『Midlife Mayhem』のカバーアート

Midlife Mayhem

Midlife Mayhem

著者： joanne lee cornish
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 Welcome to Midlife Mayhem, where we embark on an empowering journey through the world of midlife body composition transformation. In this space, we challenge the misconceptions surrounding aging and redefine what’s possible for those navigating the exhilarating terrain of midlife and beyond. Join me as we explore the science, mindset shifts, and practical strategies that can help you sculpt the body of your dreams, proving that age is no barrier to achieving peak vitality and confidence. Whether you’re seeking to shed excess weight, gain lean muscle, or simply feel more vibrant, this podcast is your trusted companion in the pursuit of a healthier, stronger, and more resilient you. Welcome to a new era of limitless possibilities in midlife body transformation. ”Hi I’m Joanne, and I have been coaching body composition for over 30 years. I’ve worked with household names that you know, and I have worked with thousands of people in my group coaching programs. I was a pro bodybuilder in the 90’s with a top 10 physique in the world, but I only knew how to be in shape and out of shape. That frustration led me on a fascinating path of self-study where I found all the answers I could have asked for and more. But I had to dig for the answers, and I have my own ideas on why those answers are not mainstream and why the weight loss industry fails you, but I will save that for a Midlife Mayhem episode. Author of ”When Calories & Cardio Don’t Cut It”New podcast weblogCopyright 2023 All rights reserved. エクササイズ・フィットネス フィットネス・食生活・栄養 個人的成功 自己啓発 衛生・健康的な生活
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  • DHM + L-Cysteine & Alpha GPC + DLPA: Reduce Alcohol’s Effects and Unlock Laser Focus

    DHM + L-Cysteine & Alpha GPC + DLPA: Reduce Alcohol’s Effects and Unlock Laser Focus
    2025/09/10
    Welcome to Midlife Mayhem! For the first time, I’m not just talking to you through your headphones — I’m also filming this for YouTube. So if you’d rather see me chatting through today’s episode, head over to (joanne lee cornish) my YouTube channel. Today, I want to share some of the lesser-known supplement pairings I personally use and keep on hand. These aren’t your typical multivitamins or fish oils — they’re unique stacks that I pull out a couple of times a month when I need them. And since my Mastering Midlife Program kicks off on September 21, I thought this was the perfect time to give you a preview. 🍶 DHM + L-Cysteine: My “Alcohol Insurance” Stack Okay, let’s talk about what I jokingly call my going-out stack. If I know I’m going to enjoy a glass of wine or two, this is what I reach for: DHM (Dihydromyricetin): When you drink alcohol, your liver breaks it down in steps. First, ethanol (the alcohol in your drink) is broken down into acetaldehyde — and that’s the nasty stuff that makes you feel headachy, nauseous, and sluggish. Your body has an enzyme called acetaldehyde dehydrogenase, which converts that toxic acetaldehyde into harmless acetic acid (basically vinegar). The catch? Your liver can only work at a steady pace — it doesn’t speed up just because you had three margaritas. Research shows DHM can help upregulate acetaldehyde dehydrogenase, essentially nudging your body to clear out that toxic middle step faster. L-Cysteine: This one is an amino acid that helps your body make glutathione, your master antioxidant. Think of glutathione as your liver’s cleanup crew — it sweeps away leftover toxins and free radicals so you can recover more quickly. By taking L-Cysteine with DHM, you’re not only speeding up the breakdown of alcohol but also giving your body extra tools to handle the oxidative stress that comes with drinking. 💡 How I use it: If I know I’ll have more than one drink, I take one capsule of DHM (around 350–500 mg) and one capsule of L-Cysteine (500 mg) after my first drink. Honestly, if I only have one glass, I don’t need them, but I’ll often still take them — it just helps me feel clearer and better the next day. And here’s the kicker: these are simple, inexpensive supplements. The DHM I use is by Nutricost, and the L-Cysteine is by NOW — but you don’t have to stick to those brands. They’re basic compounds, no need to overpay for a fancy “hangover pill” when you can pair them yourself for less than $30 and get way more doses. ⚡️ Alpha GPC + DLPA: The Focus & Flow Stack Now, let’s shift gears to another duo I love — not for social nights out, but for when I need serious focus and mental clarity. This is my deep work stack, perfect for writing, planning, or any project that requires a lot of brainpower. DLPA (DL-Phenylalanine): This supplement is a blend of two mirror-image forms of the amino acid phenylalanine. The L-form is a precursor to dopamine — the neurotransmitter responsible for motivation, focus, and drive. Think of dopamine as the spark that helps you get things done. The D-form works differently: it helps slow the breakdown of endorphins, those natural “feel-good” chemicals your body releases when you laugh, exercise, or enjoy a great meal. By keeping your endorphins around longer, it helps sustain a positive, motivated state. Alpha GPC (L-alpha-glycerylphosphorylcholine): This is a highly bioavailable source of choline, which your brain uses to make acetylcholine — a neurotransmitter tied to learning, memory, and focus. Think of it as premium fuel for your brain’s communication system. When acetylcholine is abundant, neurons fire more efficiently, and everything feels clearer and sharper. 💡 How I use it: I don’t take these every day. For me, it’s more of a “power button” stack. If I know I need a solid 2–3 hours of uninterrupted writing, content creation, or really intense focus, I’ll take one DLPA and one Alpha GPC together. About 20–30 minutes later, it feels like the fog lifts, I’ve got more drive, and I can really lock in. Are they stimulants? Not in the jittery, wired way that coffee or pre-workouts can be. You don’t get the crash. Instead, it’s like your brain is clicking into gear — smooth energy, clearer thinking, better recall. 🧘 Mastering Midlife Program — Starts September 21! If all of this has your brain buzzing and you want to learn more about how to use supplements (without the confusion or hype), then I’d love to invite you to join me in the Mastering Midlife Program, starting September 21st. Here’s what you’ll get: 🔟 Live coaching calls over 6 weeks — each one covering a key pillar of thriving in midlife. 📚 A growing library of 70+ pieces of content — with strategies, deep dives, and explanations you can access for a full year. 🎯 My top 5 everyday supplements that I recommend for everyone, plus specialized ...
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    33 分
  • Cellular Energy, NAD+, and Gut Diversity Demystified

    Cellular Energy, NAD+, and Gut Diversity Demystified
    2025/09/08
    Recorded: September 6 (rainy morning in Idaho 🌧️) Host: Joanne Lee Cornish Theme: Cutting through the “too simple” and the “too complex” to the useful middle—so you actually know what to do and why it works. Why this episode matters There’s a giant gap in health education: on one side, fluffy tips (“eat healthy fats!”); on the other, firehose-science that sounds impressive but leaves you asking, …now what? This episode lives in the middle. You’ll get plain-English explanations of high-value concepts and, more importantly, how to implement them for midlife results. ⚡️ Heads up: Enrollment for Mastering Midlife starts really soon. It’s a 10-Step to Success program with live coaching plus a full content library so you can learn at your own pace. Details below. Episode Highlights 1) The “Gap” I Fill (00:29–03:31) The internet swings between oversimplified advice and overcomplicated biohacking. Most people don’t need more noise—they need actionable explanations and a clear progression. That’s why my programs are designed as a journey—not 10 random Zooms. 2) Why a Progressive Framework Works (03:01–04:46) Mastering Midlife follows a 10-step sequence across bloodwork, smart nutrition, supplements, exercise, and strength training. Each step builds on the last so you can understand, apply, and sustain. 3) Buzzwords You Hear Everywhere—Decoded (04:46–10:07) We name the elephant in the room: terms are tossed around like everyone learned this in school (we didn’t). This series clarifies the why and the how so you can use the info. Topics called out: mitochondria, cellular energy, NAD+, autophagy, mTOR/AMPK, BDNF, leptin resistance, metabolic flexibility, glycation, inflamaging, photobiomodulation, peptides (BPC-157, tesamorelin, GHK), exosomes, stem cells, senescent cells, HRV, cold exposure/brown fat, methylation, zonulin, LPS, histamine intolerance, oxalates, collagen cross-linking, microdosing, sarcopenia, longevity genes, and more. 4) Deep Dives (Plain English) A) Mitochondria & Cellular Energy (10:07–18:43) Mitochondria are more than “little batteries.” They decide: How efficiently you burn fat How much energy is available to brain/muscle/organs How quickly you age Cellular energy = ability to produce ATP (the “currency of life”). Low ATP → fatigue, cravings, slow recovery, poor gains. Support via quality food, smart meal timing (including some fasting), resistance training, sleep, and light (e.g., red light therapy). B) NAD+ & Why Everyone’s Talking About It (18:43–23:54) NAD+ is a coenzyme required to turn food into usable energy. Levels decline with age. You’ll hear about NR/NMN (precursors). Lifestyle also protects NAD (exercise, sleep, fasting). 5-Amino-1MQ (which I carry) supports your own NAD production. Warning: medications may create great scale changes, but cellular health still matters—don’t abandon the basics. C) Microbiome Diversity (24:19–29:49) Think of your gut like a rainforest—diversity = resilience. Diverse microbes = better digestion, vitamins, hormone balance, immune regulation, even mood/cognition (gut-brain axis). Midlife naturally reduces diversity. Counter it by: Eliminating ultra-processed foods (non-negotiable) Eating more fiber (feeds good bacteria) Including fermented foods (adds good bacteria) D) LPS & Leaky Gut—The Silent Saboteur (29:49–34:35) LPS (lipopolysaccharide) lives on certain gut bacteria. Fine inside the gut; toxic if it leaks out. With leaky gut, LPS escapes → big immune reaction → systemic inflammation, brain fog, joint pain, fatigue, insulin resistance, mood issues; linked with autoimmunity. Drivers: ultra-processed food, irritants, toxins, antibiotics, high sugar. I have a free leaky gut video—email me. E) Oxidative Stress (34:57–41:51) When cells make energy, free radicals (sparks) are created. Antioxidants are the cleanup crew. If sparks build up without cleanup, you get a fire = oxidative stress. Result: faster aging (wrinkles), joint issues, chronic disease risk, low energy. Fix the inputs: whole foods, consistent activity, sleep, stress management. As we age, internal antioxidant systems decline → diet quality matters more. 5) Big Picture (42:18–44:57) Weight alone isn’t the game. Cellular health is. When people understand the why, simple solutions are finally implemented—and they stick. 6) The Power of Community (45:20–46:34) Join as a front-row participant or low-key spectator; the group dynamic accelerates results. Coaching is not about dumping information—it’s progression + conversation. About the Program: Mastering Midlife — 10-Step to Success Starts soon (runs live once per year). 10 progressive steps that cover: bloodwork, smart nutrition, supplementation, strength training, recovery, metabolic health, gut health, and more. Live coaching calls + full content library (review at your pace all year)....
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    51 分
  • The Dangerous Advice That’s Keeping Midlifers Weak

    The Dangerous Advice That’s Keeping Midlifers Weak
    2025/08/29
    Show Notes – Midlife Mayhem Podcast Episode Type: Venting / Educational Rant Program Mentioned: Mastering Midlife (Sept 21 – Nov 1) → www.midlifemonth.com 🎙️ Episode Overview In this episode, Joanne takes aim at a recent Telegraph article that claimed you can lose weight without losing muscle by following outdated and misleading advice. From the laughably low protein recommendations (45g/day for women) to the suggestion that light weights and bodyweight exercise are enough for midlife muscle preservation, Jo breaks down why this kind of misinformation is dangerous—not just frustrating. This episode is raw, fiery, and unapologetic—a venting session that highlights why midlife is not the time for “everyone gets a trophy” advice. Instead, it’s the time for clear, science-backed strategies that actually protect muscle, metabolism, and long-term vitality. 🔥 Key Topics Covered 1. Why 45g of Protein is a Joke The article recommended ~0.75 g/kg of protein per day (≈45g for women, 55g for men). Joanne explains why this 1960s RDA guideline is dangerously outdated and fails to account for modern research, especially in midlife when anabolic resistance sets in. For true muscle preservation, most adults need closer to 1.6–2.2 g/kg bodyweight. That’s triple what the article suggested. 2. Anabolic Resistance: The Silent Muscle Killer Jo breaks down the science of anabolic resistance and its connection to insulin resistance: Insulin resistance → harder to move glucose into muscle. Anabolic resistance → harder to move amino acids into muscle. Result: even if you think you’re eating enough protein, your muscles may not be getting fed. Why this matters: muscle loss accelerates with age, even for people who “do all the right things,” unless nutrition and training are dialed in. 3. The “Light Weights & Pilates” Trap The article claimed bodyweight training, yoga, Pilates, and light weights with high reps are “enough” for muscle preservation in midlife. Joanne explains why this is not effective for building or maintaining meaningful lean mass. Strength training needs progressive overload—challenging resistance that forces muscles to adapt. While bodyweight and Pilates have benefits, they don’t replace structured resistance training for midlife muscle protection. 4. Why This Matters Beyond Vanity Holding onto muscle isn’t about just looking “toned”—it’s about survival and independence later in life. Without enough muscle: Metabolism plummets. Fatigue and frailty increase. Quality of life in your 70s and 80s diminishes sharply. Midlife is the one opportunity to re-route the trajectory of aging—miss it, and the next chapter becomes exponentially harder. 5. The Problem With Mainstream Advice Articles like this reinforce mediocrity disguised as inclusivity: “everyone’s a winner” messaging. Jo argues this robs people of their chance to succeed because they’re never told the truth about what’s necessary. Clear, accurate information empowers people to do the work—and it doesn’t need to be complicated. It just needs to be correct. 6. Midlife as the Opportunity Window Too many people fear midlife without realizing the real fear should be what comes after if they don’t act now. Midlife = chance to reset metabolism, protect muscle, preserve energy, and ensure the later decades of life are vibrant. Ignore it, and the outcome is predictable: loss of muscle, independence, and quality of life. 💡 Cutting-Edge Add-Ons Protein Distribution Matters → It’s not just how much protein you eat, but how you spread it through the day (aim for 25–40g per meal with sufficient leucine). The Role of Resistance Training → Strength training triggers mTOR and muscle protein synthesis. Lighter loads can work only if trained to failure—but that’s rarely sustainable. Metabolic Flexibility → Without muscle, the body loses its best tool for glucose disposal and fat utilization, fueling insulin resistance. Hormonal Influence → Midlife shifts in estrogen, progesterone, and testosterone amplify anabolic resistance—making accurate protein and strength training strategies non-negotiable. 📢 Featured Program: Mastering Midlife Midlife doesn’t have to mean decline. Joanne’s signature Mastering Midlife program runs Sept 21 – Nov 1 and gives you the full roadmap for building muscle, balancing hormones, optimizing metabolism, and rewriting the script for your next decades. 👉 Learn more and join at www.midlifemonth.com 🧭 Listener Question Joanne ends this rant with a question for her audience: Should she create a dedicated program for people using weight loss medications (GLP-1s, etc.)—a short 3–4 hour video course called RX Success—to fill the massive coaching gap that doctors aren’t covering? Email Jo your thoughts at jo@theshrinkshop.com. ✅ Bottom line: Don’t buy into outdated “light weights and 45g ...
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    20 分
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