratio, robotic-assisted surgery may lower dislocation rate after THA

Fully maximizing bearing diameter may reduce dislocation risk in fixed-bearing THA

How may GLP-1s impact nutrition prior to orthopedic surgery?

Medicare contractors propose coverage restriction of peripheral nerve block procedures

Physician content on TikTok may guide patient education

References:

Expert submission

Healio Interviews

Healio Interviews

Kobayashi JK, et al. Paper 54. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Wang E, et al. Maximizing bearing diameter markedly lowers dislocations in primary total hip arthroplasty. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

In this edition, FDA warns complications following radiofrequency microneedling device use, chronic hand eczema considered "common" disease, and more.

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Q&A: FDA warns of radiofrequency microneedling risks; here's what to know

Chronic hand eczema now considered a 'common' skin disease in US

'Unproven' topical estrogens for the face may bring some risks

FDA approves Restylane Lyft to treat receding chin

References

Chovatiya R, et al. Prevalence of self-reported physician diagnosis of chronic hand eczema in adults: A cross-sectional study of more than 10,000 participants in the general population – Results from the CHECK study in the United States. Presented at: Fall Clinical Dermatology Conference; Oct. 23-26, 2025; Las Vegas.

Farkas E, et al J Am Acad Dermatol. 2025;doi:10.1016/j.jaad.2025.08.050.

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