
The Anti-Inflammatory Power of Testosterone: What Human Data Tells Us About Pet Health
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In this episode, we explore the surprising and powerful link between testosterone and inflammation—and why this matters not just for humans, but for our pets too.
Drawing from peer-reviewed human studies by Mohamad et al. and Bianchi, we break down how testosterone influences pro-inflammatory cytokines, impacts adipose tissue, and plays a key role in chronic disease prevention. You’ll learn how low testosterone levels are associated with systemic inflammation and how hormone therapy in men has shown promising results in reducing markers like IL-6, TNF-α, and CRP.
So why are we talking about this on a pet health podcast?
Because pets—especially those that are spayed or neutered—also suffer from hormone deficiency and many of the same inflammation-driven conditions: arthritis, cognitive decline, obesity, and more. This episode lays the foundation for understanding how research in human endocrinology can guide integrative, evidence-based approaches to extending pet healthspan.
🔬 Key Topics Covered:
Testosterone’s role in immune modulation
The connection between fat tissue, inflammation, and hormone loss
What the human data tells us about restoring balance in neutered/spayed pets
Why this research is central to Pet Longevity Lab’s hormone-first philosophy
🎧 If you care about science-backed pet wellness, aging, and inflammation—this episode is a must-listen.
👉 Learn more at 1mpet.org