In this on-location episode recorded at the RSAC Conference, Sean Martin and Marco Ciappelli sit down once again with Rob Allen, Chief Product Officer at ThreatLocker, to unpack what Zero Trust really looks like in practice—and how organizations can actually get started without feeling buried by complexity.

Rather than focusing on theory or buzzwords, Rob lays out a clear path that begins with visibility. “You can’t control what you can’t see,” he explains. The first step toward Zero Trust is deploying lightweight agents that automatically build a view of the software running across your environment. From there, policies can be crafted to default-deny unknown applications, while still enabling legitimate business needs through controlled exceptions.

The Zero Trust Mindset: Assume Breach, Limit Access

Rob echoes the federal mandate definition of Zero Trust: assume a breach has already occurred and limit access to only what is needed. This assumption flips the defensive posture from reactive to proactive. It’s not about waiting to detect bad behavior—it’s about blocking the behavior before it starts.

The ThreatLocker approach stands out because it focuses on removing the traditional “heavy lift” often associated with Zero Trust implementations. Rob highlights how some organizations have spent years trying (and failing) to activate overly complex systems, only to end up stuck with unused tools and endless false positives. ThreatLocker’s automation is designed to lower that barrier and get organizations to meaningful control faster.

Modern Threats, Simplified Defenses

As AI accelerates the creation of polymorphic malware and low-code attack scripts, Zero Trust offers a counterweight. Deny-by-default policies don’t require knowing every new threat—just clear guardrails that prevent unauthorized activity, no matter how it’s created. Whether it’s PowerShell scripts exfiltrating data or AI-generated exploits, proactive controls make it harder for attackers to operate undetected.

This episode reframes Zero Trust from an overwhelming project into a series of achievable, common-sense steps. If you’re ready to hear what it takes to stop chasing false positives and start building a safer, more controlled environment, this conversation is for you.

Learn more about ThreatLocker: https://itspm.ag/threatlocker-r974

Note: This story contains promotional content. Learn more.

Guest:

Rob Allen, Chief Product Officer, ThreatLocker | https://www.linkedin.com/in/threatlockerrob/

Resources

Learn more and catch more stories from ThreatLocker: https://www.itspmagazine.com/directory/threatlocker

Learn more and catch more stories from RSA Conference 2025 coverage: https://www.itspmagazine.com/rsac25

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Keywords:

sean martin, marco ciappelli, rob allen, zero trust, cybersecurity, visibility, access control, proactive defense, ai threats, policy automation, brand story, brand marketing, marketing podcast, brand story podcast

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