Arthritis affects millions of people, but the underlying causes are still not fully understood. What makes the immune system that normally protects us suddenly attack our joints? And why do arthritis flares seem to arrive without warning?

In this episode, we explore how certain immune cells or signals might be responsible for switching inflammation on.

We hear from Garvan's Dr Etienne Masle-Farquhar, who is mapping these processes in both rheumatoid arthritis and osteoarthritis, with the goal of predicting flares earlier and guiding more effective treatment.

Support Garvan research: https://www.garvan.org.au/support-us/give-now

See omnystudio.com/listener for privacy information.

For decades, the fight against cancer has focused on killing the tumour cell. We treated cancer like an isolated entity that needed to be destroyed – but what if we’ve been looking at the wrong target?

In this episode, we delve into the critical insight that cancer is not just a rogue cell – it’s an entire ecosystem – and that ecosystem is the key to unlocking a new class of cures.

We hear from Garvan's Dr Ankur Sharma, who is using precision technology to dissect how the environment around liver cancers allows them to grow unchecked. The ultimate goal for this research is to develop better diagnostics and treatments for this deadly cancer.

Support Garvan research: https://www.garvan.org.au/support-us/give-now

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Therapies and drugs have evolved enormously in the last 30 years. For example, in cancer, where previously our options were limited to surgery, chemotherapy and radiotherapy, we’re now hearing terms like cancer immunotherapy, targeted therapies and even cancer vaccines. Many of these are biologics.

In this episode you’ll hear from Dr Rachel Galimidi who is at the forefront of biologics drug development and is working to make new and better treatments for a range of diseases.

Support Garvan research: https://www.garvan.org.au/support-us/give-now

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Pancreatic cancer is one of the toughest cancers to treat – it’s aggressive, often diagnosed late, and doesn’t respond well to standard therapies. In this episode, we meet Professor Marina Pajic who is working at the cutting-edge of science to transform how we understand and treat this disease.

Support Garvan research: https://www.garvan.org.au/support-us/give-now

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Garvan is one of Australia's largest independent medical research institutes with a single focus: to make discoveries that will improve health for all. In this episode, you’ll hear from Executive Director Professor Benjamin Kile on how he came to be at Garvan's helm and his strategy for driving extraordinary science that will have transformational impact for patient lives.

Support Garvan research: https://www.garvan.org.au/support-us/give-now

See omnystudio.com/listener for privacy information.

Support Garvan research: https://www.garvan.org.au/support-us/give-now

See omnystudio.com/listener for privacy information.

In Australia alone, 50 people are diagnosed with Parkinson's every day. Therapy options are limited, as they are for other movement and muscle disorders, such as ataxia and dystonia. In this episode of Medical Minds, we meet neurologist and researcher Associate Professor Kishore Kumar, who is working on the next big breakthroughs for treatment.

Support Garvan research: https://www.garvan.org.au/support-us/give-now

See omnystudio.com/listener for privacy information.

Support Garvan research: https://www.garvan.org.au/support-us/give-now

See omnystudio.com/listener for privacy information.