Stop Guessing: Your Genes Reveal the Best Diet & Workout

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Dr. Sam Shay - Genetics Testing

FitGenesUSA.com

DrSamShay.com

In this episode of Over 40 Fitness Hacks, I sit down with returning guest Dr. Sam Shay, Functional Medicine Certified Practitioner and Western Hemisphere Director of FitGenes USA, to explore the latest advancements in genetic testing for health, fitness, and longevity. Building on our previous conversation about the "10 Pillars of Health," Dr. Shay explains why genetic testing provides the blueprint for making smarter decisions about nutrition, exercise, recovery, and biohacking.

Dr. Shay discusses how most genetic reports overwhelm people with hundreds of confusing data points, while FitGenes focuses on prioritizing the most actionable genes related to inflammation, mitochondrial function, detoxification, vitamin D metabolism, methylation, cardiovascular health, and fat metabolism. Instead of generating information overload, the goal is to provide clear lifestyle recommendations that have the greatest impact.

We also dive into one of the most fascinating aspects of the conversation: using genetics to determine your ideal diet. Dr. Shay explains how copy number analysis of the AMY1 gene can reveal whether your body is naturally better suited for a ketogenic, paleo, Mediterranean, or higher-carbohydrate diet. He shares how discovering his own genetic carb tolerance dramatically improved his energy, digestion, mood, and overall health after years of following the wrong eating plan.

Beyond nutrition, we discuss how genetics can guide exercise programming by identifying whether you're genetically predisposed for endurance or power training, your risk for exercise-induced inflammation, collagen strength, injury susceptibility, and recovery needs. Dr. Shay emphasizes that many people unknowingly overtrain simply because they're following popular fitness trends instead of training according to their genetic blueprint.

Dr. Shay also gives viewers an inside look at the redesigned FitGenes reports, showing how they summarize key recommendations on a single page—including ideal diet, top nutrient priorities, exercise type, recovery strategies, and food sensitivities—making the information practical for both practitioners and everyday users.

Throughout our discussion, we talk about why genetics should be one of the first investments for anyone interested in biohacking or longevity. Unlike other health metrics that change over time, your DNA never changes, making genetic testing a lifelong roadmap that can help guide future lab work, supplementation, nutrition, and training decisions.

If you're interested in personalized health optimization and want to stop guessing which diets, supplements, or exercise programs are right for you, this episode provides an excellent introduction to how genetic testing can help create a personalized blueprint for lifelong health and performance.

If you're interested in online personal training or being a guest on my podcast, "Over 40 Fitness Hacks," you can reach me at brad@over40fitnesshacks.com or visit my website at:

Over40FitnessHacks

Additionally, check out my Yelp reviews for my local business, Evolve Gym in Huntington Beach, at https://bit.ly/3GCKRzV

Disclaimer: The information provided on this podcast, including interviews and recommendations, is for educational and entertainment purposes only. It does not constitute medical, nutritional, or professional fitness advice. The hosts and guests are not your personal doctors or trainers. Always consult a qualified medical professional before changing your diet, starting a new exercise regimen, or implementing any advice heard on this show. Use of any information provided is solely at your own risk.

The Longevity World Cup: Competing to Stay Young

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Founder Adam: Longevity World Cup

LongevityWorldCup.com

Instagram: @longevityworldcup

Podcast Summary: Brad Williams Interviews Adam, Developer of the Longevity World Cup

In this episode of Over 40 Fitness Hacks, Brad Williams sits down with Adam, the developer of the Longevity World Cup, to explore the emerging world of longevity, biological aging, and the idea of turning health optimization into a competitive sport.

Adam explains how his journey into longevity began after building and exiting a successful software company. Inspired by the idea that longevity could be the next major technological revolution, he began looking into the field and quickly realized there was a major problem: scientists still don't have an easy way to determine whether an anti-aging intervention is actually working without waiting decades to see whether people live longer.

That problem led Adam to a unique idea—treat longevity like a sport. The concept behind the Longevity World Cup is to create a competitive environment where people track their biological age and health markers, experiment with different interventions, and compete to improve their results. Adam believes that the people who perform best in this competition could become some of the earliest adopters of new longevity technologies, treatments, and strategies that actually work.

A major part of the conversation focuses on biological aging clocks and how they attempt to estimate a person's biological age based on health data. Brad discusses his experience with tools such as WHOOP and the growing popularity of biological-age measurements, while Adam explains the limitations of current approaches. He argues that simply determining how old someone "looks" based on their biomarkers isn't necessarily the same as measuring how healthy or resilient they actually are. Ideally, biological aging clocks should be connected to meaningful outcomes such as health, performance, and ultimately mortality.

Adam explains that this is one of the biggest challenges facing longevity research. Researchers need better biological aging clocks so they can determine whether an intervention is working without having to wait for people to die decades later. If scientists can develop reliable ways to measure biological aging, it could dramatically accelerate the pace of longevity research.

If you're interested in online personal training or being a guest on my podcast, "Over 40 Fitness Hacks," you can reach me at brad@over40fitnesshacks.com or visit my website at:

www.Over40FitnessHacks.com

Additionally, check out my Yelp reviews for my local business, Evolve Gym in Huntington Beach, at https://bit.ly/3GCKRzV

Disclaimer: The information provided on this podcast, including interviews and recommendations, is for educational and entertainment purposes only. It does not constitute medical, nutritional, or professional fitness advice. The hosts and guests are not your personal doctors or trainers. Always consult a qualified medical professional before changing your diet, starting a new exercise regimen, or implementing any advice heard on this show. Use of any information provided is solely at your own risk.

The Ultimate Health Assessment: 400 Biomarkers That Could Save Your Life

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Dr. Clint Phillips - Medici

Medici Website:

Personal Website:

Instagram: @medicihealth

Dr. Gabi App

In this episode of Over 40 Fitness Hacks, host Brad Williams sits down with Dr. Clint Phillips, founder of Medici Health, to discuss the future of personalized medicine, AI-driven health optimization, peptides, and preventative healthcare.

Dr. Phillips shares his deeply personal journey into longevity science, explaining how losing multiple family members at a young age inspired him to dedicate his career to helping people live longer, healthier lives. After building a successful chiropractic and rehabilitation practice in Aspen, Colorado, and later co-founding a medical second-opinion company following his daughter's stroke, he launched Medici Health with one mission: prevent disease before it starts.

The conversation dives into Medici's comprehensive annual health assessment, which collects over 400 health data points through advanced blood testing, DNA analysis, DEXA scans, vascular imaging, skin AI analysis, cancer screening, balance testing, and more. Rather than treating disease after it develops, Medici focuses on identifying each person's unique risk factors and creating highly personalized strategies based on genetics, biomarkers, and lifestyle.

Brad and Dr. Phillips discuss why personalized medicine is replacing the "one-size-fits-all" approach to health, highlighting examples where simple lifestyle changes—guided by genetic testing—can dramatically reduce disease risk. They also explore the growing role of artificial intelligence in healthcare, including Medici's AI assistant, Dr. Gabby, which helps users interpret health data, evaluate supplements, scan food products, and even estimate cardiovascular risk using only a smartphone camera.

The discussion also covers the rapidly growing field of peptides. Dr. Phillips explains why peptides show tremendous promise for longevity and recovery but emphasizes that they should always be paired with proper laboratory monitoring rather than taken blindly. Brad agrees that objective testing is essential since feeling better doesn't always mean your body is responding positively.

Throughout the interview, both emphasize that true health isn't simply avoiding illness—it's building resilience through exercise, nutrition, preventative testing, personalized care, and consistent habits. Dr. Phillips also praises personal trainers as some of the most influential professionals in preventive healthcare, reinforcing Brad's philosophy that fitness coaching remains one of the best investments people over 40 can make.

Whether you're interested in biohacking, longevity, AI-powered healthcare, preventative medicine, or simply maximizing your healthspan, this episode provides an insightful look at where the future of healthcare is heading and how personalized data may soon replace generic health advice.

If you're interested in online personal training or being a guest on my podcast, "Over 40 Fitness Hacks," you can reach me at brad@over40fitnesshacks.com or visit my website at:

www.Over40FitnessHacks.com

Additionally, check out my Yelp reviews for my local business, Evolve Gym in Huntington Beach, at https://bit.ly/3GCKRzV

Disclaimer: The information provided on this podcast, including interviews and recommendations, is for educational and entertainment purposes only. It does not constitute medical, nutritional, or professional fitness advice. The hosts and guests are not your personal doctors or trainers. Always consult a qualified medical professional before changing your diet, starting a new exercise regimen, or implementing any advice heard on this show. Use of any information provided is solely at your own risk.

Over 40? Your Body Is Losing This Critical Molecule Every Day

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Dr. Luke Bucci - Juvenon Supplements

www.Juvenon.com

In this episode of Over 40 Fitness Hacks, host Brad Williams sits down with Dr. Luke Bucci, Chief Scientific Officer at Juvenon Supplements, to discuss one of the biggest challenges facing adults over 40: declining energy, metabolism, and overall vitality.

Dr. Bucci shares his fascinating journey into the supplement industry, beginning with his early exposure to pathology through his father and eventually becoming a leading researcher in nutrition and longevity science. Together, Brad and Dr. Bucci explore how aging impacts the body's ability to produce nitric oxide, a critical molecule responsible for blood flow, exercise performance, brain function, and cellular health.

The conversation dives deep into:

• Why nitric oxide production naturally declines with age

• How poor lifestyle habits accelerate that decline

• The role of blood flow in energy levels, exercise performance, and recovery

• The differences between common nitric oxide supplements such as arginine, citrulline, and newer arginine-silicate technologies

• Why plant-based polyphenols and vegetables play a key role in supporting vascular health

  
  

Brad and Dr. Bucci also examine the importance of mitochondria—the tiny energy-producing structures inside every cell. Dr. Bucci explains how mitochondria respond to exercise, nutrition, and supplementation, while Brad shares practical strategies he uses with his over-40 clients to stimulate mitochondrial growth through strength training, cardio, and high-intensity interval training.

Additional topics include:

• CoQ10 and ubiquinol for cellular energy production

• Acetyl-L-carnitine and its role in fat metabolism

• The benefits of strategic intermittent fasting

• Why moderate stress can be beneficial for long-term health

• The importance of maintaining muscle mass as we age

  
  

Toward the end of the episode, Dr. Bucci highlights a frequently overlooked area of aging: joint health. He explains why cartilage repair takes years rather than months and discusses the long-term research supporting glucosamine and chondroitin supplementation for maintaining healthy joints and mobility.

This episode is packed with science-backed insights and practical strategies designed to help adults over 40 improve energy, preserve muscle, support cardiovascular health, and maintain an active lifestyle for decades to come.

Key Takeaway: Aging may be inevitable, but declining energy and performance don't have to be. By supporting blood flow, mitochondrial function, exercise consistency, proper nutrition, and joint health, it's possible to significantly improve how you feel and perform well into your later years.

If you're interested in online personal training or being a guest on my podcast, "Over 40 Fitness Hacks," you can reach me at brad@over40fitnesshacks.com or visit my website at:

www.Over40FitnessHacks.com

Additionally, check out my Yelp reviews for my local business, Evolve Gym in Huntington Beach, at https://bit.ly/3GCKRzV

Disclaimer: The information provided on this podcast, including interviews and recommendations, is for educational and entertainment purposes only. It does not constitute medical, nutritional, or professional fitness advice. The hosts and guests are not your personal doctors or trainers. Always consult a qualified medical professional before changing your diet, starting a new exercise regimen, or implementing any advice heard on this show. Use of any information provided is solely at your own risk.

Your Skin Is Telling You Something: The Longevity Warning Signs After 40

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Dr. Sofia Din - Anti Aging/Skincare

Website: https://www.sofiadinmd.com/

Podcast: Bathroom Diaries

In this episode of the Over 40 Fitness Hacks podcast, Brad Williams sits down with anti-aging expert and former geriatrician Dr. Sofia Dinh to discuss medical-grade skincare, longevity, and what really happens to the body after 40. Dr. Dinh explains the concept of “the pause” — the metabolic and hormonal slowdown that affects both men and women as they age — and why the fitness, nutrition, and skincare strategies that worked in your 20s and 30s often stop working in your 40s and beyond.

The conversation dives into how skin health is deeply connected to overall wellness, gut health, hormones, sleep quality, and even brain function. Dr. Dinh shares why the skin is often the first visible sign of aging and internal dysfunction, and how medical-grade skincare, peptides, hormone optimization, infusions, and lifestyle changes can help extend both lifespan and healthspan.

Brad and Dr. Dinh also explore the growing role of AI in health and wellness, the dangers of blindly following trendy biohacking advice, and why personalized guidance from experienced practitioners is critical. They discuss common mistakes people over 40 make — including poor sleep habits, excessive alcohol consumption, misuse of NAD boosters, and ignoring early metabolic warning signs like weight gain, insulin resistance, and low energy.

Throughout the episode, Dr. Dinh emphasizes the importance of prevention, consistency, and proactive health management before major disease develops. Listeners will learn practical strategies for improving longevity, protecting cognitive function, optimizing recovery, and recognizing when it may be time to move beyond basic supplements into more advanced medical-grade interventions.

If you’re over 40 and noticing changes in energy, body composition, skin quality, sleep, or overall vitality, this episode offers an eye-opening look at how aging affects the entire body — and what you can do to stay healthier, stronger, and more resilient for decades to come.

If you're interested in online personal training or being a guest on my podcast, "Over 40 Fitness Hacks," you can reach me at brad@over40fitnesshacks.com or visit my website at:

www.Over40FitnessHacks.com

Additionally, check out my Yelp reviews for my local business, Evolve Gym in Huntington Beach, at https://bit.ly/3GCKRzV

Disclaimer: The information provided on this podcast, including interviews and recommendations, is for educational and entertainment purposes only. It does not constitute medical, nutritional, or professional fitness advice. The hosts and guests are not your personal doctors or trainers. Always consult a qualified medical professional before changing your diet, starting a new exercise regimen, or implementing any advice heard on this show. Use of any information provided is solely at your own risk.

Using AI for Physical Therapy: What Worked and What Didn’t

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In this episode, Brad Williams shares his personal experience using AI as a tool for self-guided physical therapy, highlighting both its potential and its limitations. Drawing from years of dealing with chronic injuries, he focuses on two main issues: a long-term lower back problem and more recent knee pain.

For his back, Brad explains he’s been managing the effects of a herniated disc and multiple surgeries for nearly eight years, getting himself to about “93%” recovery through consistent routines and experimentation. Seeking that final improvement, he turns to AI for new ideas—specifically exploring sleep positioning, which he believes is the biggest trigger for his pain. AI recommends a “zero gravity” sleeping setup to reduce spinal pressure. Instead of investing in an expensive adjustable bed, Brad improvises with affordable wedges and pillows. The result is a noticeable improvement, bringing him close to “98%” recovery, making this a clear success story where AI offered a novel, effective solution he hadn’t tried before.

He then tests AI on a different issue—chronic knee pain. The AI suggests muscle imbalances, particularly involving the VMO (inner quad), and provides exercises targeting strength, stability, and mobility. While some of these recommendations align with his training style and initially help, his progress stalls and one knee worsens. Eventually, Brad consults a physical therapist, who identifies tightness in his IT band and quads as key contributors—something the AI did not emphasize. With targeted treatment like foam rolling and specific strengthening exercises, his knee pain resolves within weeks.

Brad concludes that AI can be a valuable, low-risk tool for exploring ideas, learning, and improving routines—especially for those with experience in fitness. However, it still falls short of replacing hands-on expertise and nuanced diagnosis from professionals. He emphasizes that better input and more detailed feedback to AI could improve its usefulness, but ultimately sees it as a supplement rather than a substitute for qualified care.

If you're interested in online personal training or being a guest on my podcast, "Over 40 Fitness Hacks," you can reach me at brad@over40fitnesshacks.com or visit my website at:

www.Over40FitnessHacks.com

Additionally, check out my Yelp reviews for my local business, Evolve Gym in Huntington Beach, at https://bit.ly/3GCKRzV

Disclaimer: The information provided on this podcast, including interviews and recommendations, is for educational and entertainment purposes only. It does not constitute medical, nutritional, or professional fitness advice. The hosts and guests are not your personal doctors or trainers. Always consult a qualified medical professional before changing your diet, starting a new exercise regimen, or implementing any advice heard on this show. Use of any information provided is solely at your own risk.