検索キーワード： 遺伝学

Brian and Deborah Charlesworth provide a clear and concise summary of the process of evolution by natural selection, and how natural selection gives rise to adaptations and eventually, over many generations, to new species. They introduce the central concepts of the field of evolutionary biology, as they have developed since Darwin and Wallace on the subject, over 140 years ago, and discuss some of the remaining questions regarding processes.

How is it that a baboon and a blob of slime mould instinctively know what to eat for optimal health, balancing their protein, fat and carb intake in perfect proportions? In new, groundbreaking research that is transforming our understanding of nutrition, animals from locusts to lions and yes, humans too, demonstrate the remarkable science behind appetite.

Racist pseudoscience is on the rise - fueling hatred, feeding nationalism, and seeping into our discourse on everything from sports to intelligence. Even the well-intentioned repeat stereotypes based on "science", because cutting-edge genetics are hard to grasp - and all too easy to distort. Paradoxically, misconceptions are multiplying amid today's unprecedented surge of research on human genetics. We've never had a clearer picture of who we are and where we come from, and the science, when accurately understood, is a powerful and definitive ally against racism.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

A biography of J. B. S. Haldane, the brilliant and eccentric British scientist whose innovative predictions inspired Aldous Huxley's Brave New World.   

The Secret Body is a gripping drama of discovery and a landmark account of the dawning revolution in human health that reveals a hitherto invisible universe within each of us.

People say that they trust scientists, yet evidence often takes a back seat to emotions. In fact, for issues that cause the loudest public furor - like vaccine safety - there is almost no debate in the scientific community. This audiobook examines the science behind today’s most contentious debates - including gun control, GMOs, and evolution, as well as strategies for understanding and coping with denialism.

Biology is undergoing a quiet but profound transformation. Several aspects of the standard picture of how life works—the idea of the genome as a blueprint, of genes as instructions for building an organism, of proteins as precisely tailored molecular machines, of cells as entities with fixed identities, and more—have been exposed as incomplete, misleading, or wrong. In How Life Works, Philip Ball explores the new biology, revealing life to be a far richer, more ingenious affair than we had guessed.

This Very Short Introduction uncovers the history of our understanding of sexual selection, from Darwin's key insights to the modern day. Considering the investment animals place on reproduction, variation in mating systems, sexual conflict, and the origin of sexual dimorphism, authors Marlene Zuk and Leigh Simmons discuss questions such as whether females can really choose between males on aesthetic grounds and how sexual conflict is resolved in different species. 

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. 

The DNA Restart, by world-renowned neurogeneticist and New York Times best-selling author Dr. Sharon Moalem, walks you through revolutionary steps to a diet and lifestyle perfect for your individual genetic makeup. The DNA Restart plan utilizes decades of in-depth scientific research into genetics, epigenetics, nutrition, and longevity to explain the pivotal role genes play in the journey to ideal weight and health status.

Genetic engineering, which refers to the direct manipulation of DNA, became a reality in the 1970s. In this audiobook, we take a look at how far the field has come, starting with a revolutionary gene-editing tool called CRISPR that’s taking the research world by storm. We then examine how CRISPR and other approaches are being investigated to treat disease, the fantastic-sounding research being done in synthetic biology, controversial efforts in modifying crops and saving species, as well as the numerous ethical issues raised in these areas.

In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development. Explaining the nature of genetic variation in the human population, how hereditary factors were identified as molecules of DNA, and how certain specific mutations can lead to disease, Slack highlights how DNA variants are used to trace human ancestry and migration, and can also be used by forensic scientists to identify individuals in crime.

Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

Unlock the secrets of your own mind! Have you ever wondered why you think the way you do, feel the way you feel, or act the way you act? "Echoes of the Past - How Evolution Shaped Your Mind" takes you on an eye-opening journey to explore the hidden, ancient forces that shape your behavior. This engaging and easy-to-understand guide explains how evolution has molded our brains for survival and reproduction.

Orphan is about the struggle to save the lives of children who, because of an unlucky roll of the genetic dice, are born with any one of several thousand rare genetic disorders. Many are burdened with diseases that carry mysterious names, some of which you will hear about for the first time in this audiobook, along with compelling stories about the physicians, scientists, and parents who have taken them on.

By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

Today, with relatively easy access to our DNA ancestry, we have more data about ourselves and family history than previous generations could have imagined. In the 12 fascinating lessons of Identity in the Age of Ancestral DNA, Anita Foeman, PhD, professor of communication and media, and founder and primary investigator of the DNA Discussion Project at West Chester University, takes us behind the scenes to examine what really happens when individuals receive their personal DNA ancestry results.