Dementia is something many of us worry about as we get older — but what does the science actually say about risk, prevention, and brain health?
In this episode, I’m joined by neuroscientist and science communicator Dr Sarah McKay to explore what’s really happening in the brain across midlife, and how we can think about reducing dementia risk in a realistic, evidence-based way.
We talk about what dementia actually is, how it differs from normal memory changes, and why it’s not an inevitable part of ageing.
Importantly, we unpack the concept of modifiable risk factors — including hearing loss, high LDL cholesterol, depression, and traumatic brain injury — and how these factors can influence brain health over time.
We also explore brain changes during perimenopause and menopause, and address common myths and misinformation circulating online — particularly around hormones and dementia risk.
This is a thoughtful, practical conversation focused on what’s within our control — without the fear-based messaging.
BIO
Dr. Sarah McKay is a neuroscientist and science communicator, adept at making brain science accessible for enhancing health, wellbeing and performance.
An Oxford University graduate, Sarah earned her MSc and PhD in neuroscience before moving to Australia, where she conducted postdoctoral research on spinal cord injury for five years. She then founded Think Brain, a science communications and education company devoted to applied neuroscience and brain health.
She is the author of three books on brain health. The Women's Brain Book: The Neuroscience of Health, Hormones, and Happiness was published in 2018, with a second edition published in mid-2025. Baby Brain: The Surprising Neuroscience of How Pregnancy and Motherhood Sculpt Our Brains and Change Our Minds (for the Better) explores the transformative effects of pregnancy and motherhood. Her third book on brain health, written for the iconic For Dummies brand, was released in early 2025.
Links:
Dr Sarah McKay
https://drsarahmckay.com/
https://www.instagram.com/drsarahmckay/
Lancet Commission - Risk Factors for Dementia
https://www.thelancet.com/infographics-do/dementia-risk
Consensus AI
https://consensus.app/
https://mindyourbeing.com.au/
https://www.instagram.com/mindyourbeingpodcast/
https://www.facebook.com/profile.php?id=61574785410170#
https://x.com/mind_yourbeing
https://www.youtube.com/@MindYourBeingPodcast
Thanks so much for listening,
Cass x
Disclaimer:
The information provided on the Mind Your Being Podcast is for general informational, educational, and entertainment purposes only. The content shared on this podcast is not a substitute for professional medical, psychological, or nutritional advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical or mental health condition.
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