What makes some stroke cases more severe than others, and what can be done to improve outcomes? In this episode of Medspeak by the Chinese Medical Journal, Dr. Wu Simiao and Dr. Craig S. Anderson discuss their recent study on severe acute ischemic stroke.

Drawing on data from over 4,000 patients in China, they explore why some people with stroke decline quickly, which treatments show the most promise, and how hospitals can better support recovery in patients at high-risk.

This podcast, based on the study titled “Clinical course, causes of worsening, and outcomes of severe ischemic stroke: A prospective multicenter cohort study,” aims to delve into deep discussions regarding the underexplored domain of stroke, to improve the quality of life.

Host: John L

Guests: Dr. Wu Simiao and Dr. Craig S. Anderson

Summary:

In this podcast, we explore the progression of severe ischemic stroke, the impact of key risk factors, and how therapies like endovascular treatment and intravenous thrombolysis affect patient outcomes.

Will the humanized monoclonal antibody CM310 transform treatment outcomes for patients with atopic dermatitis?

In this episode, we speak with Dr. Jianzhong Zhang, Professor at Peking University People’s Hospital, who introduces a breakthrough drug for atopic dermatitis called CM310 and discusses its potential to improve the quality of life for patients living with this chronic skin condition.

In 2024, Dr. Zhang and his collaborators published the results of a pivotal clinical trial evaluating the efficacy and safety of CM310. The article is titled, “Efficacy and safety of CM310 in moderate-to-severe atopic dermatitis: A multicenter, randomized, double-blind, placebo-controlled phase 2b trial.”

Guest: Dr. Jianzhong Zhang
Host: John L

Summary:

We explore the potential of a monoclonal antibody drug—named CM310—for treating atopic dermatitis, focusing on the results of a clinical trial conducted in China and published in the Chinese Medical Journal.

Can cardiovascular health (CVH) assessment based on Life’s Essential 8 framework help prevent non-communicable diseases?

In this episode, we speak with Dr. Ningjian Wang, Professor at the School of Medicine, Shanghai Jiao Tong University, who explains the American Heart Association’s cardiovascular health framework called ‘Life’s Essential 8’ and its association with the risk of non-communicable chronic diseases (NCDs).

The potential role of Life’s Essential 8 in preventing NCDs and promoting cardiovascular health is the focus of an article by Dr. Wang and collaborators published in Chinese Medical Journal. The article is titled, “Life's Essential 8 and risk of non-communicable chronic diseases: Outcome-wide analyses.”

Guest: Dr. Ningjian Wang
Host: John L

Summary:

We explore the link between cardiovascular health assessed using the Life’s Essential 8 framework and the risk of non-communicable diseases, based on evidence from a study published in Chinese Medical Journal