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Medical science has made brilliant discoveries over the last century but as any cancer patient can attest, it has yet to conquer, or even fully comprehend, pain. Beginning with his own battle against severe migraines, and citing numerous case studies of his patients, in Why We Hurt Dr. Frank Vertosick explains how pain evolved, and by highlighting the critical functions it serves, he helps us to understand its value.

After the unprecedented events of the COVID-19 pandemic, it may be hard to imagine a time not so long ago when deadly diseases were a routine part of life. It is harder still to fathom that the best medical thinking at that time blamed these diseases on noxious miasmas, bodily humors, and divine dyspepsia. This all began to change on a day in April 1676, when a little-known Dutch merchant described bacteria for the first time. Ending Epidemics explains how we came to understand and prevent many of our worst infectious diseases—and double average life expectancy.

Food and Drug Administration approval for COVID-19 vaccines and the controversial Alzheimer's drug Aduhelm made headlines, but few of us know much about how the agency does its work. Why is the FDA the ultimate United States authority on a drug's safety and efficacy? In Drugs and the FDA, Mikkael Sekeres—a leading oncologist and former chair of the FDA's cancer drug advisory committee—tells the story of how the FDA became the most trusted regulatory agency in the world.

The birth of psychiatry in the early nineteenth-century fundamentally changed how madness was categorized and understood. A century on, their conceptions of mental illness continue to influence our views today. Beliefs and behavior were divided up into the pathological and the healthy. The influence of religion and the supernatural became significant measures of insanity in individuals, countries, and cultures. Troubled by Faith explores these ideas about the supernatural across society through the prism of medical history.

In Chasing the Intact Mind, Lutz traces the history of the intact mind concept, explaining how it influences current policy and practice affecting those with autism.

Mosquito Warrior tells the engrossing story of General William C. Gorgas (1854-1920), the once-renowned pioneer in tropical disease research and public health. His fascinating life illuminates vast transformations in the United States. Carol R. Byerly's balanced and contemporary examination of Gorgas illuminates his complex legacy in medicine and public health, military history, and American ambitions at the dawn of United States global ascendency.

Humankind has always wrestled with the existence of suffering. For two centuries, many American ministers, physicians, and scientists believed that an omnipotent and omniscient God created the world such that people might relieve suffering through ingenuity and learning. Others responded to the new worldview introduced by the scientific revolution as a threat to the divine order. In Imagining Progress, Kristin Johnson traces the history of Americans' evolving relationship with science and religion at "one of its most dramatic places"—the bedsides of dying children.

Doctors at War tells the stories of physicians in France working to impede the German war effort and undermine French collaborators during the Occupation from 1940 to 1945. Determined to defeat the Third Reich's incursion, one group of prominent Paris doctors founded a medical network to treat injured Resistance fighters who they then secretly transported to Allied countries to avoid forced labor in Germany. Doctors at War stands as a dramatic, character-driven account of physicians' courage and resilience in the face of evil.

Bradwel reminds us that the centenary of this apparent "wonder drug" should be no cause for celebration. Insulin often remains inaccessible to those who need it most: elusive prescriptions, uneven availability and sky-high prices result in rationing and desperate do-it-yourself research and development. In the face of bootstraps rhetoric and "Pharma Bro" capitalists, patients across the world are left to fend for themselves. There is a long way to go in the twenty-first century until insulin truly fulfills the extraordinary promises made by its discovery.

For much of recorded history, people considered the heart to be the most important organ in the body. In cultures around the world, the heart—not the brain—was believed to be the location of intelligence, memory, emotion, and the soul. Over time, views on the purpose of the heart have transformed. Modern medicine and science dismissed what was once the king of the organs as a mere blood pump subservient to the brain, yet the heart remains a potent symbol of love and health and an important part of our cultural iconography.

Intensive care units and mechanical ventilation are the crucial foundation of modern medical care: without them, the appalling death toll of the COVID-19 pandemic would be even higher. In The Autumn Ghost, Dr. Hannah Wunsch traces the origins of these two innovations back to a polio epidemic in the autumn of 1952. Drawing together testimony from doctors, nurses, medical students, and patients, Wunsch relates a gripping tale of an epidemic that changed the world.

At its core, American Disgust wrestles with how changing cultural notions of digestion-what goes into the body and what comes out of it-create and impose racial categories motivated by feelings of disgust rooted in American settler-colonial racism. It shows how disgust is a changing, yet fundamental, aspect of American subjectivity and that engaging with it-personally, politically, and theoretically-opens up possibilities for conceptualizing health at the individual, societal, and planetary levels.

In the 1970s, Dr. Alan Scott sought to selectively weaken eye muscles to treat strabismus (when one or both eyes are misaligned) without surgery. After failed attempts with other agents, Scott developed a method to stabilize the bacteria that causes botulism, culminating in a drug that eventually became known as Botox.

Long before the U.S. government began conducting secret radiation and germ-warfare experiments, and long before the Tuskegee syphilis experiments, medical professionals had introduced—and hotly debated the ethics of—the use of human subjects in medical experiments. In Subjected to Science, Susan Lederer provides the first full-length history of biomedical research with human subjects in the earlier period, from 1890 to 1940.