Democrats are looking to regain power, and there is a whole lot of warranted debate about what a winning formula looks like. “The Blueprint with Jen Psaki” is a forum where those discussions take place. On season two of her podcast, Jen sits down with some of the biggest names on the left side of the political spectrum to talk about confronting Trump 2.0 and how the Democratic party can shape the future they’d like to see.

New episodes drop October 15th. Search for “The Blueprint with Jen Psaki” to follow the show. And subscribe to MSNBC Premium on Apple Podcasts for ad-free listening.

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In the Trump-era, and within the public health narrative shaped by Robert F. Kennedy Jr., a debunked but persistent myth has taken hold: that infant vaccinations cause autism. Despite overwhelming scientific evidence disproving this claim, the narrative remains central to anti-vaccine rhetoric. Professor Richard Grinker, a cultural anthropologist and director of The George Washington University Institute for Ethnographic Research, joins Chris Hayes to examine how autism has become a political obsession, recent inflection points, what the research says about autism being underdiagnosed or overdiagnosed and more.

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A few years ago, MSNBC contributor and Pulitzer Prize-winning journalist Trymaine Lee, though healthy and only 38, nearly died of a heart attack. That experience forced him to confront the multitude of factors that almost killed him. In his new book, “A Thousand Ways to Die: The True Cost of Violence on Black Life in America,” he discusses the weight of being a Black man in America, of bearing witness, as a journalist, to relentless Black death, the toll of intergenerational oppression and more. Lee joins WITHpod to discuss three themes in the book: the long and bloody history of African Americans and guns; his work as a chronicler of gun violence and his own life story.

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The rise of AI and the development of more data centers continues to increase the need for more electricity. The electrical grid in the United States is subject to more demands than ever before. At the same time, electricity costs are not decreasing. Climate, energy and emerging tech expert Costa Samaras points out that all of this is rapidly leading to an electricity crisis. He joins Chris Hayes to discuss what’s happening now, the future outlook and what can be done.

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On September 9, 2025, Israel Defense Forces struck inside Doha targeting members of the Hamas negotiating team. With the Israeli government appearing to reject any ceasefire despite the remaining hostages in Gaza, urgent questions emerge about the future of millions of Palestinians. Amid the crisis, a new book offers some clarity and context: "Tomorrow Is Yesterday: Life, Death, and the Pursuit of Peace in Israel/Palestine" by Rob Malley and Hussein Agha. Drawing on decades of negotiations between the US, the Israeli government, and the representatives of the Palestinian people, the authors explore how we got here and what it could portend for the future. This conversation was recorded on September 10, 2025.

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Campaigns for the 2026 midterm elections are officially kicking off and candidates are starting to roll out their intro bios and platforms. One ad in particular, went viral online. It featured Graham Platner, a marine and army veteran and oyster farmer. He’s running for U.S. Senate in Maine to unseat five-term Republican Senator Susan Collins. He joins WITHpod to talk about his working class background, fault lines within the Democratic Party and more. This episode was recorded on 8/27/25.

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We are resharing this episode, which originally published on May 6th, 2025. You’ve probably seen footage or photos of people protesting the Trump regime. Some data suggests that the volume of protestors is higher than in Trump’s first term. But at the same time, you might be wondering if we’re seeing enough civil resistance to preserve American democracy. Our guest this week is one of the authors of a study that found that just 3.5% of the population taking to the streets is enough to block authoritarian takeover. Erica Chenoweth is a political scientist at Harvard. They join to discuss historical and contemporary strategies for protesting, democratic backsliding, global comparisons and more.

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Amid all of the political turmoil and global crises, one source of hope stands out: our ability to power modern life with zero emissions. Scientists warn that to limit global warming, emissions need to be cut significantly in the coming years to reach net-zero by mid-century. Bill McKibben, founder of climate justice organization 350.org and Third Act, joins WITHpod to discuss his new book "Here Comes the Sun: A Last Chance for the Climate and a Fresh Chance for Civilization," reasons he's optimistic and more.

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