The brain is messy, electric, and alive—nothing like the rigid devices we try to plug into it. But nanotech might be the missing link! This week, we unravel a review that shows how nanomaterials like carbon nanotubes and smart nanoparticles could finally let machines talk to neurons in their own language. Whether it’s sensing signals or zapping cells with magnetism, nanotech is unlocking radical new ways to interface with the mind. We also touch on "brain-on-a-chip" models and ask: just because we can, should we?

Feature paper:

https://pubs.acs.org/doi/10.1021/acsnano.4c10525?ref=feature

DNA isn’t just the stuff of life—it’s fast becoming the next-gen material for technology. In this episode, we explore how scientists are using DNA to build molecular networks, store digital data, and even reprogram plants.

You’ll hear about:

• DNA nanostructures that can solve complex problems like the Hamiltonian path

• A smart method to retrieve data evenly from DNA microchips—no deep sequencing needed

• Predictive tools that let us design genetic circuits in plants to control traits and behavior

From computing and communication to synthetic biology, DNA is stepping out of the cell and into the lab as a programmable, problem-solving tool. Welcome to the era where biology meets computation—at the molecular level.

Tạm biệt kim tiêm đau nhói, chào đón tương lai của y học – ngay trên làn da bạn! 🎉

Trong tập này, tụi mình cùng khám phá thế giới tí hon nhưng “siêu ngầu” của miếng dán vi kim – nơi khoa học vật liệu kết hợp với công nghệ phân phối thuốc thông minh. Hãy tưởng tượng chỉ một miếng dán bé xíu, không đau tí nào, lại có thể thay thế nhiều mũi tiêm vaccine, giải phóng hormone đúng nhịp sinh học của cơ thể, hay thậm chí “chuyển phát nhanh” các liệu pháp kháng thể mạnh mẽ – tất cả không cần chích một phát nào!

Nhờ vào những đột phá về sản xuất tốc độ cao, kỹ thuật “nén bột thần kỳ”, và cơ chế giải phóng thuốc lấy cảm hứng từ thiên nhiên, các nhà khoa học đang biến cách chúng ta điều trị bệnh, tăng cường miễn dịch, và chăm sóc sức khỏe mãn tính trở nên hiệu quả hơn, dễ tiếp cận hơn – và quan trọng là dễ chịu hơn cho bệnh nhân khắp thế giới.

Từ kháng thể siêu bền nhiệt đến hormone “rung đúng giờ”, vi kim tuy nhỏ mà có võ, hứa hẹn sẽ làm nên chuyện lớn trong y học hiện đại!

Nếu bạn tò mò về chuyện khoa học đã “thu nhỏ kim tiêm thành miếng dán” thế nào, thì tập này là dành cho bạn đấy!

Say goodbye to painful injections and hello to the future of medicine—right on your skin. In this episode, we dive into the tiny but mighty world of microneedle patches, where materials science meets smart drug delivery. Imagine a single, painless patch that can mimic multiple vaccine doses, release growth hormones in perfect sync with your body’s rhythm, or deliver powerful antibody therapies—all without a single jab.

Thanks to breakthroughs in high-throughput manufacturing, powder-packing wizardry, and clever bio-inspired timing, researchers are transforming how we fight disease, boost immunity, and treat chronic conditions. From thermal-stable antibodies to rhythmic hormone pulses, these microneedles are small in size but huge in potential—especially for making treatments more accessible, effective, and patient-friendly around the globe.

If you're curious about how science is shrinking syringes into stickers, this one’s for you.

Featured papers in this episode:

https://www.nature.com/articles/s41563-025-02237-3

https://doi.org/10.1038/s41551-020-00650-4

https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.2c00919

What if your next-gen energy storage tech came from...coal tar? In this episode, we dive into a game-changing study that flips the script on graphene synthesis. Scientists have discovered a low-cost, scalable way to create high-performance 3D graphene using coal tar pitch and a recyclable potassium carbonate catalyst. The result? An ultra-high surface area material with jaw-dropping capacitance—perfect for supercapacitors. We’ll unpack how this method outperforms commercial standards, explore why the ability to reuse the catalyst matters for sustainability, and geek out on why this might just be a turning point for energy tech. Buckle up—this is graphene like you’ve never seen it before.

Featured paper and patent in this episode:

https://onlinelibrary.wiley.com/doi/epdf/10.1002/smtd.202301426

https://patents.google.com/patent/US20250051167A1/en

What if electricity could flow forever—no resistance, no heat, no energy loss? In this electrifying episode of Supercool, we dive into the fascinating world of superconductors. 🚀

Join us as we trace the journey from the frosty labs of 1911, where superconductivity was first discovered, to today’s high-stakes quest for room-temperature superconductors. But here’s the twist: the new frontier isn’t just in the lab—it’s in the code. We explore how scientists are teaming up with artificial intelligence and machine learning to predict new superconducting materials, especially the elusive hydrides under extreme pressure.

We’ll break down a cutting-edge scientific review that connects the dots between old-school physics and modern-day materials informatics. From learning how critical temperature (Tc) can be predicted by algorithms to understanding the challenges of high-pressure experimentation, this episode is your backstage pass to the science shaping the future of energy and electronics.

Tune in to discover:

• Why superconductors could change the world 🌍

• How AI is becoming a lab partner 🧠🔬

• And what it will take to finally crack the code for room-temperature superconductivity

Whether you’re a curious mind or a full-on science geek, this episode will leave you feeling... supercool ❄️

Feature paper in this episode:

https://pubs.acs.org/doi/full/10.1021/acs.chemmater.4c01757

In this episode, we’re zooming in on the atomic layer deposition (ALD) of chalcogenide alloys—a breakthrough driving the future of phase change memory and ovonic threshold switches. Join us as we unravel how ALD techniques are enabling the precise creation of advanced memory materials, including innovative GeSe/GeAsSeTe heterojunctions that deliver superior performance and durability. We’ll explore why these atomic-scale processes are so crucial for next-generation memory devices, and how they’re paving the way for faster, more reliable, and energy-efficient data storage solutions. Don’t miss this deep dive into the science powering tomorrow’s smart technology!

Feature papers in this episode:

1. https://pubs.acs.org/doi/abs/10.1021/acsaelm.0c00666

2. https://pubs.acs.org/doi/full/10.1021/acsnano.9b04233

In this episode, we’re shining a light on the recent advances in material engineering for solar fuel production! Join us as we explore how scientists are making titanium dioxide (TiO₂) nanowire arrays more efficient for turning sunlight and water into clean fuel. We’ll break down how clever tweaks—like adding nitrogen and tantalum, special hydrogen and ammonia treatments, and even a boost from cobalt—help these tiny structures capture more sunlight, reduce energy loss, and speed up water splitting. Discover how these breakthroughs are bringing us closer to practical, sustainable solar energy solutions!

Featured publications in this episode:

https://pubs.acs.org/doi/full/10.1021/ja211369s

https://pubs.acs.org/doi/full/10.1021/jp309743u

https://pubs.acs.org/doi/full/10.1021/nl2028188