Miriam Hernandez Morales: Magnetogenetic Technology Development and Applications in Brain Research
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Miriam Hernandez Morales: Magnetogenetic Technology Development and Applications in Brain Research
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This year the Nobel Prize in physiology or medicine was awarded to three scientists for optogenetics – a method for activating or inhibiting neurons with light. In this episode I talk with UC Berkeley scientist Miriam Morales about magnetogenetic technologies being developed to enable activation or inhibition of specific neurons in the brain with magnetic fields as a means of understanding how the brain works and restoring normal function in individuals with neurological disorders. Her research focuses on understanding how neuronal activity causally contributes to behavior. To address this question, she has developed approaches to remotely activate ion channels and control cellular activity. Her goal is to determine how the coordinated activity of neurons and glial cells shapes brain function.
LINKS
Hernandez Morales webpage:
https://miriamhmorales.com/
Magnetogenetics review article:
https://www-jneurosci-org.proxy1.library.jhu.edu/content/46/31/e0315252026
Original research articles
https://pmc.ncbi.nlm.nih.gov/articles/PMC8479696/pdf/main.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC7204511/pdf/nihms-1574792.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC13174281/