Peptides are everywhere—but so are questions about safety, quality, access, and regulation.

In this episode of The Synergee Podcast, Kelly and Lori welcome back Jim LaValle for an inside look at the recent FDA advisory committee discussions surrounding peptides and what they could mean for the future of peptide therapy.

Jim shares what has changed since 2023, why gray-market and research-grade peptides are such a concern, and why provider oversight, quality, and monitoring matter.

They also discuss promising uses for peptides in areas like mitochondrial health, recovery, gut health, chronic pain, muscle preservation, and healthy aging.

Plus, Jim shares his own approach to longevity—and why movement, nutrition, sleep, recovery, and lifestyle still come before peptides.

A must-listen for anyone curious about where peptide therapy is headed and how to approach it safely and responsibly.

What if just 15 minutes of exercise could help your body use oxygen more efficiently and support better energy, recovery, and healthy aging?

In this episode of the Synergee Podcast, Lori and Kelly sit down with Brad Pitzele, founder of One Thousand Roads, to explore Exercise With Oxygen Therapy (EWOT)—a modality that combines light-to-moderate exercise with breathing high-concentration oxygen to enhance oxygen delivery throughout the body.

Brad shares his personal journey through autoimmune arthritis, chronic pain, Lyme disease, and melanoma, and explains how EWOT became an important part of his healing. Together, they discuss how oxygen, microcirculation, and mitochondrial health are connected, why VO₂ max matters for longevity, and how EWOT may support exercise recovery, energy production, circulation, and healthy aging.

Whether you're looking to improve athletic performance, recover from chronic illness, or better understand the science of oxygen and resilience, this episode offers an insightful look at an emerging wellness therapy.

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If you're eating well, exercising, and doing "all the right things" but still struggling with fatigue, stubborn weight, poor sleep, brain fog, or mood changes, cortisol may be part of the missing piece.

In this episode of the Synergee Podcast, Lori Esarey and Kelly Engelman sit down with endocrinologist Dr. Jay to explore the powerful connection between cortisol and blood sugar.

They discuss how chronic stress can raise glucose, contribute to insulin resistance, disrupt sleep and hormones, and affect metabolic health. You'll also learn what continuous glucose monitors can reveal, why blood sugar variability matters, how menopause and GLP-1 medications fit into the conversation, and why lasting change requires looking beyond food alone.

This episode will change the way you think about stress, blood sugar, and your body.