Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. I hope you are all enjoying the summer and that your IT treats you well. In this podcast, we have two new studies to think about.

First, should children with gastroenteritis be given anti-emetics? Would ondansetron help and improve outcomes?

Second, can methotrexate help knee osteoarthritis? It would be great if this would work, but hope only gets us so far. What does the research show?

References

NEJM Ondansetron in GE in kids

JAMA Int Med Methotrexate and knee OA

www.nbmedical.com/podcast

Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. While everyone tries to unpick the new NHS 10-year plan, we focus on the here and now with three new pieces of research.

We kick off with two gems in the BJGP - first, examining whether anti-depressants actually help with insomnia, and second, whether anti-depressants cause postural hypotension in older people, and which may be the worst. Finally, we look at a good news story, with data publishing on a new treatment for cancers linked to mismatch repair genes.

References

BJGP Insomnia paper

BJGP Anti-Ds and postural hypotension paper

NEJM dMMR gene cancer therapy

www.nbmedical.com/podcast

Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. In this episode, we look at three new pieces of research with implications for general practice.

Firstly, can exercise prevent the recurrence of colorectal cancer? Short answer, yes. But how much exercise did you need to do, and what on earth is a MET?

Secondly, what are the concerns around low-dose amitriptyline use for IBS from patients and GPs? How can we aid the discussion?

Finally, can SLGT2 inhibitors improve liver disease? Is this the new treatment for our patients with MASLD (the condition formerly known as NAFLD?

References

NEJM Exercise and CRC

METs Wikipedia

BJGP IBS & amitriptyline prescribing

BMJ SGLT2i & MASLD

NB Blog MASLD: The rebrand you never heard of

www.nbmedical.com/podcast