We’ve all heard it: dopamine is the “pleasure molecule.” Catchy, sure. But wrong. In this episode of The Cognitive Performer, Marco Rigazio unpacks the myths around dopamine and explores its real role in the brain. Far from being just about “feeling good,” dopamine is a regulator—shaping focus, working memory, and even intelligence. Along the way, you’ll discover what happens when dopamine falls out of balance (ADHD, addiction, burnout, anhedonia) and why motivation isn’t just about willpower, but about your brain’s state of readiness.

Copyright 2025 Marco Rigazio

• Molecular Imaging of Central Dopamine in Obesity: A Qualitative Review across Substrates and Radiotracers - PMC
• Age-dependent effects of protein restriction on dopamine release - PMC
• The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects - PubMed
• The tonic/phasic model of dopamine system regulation: its relevance for understanding how stimulant abuse can alter basal ganglia function - PubMed
• The tonic/phasic model of dopamine system regulation and its implications for understanding alcohol and psychostimulant craving - PubMed
• Dopamine D2/D3 receptor availability and working memory in stimulant use disorder
• Neurobiology of Schizophrenia: A Comprehensive Review - PMC
• White-Matter Integrity and Working Memory: Links to Aging and Dopamine-Related Genes - PMC
• A multi-faceted role of dual-state dopamine signaling in working memory, attentional control, and intelligence - PMC
• Dopamine-related polymorphisms and Affective Working Memory in aging - PubMed
• Effects of Caffeine Consumption on Attention Deficit Hyperactivity Disorder (ADHD) Treatment: A Systematic Review of Animal Studies - PMC
• Adult Attention-Deficit/Hyperactivity Disorder: a Narrative Review of Biological Mechanisms, Treatments, and Outcomes - PubMed
• Effects of physical exercise on children with attention deficit hyperactivity disorder - PMC
• The Cognitive-Enhancing Outcomes of Caffeine and L-theanine: A Systematic Review - PMC
• The Effects of Drugs used for the Treatment of Attention Deficit Hyperactivity Disorder (ADHD) on Pregnancy Outcome and Breast-feeding: A Critical Review - PMC
• Dezocine modulates the reinstatement of conditioned place preference in morphine-dependent rats via the dopamine reward circuitry - PMC
• From Reward to Anhedonia-Dopamine Function in the Global Mental Health Context - PMC
• Reward, motivation and brain imaging in human healthy participants – A narrative review - PMC
• Dopamine synthesis and transport:...

Ever record take after take and still feel unsure which one was right?

It might not be a creative block. It could be decision fatigue.

In this episode of The Cognitive Performer, we break down what really happens when your brain gets overloaded — and how it quietly shapes the choices you make during creative work.

You’ll learn:

• How small, invisible decisions stack up during a session
• What fatigue does to your planning, flexibility, and creative flow
• Why defaulting to “what usually works” isn’t always a good thing
• How to spot the signs of mental drain before it tanks your performance
• Simple science-backed ways to protect your energy and output

Subscribe to the newsletter for bonus content, behind-the-scenes extras, and a free glossary of neuroscience terms:

👉https://thecognitiveperformer.com

Got a question you’d like answered on the show?

Send it my way: marco@thecognitiveperformer.com

Thanks for listening — and don’t miss next month’s episode on dopamine: the buzzword, the brain chemical, and the reality behind the hype.

In this special Q&A episode, Marco answers fascinating questions from fellow voice actors about the brain and performance. Discover why people think so differently (it's actual brain wiring, not just personality), what dreams really do for your brain, and the surprising science behind "manifestation." Plus: where creativity actually comes from, what happens in your brain during those amazing "aha moments," and why exercise might be the single best thing you can do for brain health.

Topics covered: Analytical vs. holistic thinking • Dream science • Positive/negative thinking patterns • Brain aging and adaptation • The neuroscience of creativity • "Eureka moment" brain chemistry • Exercise effects on the brain

Questions from: Norm Izard (vocalnorm.com) • Monique Mosher • Erin Cox

Have a question about the brain and performance? Send a voice recording to marco@thecognitiveperformer.com

The Cognitive Performer explores the fascinating intersection of neuroscience and human performance.

• Physical Activity Lowers Brain Disease Risk - Neuroscience News
• Exercise Increases Brain Size - Neuroscience News
• Exercise-Related Physical Activity Relates to Brain Volumes in 10,125 Individuals
• Differences in psychologists’ cognitive traits are associated with scientific divides | Nature Human Behaviour
• Frontiers | Analytic and Holistic Thinkers: Differences in the Dynamics of Heart Rate Complexity When Solving a Cognitive Task in Field-Dependent and Field-Independent Conditions
• The 'middle-aging' brain
• Frontiers | Horizons in Human Aging Neuroscience: From Normal Neural Aging to Mental (Fr)Agility
• Brain-wide cell-type-specific transcriptomic signatures of healthy aging in mice
• Repetitive negative thinking is associated with amyloid, tau, and cognitive decline
• Dreaming conundrum
• Memory updating in dreams
• Unlocking Dreams and Dreamless Sleep: Machine Learning Classification With Optimal EEG Channels

Copyright 2025 Marco Rigazio