検索キーワード： 進化・遺伝学

Biology is undergoing a quiet but profound transformation. Several aspects of the standard picture of how life works—the idea of the genome as a blueprint, of genes as instructions for building an organism, of proteins as precisely tailored molecular machines, of cells as entities with fixed identities, and more—have been exposed as incomplete, misleading, or wrong. In How Life Works, Philip Ball explores the new biology, revealing life to be a far richer, more ingenious affair than we had guessed.

Carl Zimmer investigates one of the biggest questions of all: what is life? The answer seems obvious until you try to seriously answer it. Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can’t answer that question here on Earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society’s most charged conflicts - whether a fertilised egg is a living person, for example, and when we ought to declare a person legally dead. 

With acuity, humor, and respect for human diversity, The Shortest History of Sex reveals where the many facets of our sexuality—chemical, anatomical, behavioral, social—come from. Chasing down our evolutionary family tree, from the first aquatic creatures to primate societies, David Baker sheds light on our baffling array of passions, impulses, and fetishes, and guides us toward a clear understanding of one of the deepest, most abiding forces of human nature.

In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field is horizontal gene transfer (HGT), or the movement of genes across species lines. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT. In The Tangled Tree David Quammen chronicles these discoveries through the lives of the researchers who made them.

One of the biggest discoveries in physics, the quest for the Higgs boson demonstrates the value of a good theory. In July 2012, a Higgs-like particle was found near the energies scientists predicted. Now, armed with better evidence and better questions, the scientific process continues. In this audiobook, we’ve gathered our best reporting to explain that process - the theories, the search, the discovery, and the ongoing questions.

Biologist Rob Dunn reveals the crucial influence that other species have upon our health, our well-being, and our world in The Wild Life of Our Bodies - a tour through the hidden truths of nature and codependence. Dunn illuminates the nuanced relationships that exist between homo sapiens and other species, relationships that underpin humanity's ability to thrive and prosper in every circumstance. Fans of Michael Pollan's The Omnivore's Dilemma will be enthralled by Dunn's powerful, lucid exploration of the role that humankind plays within the greater web of life on Earth.

A biography of J. B. S. Haldane, the brilliant and eccentric British scientist whose innovative predictions inspired Aldous Huxley's Brave New World.   

Who are we, and how did we get here? These are two of the most fundamental and far-reaching questions facing scientists and cosmologists alike and have rested at the center of human intellectual endeavor since its beginning. They are questions that stretch across numerous disciplines. Philosophy, theology, evolutionary biology, and mathematics are just some of the fields looking to explain the emergence of human life.

Fifty thousand years ago - merely a blip in evolutionary time - our Homo sapiens ancestors were competing for existence with several other human species, just as their precursors had done for millions of years. Yet something about our species distinguished it from the pack, and ultimately led to its survival while the rest became extinct. Just what was it that allowed Homo sapiens to become masters of the planet? Ian Tattersall, curator emeritus at the American Museum of Natural History, takes us deep into the fossil record to uncover what made humans so special.  

In Venomous, molecular biologist Christie Wilcox investigates venoms and the animals that use them, revealing how they work, what they do to the human body, and how they can revolutionize biochemistry and medicine today. Wilcox takes us from the coast of Indonesia to the rainforests of Peru in search of the secrets of these mysterious animals.

Brian and Deborah Charlesworth provide a clear and concise summary of the process of evolution by natural selection, and how natural selection gives rise to adaptations and eventually, over many generations, to new species. They introduce the central concepts of the field of evolutionary biology, as they have developed since Darwin and Wallace on the subject, over 140 years ago, and discuss some of the remaining questions regarding processes.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

Cooperation is the means by which life arose in the first place. It’s how we progressed through scale and complexity, from free-floating strands of genetic material, to nation states. But given what we know about the mechanisms of evolution, cooperation is also something of a puzzle. How does cooperation begin, when on a Darwinian level, all that the genes in your body care about is being passed on to the next generation? A biologist by training, Raihani looks at where and how collaborative behavior emerges throughout the animal kingdom, and what problems it solves.

For most of us, the story of mammal evolution starts after the asteroid impact that killed the dinosaurs, but over the last 20 years, scientists have uncovered new fossils and used new technologies that have upended this story. In Beasts Before Us, paleontologist Elsa Panciroli charts the emergence of the mammal lineage, Synapsida, beginning at their murky split from the reptiles in the Carboniferous period, over 300 million years ago. They made the world theirs long before the rise of dinosaurs.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

In From Darwin to Derrida, evolutionary biologist David Haig explains how a physical world of matter in motion gave rise to a living world of purpose and meaning. Natural selection, a process without purpose, gives rise to purposeful beings who find meaning in the world. The key to this, Haig proposes, is the origin of mutable “texts”―genes―that preserve a record of what has worked in the world. These texts become the specifications for the intricate mechanisms of living beings.

 Brains Through Time examines how vertebrate nervous systems evolved in conjunction with other organ systems and the planet's ecology. Surveying an enormous range of information on genes and proteins, sensory and motor systems, central neural circuits, physiology, and animal behavior, the authors reconstruct the major changes that occurred as vertebrates emerged and then diversified. 

Australopithecines, dinosaurs, trilobites - such fossils conjure up images of lost worlds filled with vanished organisms. But in the full history of life, ancient animals, even the trilobites, form only the half-billion-year tip of a nearly four-billion-year iceberg. Andrew Knoll explores the deep history of life from its origins on a young planet to the incredible Cambrian explosion, presenting a compelling new explanation for the emergence of biological novelty.

“There is no good reason why human societies should not be described and explained with the same precision and success as the rest of nature.” Thus argues evolutionary psychologist Pascal Boyer in this uniquely innovative book. Integrating recent insights from evolutionary biology, genetics, psychology, economics, and other fields, Boyer offers precise models of why humans engage in social behaviors such as forming families, tribes, and nations, or creating gender roles. 

Without our domesticated plants and animals, human civilization as we know it would not exist. We would still be living at subsistence level as hunter-gatherers if not for domestication. It is no accident that the cradle of civilization - the Middle East - is where sheep, goats, pigs, cattle, and cats commenced their fatefully intimate associations with humans.