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Who are we, and how did we get here? These are two of the most fundamental and far-reaching questions facing scientists and cosmologists alike and have rested at the center of human intellectual endeavor since its beginning. They are questions that stretch across numerous disciplines. Philosophy, theology, evolutionary biology, and mathematics are just some of the fields looking to explain the emergence of human life.

Pandora's Lab takes us from opium's heyday as the pain reliever of choice to recognition of opioids as a major cause of death in the United States; from the rise of trans fats as the golden ingredient for tastier, cheaper food to the heart disease epidemic that followed; and from the cries to ban DDT for the sake of the environment to an epidemic-level rise in world malaria.

The Pleasure of Finding Things Out is a magnificent treasury of the best short works of Richard P. Feynman, from interviews and speeches to lectures and printed articles. A sweeping, wide-ranging collection, it presents an intimate and fascinating view of a life in science - a life like no other. From his ruminations on science in our culture to his Nobel Prize acceptance speech, this book will delight anyone interested in the world of ideas.

Winner of the Nobel Prize in Physics and author of the classic The First Three Minutes, Weinberg shares his views on some of the most fundamental and fascinating aspects of physics and the universe. But he does not seclude science behind disciplinary walls or shy away from politics, taking on what he sees as the folly of manned spaceflight, the harms of inequality, and the importance of public goods. His point of view is rationalist, realist, reductionist, and devoutly secularist.

By calling everything into doubt, Descartes laid the foundations of modern philosophy. With the celebrated words "I think therefore I am," his compelling argument swept aside ancient and medieval traditions. He deduced that human beings consist of minds and bodies; that these are totally distinct "substances"; that God exists and that He ensures we can trust the evidence of our senses.

John Forbes Nash, Jr., a prodigy and legend by the age of 30, dazzled the mathematical world by solving a series of deep problems deemed "impossible" by other mathematicians. But at the height of his fame, Nash suffered a catastrophic mental breakdown and began a harrowing descent into insanity, resigning his post at MIT, slipping into a series of bizarre delusions, and eventually becoming a dreamy, ghostlike figure at Princeton, scrawling numerological messages on blackboards.

Perhaps the greatest physicist of the second half of the 20th century, Richard Feynman changed the way we think about quantum mechanics, the most perplexing of all physical theories. Here Lawrence M. Krauss, himself a theoretical physicist and best-selling author, offers a unique scientific biography: a rollicking narrative coupled with clear and novel expositions of science at the limits.

From the moment radiation was discovered in the late nineteenth century, nuclear science has had a rich history of innovative scientific exploration and discovery, coupled with mistakes, accidents, and downright disasters.

At a time when many people around the world are living into their 10th decade, the longest longitudinal study of human development ever undertaken offers some welcome news for the new old age: Our lives continue to evolve in our later years and often become more fulfilling than before. Begun in 1938, the Grant Study of Adult Development charted the physical and emotional health of over 200 men, starting with their undergraduate days. The now-classic Adaptation to Life reported on the men's lives up to age 55 and helped us understand adult maturation.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

Mapping the Heavens provides a tour of the "greatest hits" of cosmological discoveries - the ideas that reshaped our universe over the past century. The cosmos, once understood as a stagnant place filled with the ordinary, is now a universe that is expanding at an accelerating pace, propelled by dark energy and structured by dark matter. Priyamvada Natarajan, our guide to these ideas, is at the forefront of the research - an astrophysicist who literally creates maps of invisible matter in the universe.

When a waiting world learned on April 12, 1955, that Jonas Salk had successfully created a vaccine to prevent poliomyelitis, he became a hero overnight. Born in a New York tenement, humble in manner, Salk had all the makings of a 20th-century icon - a knight in a white coat. In the wake of his achievement, he received a staggering number of awards and honors; for years his name ranked with Gandhi and Churchill on lists of the most revered people.

The discovery of the quantum - the idea, born in the early 1900s in a remote corner of physics, that energy comes in finite packets instead of infinitely divisible quantities - planted a rich set of metaphors in the popular imagination. Quantum imagery and language now bombard us like an endless stream of photons. Phrases such as multiverse, quantum leap, alternate universe, the uncertainty principle, and Schrödinger's cat get reinvented continually in cartoons and movies, coffee mugs and T-shirts, and fiction and philosophy.

How did life begin? It is perhaps the most important question science has ever asked. Over the centuries, the search for an answer has been entwined with some of science's most revolutionary advances, including van Leeuwenhoek's microscope, Darwin's theory of evolution, and Crick and Watson's unveiling of DNA.

Whether you are a scientist or a poet, pro-nuclear energy or staunch opponent, conspiracy theorist or pragmatist, James Mahaffey's books have served to open up the world of nuclear science like never before. With clear explanations of some of the most complex scientific endeavors in history, Mahaffey's new book looks back at the atom's wild, secretive past and then toward its potentially bright future.

Crystal Fire is a tale of the human factors in technology; the pride and jealousies coupled with scientific and economic aspiration that led to the creation of modern microelectronics and ignited the greatest technological explosion in history.

Why did the US intelligence services fail so spectacularly to know about the Soviet Union's nuclear capabilities following World War II? As Vince Houghton, historian and curator of the International Spy Museum in Washington, DC, shows us, that disastrous failure came just a few years after the Manhattan Project's intelligence team had penetrated the Third Reich and knew every detail of the Nazi's plan for an atomic bomb. What changed and what went wrong?

In 1910, Mary Acworth Evershed (1867-1949) sat on a hill in southern India staring at the moon as she grappled with apparent mistakes in Dante's Divine Comedy. Was Dante's astronomy unintelligible? Or was he, for a man of his time and place, as insightful as one could be about the sky? As the 20th century began, women who wished to become professional astronomers faced difficult cultural barriers, but Evershed joined the British Astronomical Association and, from an Indian observatory, became an experienced observer of sunspots, solar eclipses, and variable stars.

A sweeping account of the century of experimentation that confirmed Einstein's general theory of relativity, bringing to life the science and scientists at the origins of relativity, the development of radio telescopes, the discovery of black holes and quasars, and the still unresolved place of gravity in quantum theory.

In these brilliant essays, Lightman explores the emotional life of science, the power of imagination, the creative moment, and the alternate ways in which scientists and humanists think about the world. Along the way, he provides in-depth portraits of some of the great geniuses of our time, including Albert Einstein, Richard Feynman, Edward Teller, and astronomer Vera Rubin. Thoughtful, beautifully written, and wonderfully original, A Sense of the Mysterious confirms Alan Lightman's unique position at the crossroads of science and art.