検索キーワード： 科学・工学

開発期間が長いバイオベンチャーの成長過程の中には「死の谷」と呼ばれる期間がある。この「死の谷」を越えるための資金調達は大変な難関で、企業存続の大きな分かれ道になる。
本誌では、バイオ後続品の「ジーンテクノサイエンス」、がん細胞を溶かす薬を目指す「オンコリスバイオファーマ」、経皮吸収製剤の「メドレックス」、細胞シート培養技術の「セルシード」をリポート。そのトップから技術・開発・成長戦略を語ってもらう。 本書は投資家向けの「会社四季報オンライン」に連載した「大化け創薬ベンチャーを探せ！」に、最新情報を加筆し電子化したものです。

Find the best solutions to your problems. Become a better decision maker. We are surrounded by systems. Businesses, schools, families, the economy, our country are all systems. The more you understand how they work, what problems do they face and how can you improve your position in them, the happier, and more stress-free your life will be. Find strategic solutions considering every aspect of your problem. Apply systems thinking to solve work, business, and relationship problems. Learn to see through the hidden pathways of contemporary politics, economics, and education changes.

If you've ever sought a job or hired someone, applied to college or guided your child into a good kindergarten, asked someone out on a date or been asked out, you've participated in a kind of market. Most of the study of economics deals with commodity markets, where the price of a good connects sellers and buyers. But what about other kinds of "goods," like a spot in the Yale freshman class or a position at Google?

Neurological and psychiatric disorders have long been regarded as fundamentally different, depending on whether they appear to affect the brain or the mind. In reality, the brain and the mind are inseparable. Both types of disorders can affect every aspect of brain function: from perception, action, memory and emotion to empathy, social interaction, attention and consciousness. It is easy to view brain disorders as simply tragic or frightening.

In Hurricane Lizards and Plastic Squid, biologist Thor Hanson tells the remarkable story of how plants and animals are responding to climate change: adjusting, evolving, and sometimes dying out. Anole lizards have grown larger toe pads, to grip more tightly in frequent hurricanes. Warm waters cause the development of Humboldt squid to alter so dramatically that fishermen mistake them for different species. Brown pelicans move north, and long-spined sea urchins south, to find cooler homes.

Smart people are not only just as prone to making mistakes as everyone else - they may be even more susceptible to them. This is the "intelligence trap", the subject of David Robson's fascinating and provocative book. The Intelligence Trap explores cutting-edge ideas in our understanding of intelligence and expertise, including "strategic ignorance", "meta-forgetfulness", and "functional stupidity."

Science fiction often takes its inspiration from the latest science . . . and our oldest questions. After all, the two are inextricably linked. At a time when advances in artificial intelligence are genuinely leading us closer to a computer that thinks like a human, we can’t help but wonder: What makes a person a person? Countless writers and filmmakers have created futuristic scenarios to explore this issue and others like it. But these scenarios may not be so futuristic after all.

In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and more.

When we think of fungi, we likely think of mushrooms. But mushrooms are only fruiting bodies, analogous to apples on a tree. Most fungi live out of sight, yet make up a massively diverse kingdom of organisms that supports and sustains nearly all living systems. Fungi provide a key to understanding the planet on which we live, and the ways we think, feel, and behave.

I am 93. I've had an extraordinary life. It's only now that I appreciate how extraordinary. As a young man, I felt I was out there in the wild, experiencing the untouched natural world - but it was an illusion. The tragedy of our time has been happening all around us, barely noticeable from day to day - the loss of our planet's wild places, its biodiversity. I have been witness to this decline.

Why can your foot move halfway to the brake pedal before you're consciously aware of danger? Why do you notice when your name is mentioned in a conversation that you didn't think you were listening to? Why are people whose name begins with J more likely to marry other people whose name begins with J? Why is it so difficult to keep a secret? Renowned neuroscientist David Eagleman navigates the depths of the subconscious brain to illuminate these surprising mysteries.

Aubrey Clayton traces the history of how statistics went astray, beginning with the groundbreaking work of the 17th-century mathematician Jacob Bernoulli and winding through gambling, astronomy, and genetics. Clayton recounts the feuds among rival schools of statistics, exploring the surprisingly human problems that gave rise to the discipline and the all-too-human shortcomings that derailed it.

We think we know photosynthesis: Plants convert of sunlight, CO2, and water into energy and, ultimately, the food we eat and air we breathe. But Raffael Jovine shows how this incredible process goes beyond what we learned in grade school. First, it's not only about plants: Corals partner with photosynthetic organisms to create the most productive habitat on Earth, slugs eat chloroplasts to create a photosynthesis-based camouflage, hornets use photosynthesis for a very unconventional form of air conditioning—and much more!

From the celebrated neurobiologist and primatologist, a landmark, genre-defining examination of human behavior, both good and bad, and an answer to the question: Why do we do the things we do? Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: He starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.

This Introduction audiobook explores emerging geological research and explains how new advances in the understanding of plate tectonics, seismology, and satellite imagery have enabled us to begin to see the Earth as it actually is: dynamic and ever-changing.

Chemistry and Our Universe: How It All Works is your in-depth introduction to this vital field, taught through 60 engaging half-hour lectures that are suitable for any background or none at all. Covering a year’s worth of introductory general chemistry at the college level, plus intriguing topics that are rarely discussed in the classroom, this amazingly comprehensive course requires nothing more advanced than high-school math. Your guide is Professor Ron B. Davis, Jr., a research chemist and award-winning teacher at Georgetown University.

The Pleasure of Finding Things Out is a magnificent treasury of the best short works of Richard P. Feynman, from interviews and speeches to lectures and printed articles. A sweeping, wide-ranging collection, it presents an intimate and fascinating view of a life in science - a life like no other. From his ruminations on science in our culture to his Nobel Prize acceptance speech, this book will delight anyone interested in the world of ideas.

In this monumental history, Vaclav Smil provides a comprehensive account of how energy has shaped society, from pre-agricultural foraging societies through today's fossil fuel-driven civilization and offers listeners a magisterial overview of humanity's energy eras.

A good book may have the power to change the way we see the world, but a great book actually becomes part of our daily consciousness, pervading our thinking to the point that we take it for granted, and we forget how provocative and challenging its ideas once were - and still are. The Structure of Scientific Revolutions is that kind of book.

There is no one better qualified than Jared Diamond - renowned expert in the fields of physiology and evolutionary biology and award-winning author - to explain the evolutionary forces that operated on our ancestors to make us sexually different. With wit and a wealth of fascinating examples, he explains how our sexuality has been as crucial as our large brains and upright posture in our rise to human status.