S2 Episode 1: What's Next? Clinical Trials in Myelofibrosis
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S2 Episode 1: What's Next? Clinical Trials in Myelofibrosis
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このコンテンツについて
Drs Tania Jain and Ruben Mesa discuss the clinical trials and the future of myelofibrosis research.
Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002053. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Myeloproliferative Neoplasms (MPNs) Have a Significant Impact on Patients’ Overall Health and Productivity: The MPN Landmark Survey https://pubmed.ncbi.nlm.nih.gov/26922064/
A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis https://pubmed.ncbi.nlm.nih.gov/22375971/
The Myelofibrosis Symptom Assessment Form (MFSAF): An Evidence-Based Brief Inventory to Measure Quality of Life and Symptomatic Response to Treatment in Myelofibrosis https://pubmed.ncbi.nlm.nih.gov/19250674/
Practical Measures of Clinical Benefit With Ruxolitinib Therapy: An Exploratory Analysis of COMFORT-I https://pubmed.ncbi.nlm.nih.gov/28606598/
The Myeloproliferative Neoplasm Symptom Assessment Form (MPN-SAF): International Prospective Validation and Reliability Trial in 402 Patients https://pubmed.ncbi.nlm.nih.gov/21536863/
Randomized, Single-Blind, Multicenter Phase II Study of Two Doses of Imetelstat in Relapsed or Refractory Myelofibrosis https://pubmed.ncbi.nlm.nih.gov/34138638/
Phase III MANIFEST-2: Pelabresib + Ruxolitinib vs Placebo + Ruxolitinib in JAK Inhibitor Treatment-Naive Myelofibrosis https://pubmed.ncbi.nlm.nih.gov/35950489/
Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis (TRANSFORM-2) https://clinicaltrials.gov/study/NCT04468984
Allogeneic Stem Cell Transplant for Patients With Myeloproliferative Neoplasms in Blast Phase: Improving Outcomes in the Recent Era https://pubmed.ncbi.nlm.nih.gov/33821472/
Efficacy and Safety of Ruxolitinib After and Versus Interferon Use in the RESPONSE Studies https://pubmed.ncbi.nlm.nih.gov/29396713/