Drs Ursula A. Matulonis and Immaculata De Vivo discuss the epidemiology of endometrial cancer and how clinicians can use information about risk factors.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/ca8/p04/podcast-endometrial-cancer-s3-ep6-2026a10006ig. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Endometrial Carcinoma https://emedicine.medscape.com/article/254083-overview

Cancer Stat Facts: Uterine Cancer https://seer.cancer.gov/statfacts/html/corp.html

Risk Prediction Models for Endometrial Cancer: Development and Validation in an International Consortium https://pubmed.ncbi.nlm.nih.gov/36688725/

Genome-wide Association Study of Endometrial Cancer in E2C2 https://pubmed.ncbi.nlm.nih.gov/24096698/

Projected Trends in the Incidence and Mortality of Uterine Cancer in the United States https://pubmed.ncbi.nlm.nih.gov/40589281/

Understanding Risk Factors for Endometrial Cancer in Young Women https://pubmed.ncbi.nlm.nih.gov/39235934/

Association Between Metabolic Syndrome and Endometrial Cancer Risk: A Systematic Review and Meta-analysis of Observational Studies https://pubmed.ncbi.nlm.nih.gov/32439832/

Cigarette Smoking and Endometrial Cancer Risk: Observational and Mendelian Randomization Analyses https://pubmed.ncbi.nlm.nih.gov/35900194/

Physical Activity and Risk of Endometrial Adenocarcinoma in the Nurses' Health Study https://pubmed.ncbi.nlm.nih.gov/24213924/

Hysterectomy-Corrected Uterine Corpus Cancer Incidence Trends and Differences in Relative Survival Reveal Racial Disparities and Rising Rates of Nonendometrioid Cancers https://pubmed.ncbi.nlm.nih.gov/31116674/

Type I and II Endometrial Cancers: Have They Different Risk Factors? https://pubmed.ncbi.nlm.nih.gov/23733771/

Differential Trends in Rising Endometrial Cancer Incidence by Age, Race, and Ethnicity https://pubmed.ncbi.nlm.nih.gov/36625534/

Harvard Radcliffe Institute. Podcast Episode 208: Kindness—It’s Good for You! December 12, 2024. Interview with Immaculata De Vivo and Daniel Lumera, authors of “The Biology of Kindness: Six Daily Choices for Health, Well-Being, and Longevity.” Accessed May 13, 2026. https://www.radcliffe.harvard.edu/news-and-ideas/episode-208-kindness-it-s-good-for-you

Research Project—Cooperative Agreements (U01) https://grants.nih.gov/funding/activity-codes/u01

Center for Inherited Disease Research https://cidr.jhmi.edu/

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