In this episode of Plants of the Gods, ethnobotanist Dr. Mark Plotkin takes us on a sweeping journey through the epic history of the spice trade—one of the most transformative chapters in global history. From ancient trade routes and religious rituals to colonial conquests and modern capitalism, spices like cinnamon, pepper, nutmeg, and cloves have shaped agriculture, medicine, navigation, and even warfare. Dr. Plotkin also reviews Roger Crowley's gripping new book, Spice: The 16th-Century Contest That Shaped the Modern World.

Ethnobotanist Dr. Mark Plotkin discusses Brugmansia, some of the most beautiful hallucinogenic plants in the botanical world. Their bright flowers hang like sacred trumpets and have long been used by traditional healers of the Andes-Amazon region as an important component of their medicine chest. Closely related to the 'hexing herbs' of European witches of the Middle Ages (as detailed in an earlier episode), these fascinating plants can heal - or harm.