『The Biorevolution Podcast』のカバーアート

The Biorevolution Podcast

The Biorevolution Podcast

著者： Louise von Stechow
無料で聴く

今ならプレミアムプランが3カ月 月額99円

2026年5月12日まで。4か月目以降は月額1,500円で自動更新します。

概要

 The Biorevolution Podcast with Andreas Horchler and Louise von Stechow – father and daughter, journalist and biologist, talking about the technologies of the biorevolution. Can genetic engineering, synthetic biology, and artificial intelligence save humanity from disease, climate change, and overpopulation, or are these technologies the first step towards its downfall? Content and Editing: Louise von Stechow and Andreas Horchler Disclaimer: Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics but do not claim to give medical, investment, or life advice in the podcast. Learn more about the future of biotech in our podcasts and keynotes. Contact us here: scientific communication: https://science-tales.com/ Podcasts: https://www.podcon.de/ Image: Kelly Sikkema via Unsplash 博物学 生物科学 科学 自然・生態学
エピソード
  • AI driven protein design- beyond nature's blueprint

    AI driven protein design- beyond nature's blueprint
    2026/04/20
    Nature has “gifted” us proteins that carry out a vast array of functions in cells, shaping the lives of all organisms, ecosystems, and ultimately the planet. In the age of synthetic biology, researchers are pushing beyond the catalogue of naturally evolved proteins by redesigning or even de novo designing proteins to make them more suitable for human goals—improving function, stability, specificity, manufacturability, or even creating entirely new capabilities. Artificial intelligence is becoming an important ally in transforming protein engineering from a trial-and-error process into a more predictive discipline, where deep learning models help predict the structure and function of a novel protein directly from its sequence. This enables faster generation and optimization of sequences for desired functions and reduces expensive and time-consuming wet-lab cycles. In this episode of the BioRevolution Podcast, Louise von Stechow and Andreas Horchler speak with Ingmar Schuster, AI expert and CEO of the protein design company Provolut, about the hopes, myths, and real potential of AI in protein design. Find Imgmar here: https://www.linkedin.com/in/ingmar-schuster/ Find Provolut here: https://provolut.bio/ Learn more about how they approach protein design for their clients here:https://provolut.bio/case-study-max-planck-insitute/ Disclaimer: Louise von Stechow & Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast. Sources 1. https://www.sciencedirect.com/science/article/pii/S2590093525000177 2. https://www.nature.com/articles/s44222-025-00349-8 3. https://link.springer.com/article/10.1007/s11427-024-2906-3 4. https://pubs.acs.org/doi/10.1021/acscentsci.3c01275 5. https://www.nature.com/articles/s41586-021-03819-2 6. https://www.nature.com/articles/s41587-024-02211-5 7. https://www.science.org/doi/10.1126/science.add2187 8. https://www.nature.com/articles/s41587-024-02123-4 9. https://pubmed.ncbi.nlm.nih.gov/36702895/ 10. https://www.profluent.bio/platform 11. https://provolut.bio/case-study-max-planck-insitute/ 12. https://provolut.bio/provolut-partners-with-ginkgo-bioworks/ 13. https://biopharma.ginkgo.bio/resources/blog/ginkgo-technology-network-launches-providing-an-integrated-rd-experience-with-capabilities-from-over-25-inaugural-partners
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    34 分
  • From Animals to Algorithms: How AI Brings Drug Testing Closer to Human Biology

    From Animals to Algorithms: How AI Brings Drug Testing Closer to Human Biology
    2026/03/19
    Animal models have been the mainstay for testing hypotheses about human diseases and their treatment in academic research and drug development. However, these models raise ethical concerns and are costly and time-consuming. Most importantly, animal models often have low predictive power for the behavior of novel treatments in humans. Ethically, animal testing is arguably justifiable only if it can meaningfully predict outcomes in humans. Financially, committing millions of dollars and years of development to models with limited informative value is equally hard to defend. As governments and regulators, such as the US FDA, push to reduce animal testing, researchers from academia, pharma, and biotech are increasingly turning to new approach methodologies (NAMs) for preclinical and nonclinical testing. In this episode of the BioRevolution podcast, Louise von Stechow and Andreas Horchler discuss what is needed to shift from animal testing to NAM models which could be more meaningful for human biology. In particular, AI-based approaches offer a scalable alternative to animal testing that can make predictions based on a variety of data sources to provide a better understanding of human disease biology. Disclaimer: Louise von Stechow & Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast. Learn more about the future of biotech in our podcasts and keynotes. Contact us here: scientific communication: https://science-tales.com/ Podcasts: https://www.podcon.de/ Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow References 1. https://www.biopharmatrend.com/business-intelligence/from-animals-to-algorithms-how-ai-brings-drug-testing-closer-to-human-biology/ 2. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00298-9/fulltext 3. https://pubmed.ncbi.nlm.nih.gov/39805539/ 4. https://www.nature.com/articles/s41587-025-02690-0 5. https://www.nature.com/articles/d41586-025-03344-6 6. https://pubmed.ncbi.nlm.nih.gov/35865092/ 7. https://pubmed.ncbi.nlm.nih.gov/32868897/ 8. https://pubmed.ncbi.nlm.nih.gov/32324077/ 9. https://pubmed.ncbi.nlm.nih.gov/18357347/ 10. https://pmc.ncbi.nlm.nih.gov/articles/PMC9100373/ 11. https://pubmed.ncbi.nlm.nih.gov/31291566/ 12. https://aacrjournals.org/cancerdiscovery/article/8/9/1069/10253/Fundamental-Mechanisms-of-Immune-Checkpoint 13. https://www.nature.com/articles/s41746-025-02068-1 14. https://pubmed.ncbi.nlm.nih.gov/33356151/ 15. https://pubmed.ncbi.nlm.nih.gov/39836754/ 16. https://pubmed.ncbi.nlm.nih.gov/37676606/ 17. https://www.frontiersin.org/journals/artificial-intelligence/articles/10.3389/frai.2023.1269932/full 18. https://www.nature.com/articles/s41598-023-31169-8 19. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/vioxx-rofecoxib-questions-and-answers 20. https://onlinelibrary.wiley.com/doi/10.1002/pds.1207 21. https://www.nature.com/articles/s41467-023-42933-9
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    30 分
  • From Bench to Mic – Demystifying Science

    From Bench to Mic – Demystifying Science
    2026/03/02
    In our complex world, science can be an important guiding thread for decision-making—both for policymakers and for individuals—on how to shape the health and wellbeing of society and individuals. But science often gets lost in translation, making it hard to distinguish facts from myths and to find truth within the complex picture of modern science. Good science communication is key to demystifying science and enabling science-based decision-making for everyone. In this episode of the BioRevolution podcast, we speak with Dr. Chandni Natalia Kumar, host of the Daily Dose of Honest Science podcast, a postdoc at the Biomedical Center Munich (LMU), and a proteomics enthusiast. Through her channel, Chandni shows what it means to communicate science honestly and accessibly in a world full of hype, myths, and self-optimization trends. We explore what it takes to bridge scientific research and science communication, and discuss the power of proteomics. Find Chandni here: https://www.linkedin.com/in/dr-chandni-natalia-kumar-628b7316a/ Find the Daily Dose of Honest Science podcast on YouTube: https://www.youtube.com/@DDHS_Podcast And Spotify: https://open.spotify.com/show/0CiSf91dGsvx6LX4NGGWmH?si=9439e1dcd01f4af4 Disclaimer: Louise von Stechow & Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast. Learn more about the future of biotech in our podcasts and keynotes. Contact us here: scientific communication: https://science-tales.com/ Podcasts: https://www.podcon.de/ Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow
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    46 分
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