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  • Welcome to The 200 Year Life Project

    Welcome to The 200 Year Life Project
    2026/10/17

    I'm Gary Leland, I'm over 70, and I'm running a public experiment to see how long a human can live. The goal is 200.

    On The 200 Year Life Project I share everything I'm trying: the supplements I take, the workouts I do, my bloodwork and biological age tests, and what I've quit along the way. When something works, you'll hear the numbers. When it doesn't, you'll hear that too.

    You'll also hear full-length conversations with the scientists and builders working on aging, including Aubrey de Grey, Dr. Michael Roizen, Dr. Bill Andrews and Liz Parrish of BioViva.

    Follow the show so you don't miss an episode.

    More from The 200 Year Life Project
    📰 Newsletter: garyleland.substack.com
    ▶️ Watch on YouTube: youtube.com/@garyleland
    📊 My protocols, supplements and test results: GaryLeland.com
    🤝 The 200 Year Life Mastermind: GaryLeland.com/mastermind

    I am not a doctor, and I am definitely not your doctor. Nothing here is medical advice. Talk to your physician before changing anything.
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    1 分
  • Aubrey de Grey: Longevity Is Just a Side Effect of Health

    Aubrey de Grey: Longevity Is Just a Side Effect of Health
    2026/10/17

    Aubrey de Grey, the gerontologist behind the LEV Foundation and the idea of longevity escape velocity, gives us roughly a 50-50 chance of reaching it within 12 to 15 years. He doesn't call himself a longevity researcher at all: he works on health, and longer life is the side effect. At 71, I asked him what arrives first, who gets it, and what someone my age should start doing now.

    In this conversation we cover:

    • Why aging is accumulated damage, and why the body can be maintained like a machine
    • Longevity escape velocity, explained, and why 60-year-olds will get the first treatments
    • What the LEV Foundation is building, and how he got there from AI research
    • What comes first: Parkinson's, stem cells and senolytic drugs that clear zombie cells
    • Whether only the rich will get rejuvenation, and why governments will end up paying for it
    • Retirement, inheritance and the expectation shock nobody is ready for
    • The most overhyped thing in longevity
    • If you're 70, where to start: bloodwork, your genome and knowing your body

    Learn more about the LEV Foundation: levf.org

    Read the full write-up: GaryLeland.com: Aubrey de Grey Interview
    Watch the video: YouTube

    Live long and prosper,
    Gary

    More from The 200 Year Life Project
    📰 Newsletter: garyleland.substack.com
    ▶️ Watch on YouTube: youtube.com/@garyleland
    📊 My protocols, supplements and test results: GaryLeland.com
    🤝 The 200 Year Life Mastermind: GaryLeland.com/mastermind

    I am not a doctor, and I am definitely not your doctor. Nothing here is medical advice. Talk to your physician before changing anything.
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    38 分
  • Richard Rossi of DaVinci 50: The Three Fears That Stop People From Living Longer

    Richard Rossi of DaVinci 50: The Three Fears That Stop People From Living Longer
    2026/10/16

    Ask most people if they want to live to 200 and they say no before you finish the sentence. Richard Rossi, founder of the DaVinci 50 (D50) longevity mastermind, says it comes down to three fears: running out of money, running out of purpose and running out of friends. None of them is a medical problem.

    In this conversation we cover:

    • Why Richard started D50: the group he wanted to join did not exist
    • The three fears that make people say no to a longer life, and what to do about each one
    • Why he deliberately builds friendships with people decades younger
    • The "no hammer and no nail" principle, and why a mastermind should not push one doctrine
    • How D50 events are structured, and why the breaks matter as much as the speakers
    • Why he hired a judo expert to teach him how to fall

    Learn more about DaVinci 50: d50.fyi

    Read the full write-up: GaryLeland.com: Richard Rossi Interview
    Watch the video: YouTube

    Live long and prosper,
    Gary

    More from The 200 Year Life Project
    📰 Newsletter: garyleland.substack.com
    ▶️ Watch on YouTube: youtube.com/@garyleland
    📊 My protocols, supplements and test results: GaryLeland.com
    🤝 The 200 Year Life Mastermind: GaryLeland.com/mastermind

    I am not a doctor, and I am definitely not your doctor. Nothing here is medical advice. Talk to your physician before changing anything.
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    53 分
  • Saving for a Longer Life in Bitcoin: Stuart Lackey of SOUND HSA

    Saving for a Longer Life in Bitcoin: Stuart Lackey of SOUND HSA
    2026/10/16

    What if you could save for a longer life in bitcoin, with the tax advantages of a health savings account? Stuart Lackey is co-founder and CEO of SOUND HSA, an HSA that holds real bitcoin instead of cash while keeping the HSA's triple tax advantage.

    In this conversation we cover:

    • What SOUND HSA is and how the account works
    • Direct primary care, and why more people are paying their doctor directly
    • Why so many Bitcoiners take their health so seriously
    • How to think about paying for a longer life
    • Earning bitcoin for walking
    • What anyone over 65 needs to know first: once you enroll in any part of Medicare you can't add new money to an HSA, but you can keep one and spend it tax-free on qualified medical costs

    Read the full write-up: GaryLeland.com: My Interview With Stuart Lackey
    Watch the video: YouTube

    Live long and prosper,
    Gary

    More from The 200 Year Life Project
    📰 Newsletter: garyleland.substack.com
    ▶️ Watch on YouTube: youtube.com/@garyleland
    📊 My protocols, supplements and test results: GaryLeland.com
    🤝 The 200 Year Life Mastermind: GaryLeland.com/mastermind
    ⚡ Tip me in bitcoin (Lightning): garyleland@fountain.fm

    I am not a doctor, and I am definitely not your doctor, and I am not a financial or tax advisor either. Nothing here is medical, financial or tax advice. Talk to your physician and your tax professional before changing anything.
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    38 分
  • What Is Longevity Escape Velocity? Aubrey de Grey's Big Idea, Explained at 71

    What Is Longevity Escape Velocity? Aubrey de Grey's Big Idea, Explained at 71
    2026/08/19
    I am 71 years old and I intend to be the first person to reach 200. That sounds like a punchline until you understand the one idea that makes it a scientific target instead of a wish. It is called longevity escape velocity, and it is the subject of my newest video. What Is Longevity Escape Velocity? Longevity escape velocity is the point at which medicine adds more than one year of healthy life for every year that passes. Right now, aging takes a little piece of you each year and science claws some of it back, but not all of it. If that ratio ever flips, your remaining life expectancy starts rising instead of falling. You break free, the same way a rocket breaks free of Earth's gravity — which is exactly where the name comes from. It does not mean immortality. A bus can still hit you. It means aging stops being a countdown. Who Came Up With the Idea? The phrase was coined by biogerontologist Aubrey de Grey in a 2004 paper in PLoS Biology called Escape Velocity: Why the Prospect of Extreme Human Life Extension Matters Now. He had used the phrase "actuarial escape velocity" before that, and David Gobel of the Methuselah Foundation was describing much the same thing in the early 2000s. The underlying idea has been floating around life-extension circles since the 1970s. De Grey now runs the LEV Foundation, which exists to prove the concept in animals first. How Would It Actually Happen? Here is the part most people miss. It is not about slowing aging down. It is about repairing the damage as fast as it accumulates. Think of your body like a classic car. You do not drive it until it dies and leave it on the shoulder. You maintain it. You replace the worn parts. You keep it running indefinitely. In a human body, that maintenance list looks like this: Clearing senescent cells — the "zombie" cells that stop dividing, refuse to die, and poison the tissue around themRepairing mitochondria, the power plants inside your cells, which degrade with ageClearing the protein junk that builds up in the brain and is implicated in Alzheimer'sEventually, stem cell therapies and gene editing that fix damage at the source No single one of those gets you to escape velocity. The bet is that combining them does. Is Anyone Actually Testing This? Yes, in mice, right now. The LEV Foundation's Robust Mouse Rejuvenation study (RMR1) ran from 2023 to 2025 with 1,000 mice, starting treatment at roughly 18 to 19 months of age — a rough equivalent of a human in his sixties. Four interventions were tested alone and in combination. The foundation calls the result a qualified win, and I think that honesty is worth more than a headline. Combining damage repair with rapamycin did produce an additive benefit, and mean lifespan went up because more mice survived into late life. What it did not do was push out maximum lifespan — the age of the oldest survivors barely moved. That was the actual goal. RMR2 is the response: up to eight interventions instead of four, some given repeatedly rather than once, every treated group on rapamycin as a baseline, and better monitoring throughout. Same idea, more shots on goal. When Could We Reach It? Depends who you ask, and the spread is wide. The optimistic end of the field puts it at the end of this decade, around 2029 or 2030, on the back of AI-accelerated drug discovery and simulated biology. De Grey himself is more conservative, and he is the one actually running the experiments. He puts it at roughly a 50% chance within 12 to 15 years, which lands in the late 2030s, and he has been giving a version of that number for a decade without moving it much. So: somewhere between the end of this decade and the late 2030s. At 71, that gap is not academic to me. It is the whole ballgame. Why This Matters More at 71 Than at 41 If you are forty, you will almost certainly still be here when this question gets answered. If you are seventy-one, you are betting on staying healthy long enough to be a candidate for treatments that do not exist yet. That is the real reason I lift, sleep on a schedule, use the sauna, watch my markers, and write all of it down in public. The people who stay healthy enough to reach these treatments are the ones who get to use them. Everyone else misses the window by a few years and never knows how close they got. My current biological age is 56 against a chronological 71. That gap is the only thing I actually control, so I work on it every single day. My blood markers, my supplement list and my training are all on this site — the HRV numbers and the telomere experiment are two recent examples. What You Can Do Today You do not have to wait for 2029 to start. The work is unglamorous and it is available right now: Get strong — resistance training is the single most protective thing most people over 60 are not doingSleep deep, on a schedule, in a dark cold roomTest your markers so you know what is actually happening rather than how you feelStay curious and follow the ...
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    6 分
  • Dr. Michael Roizen on RealAge: Six Habits That Make Your Body Younger

    Dr. Michael Roizen on RealAge: Six Habits That Make Your Body Younger
    2026/10/16

    Dr. Michael Roizen is 80, and by his own RealAge math his body is 55. The creator of RealAge and Chief Wellness Officer Emeritus at the Cleveland Clinic says the average man can make his body about 29 years younger than his calendar age through daily choices.

    In this conversation we cover:

    • What your RealAge is, and how it differs from the age on your birth certificate
    • His top six longevity factors, in order: stress management ("posse, purpose and play"), food, avoiding unforced errors, physical activity, brain health and sleep, and preventing gum disease
    • Why daily flossing made the list, and why supplements only rank seventh
    • How a man of 80 exercises, and why he jumps every day for his spine and hips
    • Coffee, eggs, soda and sweeteners, and the 36-a-day soda habit he quit on live TV
    • Why he wants everyone to wear a glucose monitor at least once
    • Why he puts the odds of a real breakthrough in reversing aging within about seven years at 80% or better

    Dr. Roizen's new book is YOU: Getting Older, written with his wife. His free weekly newsletter is at michaelfroizenmd.substack.com.

    Read the full write-up: GaryLeland.com: Dr. Michael Roizen Interview
    Watch the video: YouTube

    Live long and prosper,
    Gary

    More from The 200 Year Life Project
    📰 Newsletter: garyleland.substack.com
    ▶️ Watch on YouTube: youtube.com/@garyleland
    📊 My protocols, supplements and test results: GaryLeland.com
    🤝 The 200 Year Life Mastermind: GaryLeland.com/mastermind

    I am not a doctor, and I am definitely not your doctor. Nothing here is medical advice. Talk to your physician before changing anything.
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    42 分
  • Dr. Bill Andrews: You Can't Live Past 125 - Until Now

    Dr. Bill Andrews: You Can't Live Past 125 - Until Now
    2026/08/06
    Everyone gets cancer every single day. According to longevity researcher Dr. Bill Andrews, the reason most of us never know is because our immune system quietly destroys these abnormal cells before they ever become dangerous. But what happens as we age? In this episode of The 200 Year Life Project, Dr. Bill Andrews—one of the world's leading experts on telomeres and founder of Sierra Sciences—explains why aging may begin with telomere shortening, how immune senescence weakens our natural defenses, why cancer risk rises with age, and what researchers are doing to slow—or potentially reverse—this process. Along the way, Bill breaks down complex longevity science using simple analogies, including ride tickets, brick walls, tug-of-war, and the famous "Betty White Test" for true age reversal. He also shares his perspective on telomerase, cancer biology, longevity escape velocity, gene therapy, Liz Parrish's work, and the future of extending healthy human lifespan. Whether you're interested in longevity, anti-aging research, telomeres, cancer prevention, or the future of regenerative medicine, this conversation offers one of the clearest explanations you'll hear. In this episode: • Why everyone develops cancer cells every day—and why most never become cancer • What telomeres actually do • The Hayflick Limit explained simply • Why aging weakens the immune system • How Bill Andrews believes aging could eventually be reversed • The "Betty White Test" • Longevity Escape Velocity • Bill's personal longevity routine ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ If this content is useful to you, do me a favor and SUBSCRIBE. It genuinely helps the channel grow and reach more people chasing a longer, healthier life. 🔬 My full longevity database — copy it, tweak it, beat us to 200: 👉 https://GaryLeland.com/data More from The 200 Year Life Project 📰 Newsletter: garyleland.substack.com ▶️ Watch on YouTube: youtube.com/@garyleland 📊 My protocols, supplements and test results: GaryLeland.com 🤝 The 200 Year Life Mastermind: GaryLeland.com/mastermind ⚕️ I'm not a doctor and I'm definitely not your doctor. Just two boomers enjoying life. Always check with your physician before trying any of my protocols. ───────────────────────────────── 👥 JOIN THE COMMUNITY ───────────────────────────────── 🔵 Free Facebook Group (start here) ▶ https://GaryLeland.com/facebook ▶ YouTube: / @garyleland ▶ X: https://X.com/garyleland ▶ Instagram: / gary_leland ▶ LinkedIn: / garyleland ▶ TikTok: / garyleland ───────────────────────────────── 💰 DISCOUNT LINKS — Products I Use Daily ───────────────────────────────── 🧬 Telo-Vital Cellular longevity support, developed with telomere scientist Dr. Bill Andrews. ▶ https://GaryLeland.com/Telo 🕶️ TrueDark Glasses I wear these every evening starting 2 hours before bed to block junk light. Save 10% on first order ▶ https://GaryLeland.com/Truedark 👂 Loop Earplugs I wear these so noise doesn't wake me up. ▶ https://GaryLeland.com/Loop 🛏️ GroundLux Grounding Sheets Kathy & I sleep on these every night — we even take our pillowcases on the road. Save 10% — code Leland10 ▶ https://GaryLeland.com/sheets 💧 Vinia Blood Flow Hydration First thing I drink every morning as soon as I wake — great for heart health. Save 17.5% ▶ https://GaryLeland.com/Vinia 🦷 Cardio Smile Toothpaste Fluoride-free and a great way to increase Nitric Oxide. ▶ https://GaryLeland.com/toothpaste 💪 Jawzrsize Jaw training to tighten my jaw and neckline. Save 20% ▶ https://GaryLeland.com/jawzrsize ⚖️ Hume Body Pod Body composition scale — tracks muscle, fat, and metabolic age, not just weight. Save 20% ▶ https://GaryLeland.com/Hume ☕ Blueprint Cocoa Powder I add a spoonful to my morning coffee every single day since August 2025. Save $20 + FREE Shipping on 1st Order ▶ https://GaryLeland.com/Cocoa ☕ Danger Coffee Premium performance coffee. I drink 4 cups every day. Save 10% — code GARYL ▶ https://GaryLeland.com/Coffee ⚡ Qitone Ketone Powder Flavorless ketone powder for clean energy, mental clarity, and brain health. Code Gary15 ▶ https://qitone.com 💍 Ultrahuman Ring Air I wear this 24/7 to track sleep, recovery, and activity — no monthly subscription. ▶ https://GaryLeland.com/Ring 🩸 Function Health Know your numbers — 160+ lab tests screening for 1,000+ conditions. ▶ https://GaryLeland.com/Function ───────────────────────────────── 📌 Affiliate Disclosure: The ...
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    53 分
  • We're 71 and We Just Joined a Secret "Live to 200" Mastermind

    We're 71 and We Just Joined a Secret "Live to 200" Mastermind
    2026/06/09

    Kathy and I are 71 and we just spent days in a room full of doctors and scientists who believe aging is optional. This is what happened at the DaVinci50 Longevity Mastermind in Sundance, Utah, and the two decisions it pushed us to make on our way to 200. We didn't know what to expect at our very first mastermind. We left as members and already booked our full genome sequencing.

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    🎙️ HERE'S WHO LIT A FIRE UNDER US.

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    🧬 Elizabeth Parrish (CEO, BioViva) the first person in the world to undergo experimental gene therapy targeting aging itself, including telomere extension. Her message: turn belief into biology.

    🩺 Michael Roizen, M.D. (Cleveland Clinic, creator of "RealAge") practical, evidence-based steps you can start today: 10,000 steps, strength training, jumping for bone health, and smart nutrition.

    ⚡ Harry Massey (founder, NES Health) a whole new lens on health through bioenergetics and the human body-field.

    🔬 Wei-Wu He, Ph.D. (Executive Chairman, Human Longevity, Inc.) catching cancer and age-related disease years before symptoms with genomic sequencing and AI.

    ─────────────────────────────────

    Founded by Richard Rossi, DaVinci50 is an invite-only community pushing real rejuvenation science gene therapy, stem cells, genomics, bioenergetics into use now, instead of waiting decades.

    If this content is useful to you, do me a favor and SUBSCRIBE. It genuinely helps the channel grow and reach more people chasing a longer, healthier life.

    🔬 My full longevity database — copy it, tweak it, beat us to 200: 👉 https://GaryLeland.com/data

    💬 Your turn: Have you ever been to a mastermind? What's one big longevity idea you're acting on right now? Drop it in the comments, I read every one.

    More from The 200 Year Life Project
    📰 Newsletter: garyleland.substack.com
    ▶️ Watch on YouTube: youtube.com/@garyleland
    📊 My protocols, supplements and test results: GaryLeland.com
    🤝 The 200 Year Life Mastermind: GaryLeland.com/mastermind

    ⚕️ I'm not a doctor and I'm definitely not your doctor. Just two boomers enjoying life. Always check with your physician before trying any of my protocols.

    #200YearLife #Longevity #DaVinci50 #GeneTherapy #ElizabethParrish #HealthSpan #Biohacking #AntiAging #GaryLeland #LiveTo200

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    💰 DISCOUNT LINKS — Products I Use Daily

    ─────────────────────────────────

    🕶️ TrueDark Glasses I wear these every evening starting 2 hours before bed to block junk light. ▶ https://GaryLeland.com/Truedark

    🛏️ GroundLux Grounding Sheets Kathy & I sleep on these every night — we even take our pillowcases on the road. ▶ https://GaryLeland.com/sheets

    💧 Vinia Blood Flow Hydration First thing I drink every morning as soon as I wake — great for heart health. ▶ https://GaryLeland.com/Vinia

    🦷 Cardio Smile Toothpaste Fluoride-free and a great way to increase Nitric Oxide. ▶ https://GaryLeland.com/toothpaiste

    💪 Jawzrsize — Save 20% Jaw training to tighten my jaw and neckline. ▶ https://GaryLeland.com/jawzrsize

    ☕ Blueprint Cocoa Powder — Save $20 + FREE Shipping on 1st Order I add a spoonful to my morning coffee every single day since August 2025. ▶ https://GaryLeland.com/Cocoa

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    📌 Affiliate Disclosure: The links above are affiliate links, meaning I may earn a small commission if you purchase — at no extra cost to you. I only recommend products I personally use. Thank you for supporting The 200 Year Life Project! ────────────────────────────────
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    4 分