So far, immunotherapy has been a game-changer in other cancers but not pancreatic cancer. Is that finally changing?

In this episode of PancChat, host Alisyn Camerota sits down with Dr. Elizabeth Jaffee, deputy director of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins and chief medical advisor of the Lustgarten Foundation. Dr. Jaffee breaks down the science behind pancreatic cancer's resistance to immunotherapy, the promise of cancer vaccines, and the emergence of KRAS inhibitors as a new class of targeted therapies. After thirty years in the field, she shares why she is more optimistic than ever.

PancChat is a collaboration between Let's Win Pancreatic Cancer and PanCAN.

In this episode of PancChat, host Alisyn Camerota sits down with Dr. Vinod Balachandran, a surgeon-scientist at Memorial Sloan Kettering Cancer Center and the founding director of the Olayan Center for Cancer Vaccines, to take a closer look at vaccines being developed to prevent recurrence of pancreatic cancer.

Dr. Balachandran breaks down three promising vaccine approaches currently in development — including the mRNA vaccine his team is working on — and explains how each one works, who may be eligible for clinical trials, and why progress in pancreatic cancer could have implications for other cancer types as well.

PancChat is a collaboration between Let's Win Pancreatic Cancer and PanCAN. Find us wherever you listen to podcasts.

Learn More:

Let's Win Pancreatic Cancer

Pancreatic Cancer Action Network (PanCAN)

Let's Win Clinical Trial Finder

PanCAN Clinical Trial Finder

PanCAN Patient Services

Pancreatic enzyme replacement therapy — known as PERT — may be one of the most important yet overlooked tools for pancreatic cancer patients and survivors. In this episode of PancChat, host Alisyn Camerota sits down with Dallas Lawry, an advanced oncology certified nurse practitioner at UC San Diego Moores Cancer Center, to break down why up to 90% of pancreatic cancer patients experience exocrine pancreatic insufficiency, how PERT works, and practical tips for getting the most out of treatment — including how to time doses with meals, navigate insurance coverage, and explore alternatives when costs become a barrier.

PancChat is a collaboration between Let’s Win Pancreatic Cancer and PanCAN. Find us wherever you listen to podcasts.

Learn More:

• Canopy Collective EPI Pert White Paper
• Let's Win Pancreatic Cancer
• Pancreatic Cancer Action Network (PanCAN)
• Let's Win Clinical Trial Finder
• PanCAN Clinical Trial Finder
• PanCAN Patient Services