In the life sciences, an astounding amount of unused products and materials end up in landfills instead of contributing to research progress. This issue arises across the product lifecycle, from liquidated biotech start-ups that abandon equipment to over-purchasing and pipeline deprioritization at successful firms. Even well-intentioned suppliers encounter forecasting challenges that leave perfectly good items discarded!

In this episode of Listen In, explore the root causes of waste in our industry, as we draw on real-world examples of failed companies, discontinued pipelines, and canceled orders. We will examine the ripple effects this has on both operational efficiency and the broader sustainability goals of life science organizations.

We will also introduce Wasteless Bio, a dedicated marketplace designed to keep high-quality, unused products in circulation—helping researchers access discounted reagents and instruments while reducing environmental impact.

Whether you are a biotech executive, lab manager, or supplier, you will gain a clearer understanding of how to rescue valuable resources from the trash and reinvest them back into scientific innovation.

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Automated counting of certain cell types is notoriously challenging due to their irregular shapes, variable nuclei number, autofluorescence, and often high amounts of debris in samples.

However, with the latest developments in cell-counting hardware and app technology, automated counting of even challenging cells is simpler than ever.

In this episode, see how you can achieve reliable automated cell counts with the CellDrop Automated Cell Counter.

Using hepatocytes as an example, you will learn how the machine learning technology integrated into DeNovix’s Hepatocyte app can save time, reduce human error, and provide consistent results.

Watch the full presentation here: https://events.bitesizebio.com/automated-hepatocyte-counting-new

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

In this episode of Listen In, we showcase cutting-edge mass spectrometric analysis of mucins, including the characterization of mucinases, enrichment techniques, and complete mucinomic mapping of translationally relevant mucin proteins.

Mucins are a diverse family of high molecular weight glycoproteins that play critical roles in protecting and lubricating epithelial surfaces, making them integral to numerous physiological processes and disease states.

As a promising class of biomarkers, mucins may offer unique insights into various pathologies, such as cancer and chronic inflammatory diseases. However, their complex structures and extensive glycosylation present significant challenges in their study and application.

Mucin-domain glycoproteins are densely O-glycosylated and play key roles in many biological functions.

However, their dense O-glycosylation remains enigmatic both in the glycoproteomic landscape and structural dynamics, primarily due to the challenges associated with studying mucin domains.

In this episode, you will get an introduction to the (glyco)proteomic techniques used in Mucinomics and learn how proper sample preparation of mucin-containing tissues for mass spectrometry is key to discovery.

MilliporeSigma is the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany.

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In this episode, learn about latest advancements in multiplex assay technology.

Hear from real user experience how the advanced xMAP INTELLIFLEX® DR-SE Instrument revolutionizes assay multiplexing, enabling simultaneous rapid data acquisition for multiple sample parameters to expand the depth and breadth of your research.

Watch the full presentation here: https://events.bitesizebio.com/user-experience-of-the-xmap

This compact, flow-based multiplex platform integrates xMAP® Technology with modern enhancements to streamline assay development, enhance user experience, and deliver fast, reliable results by acquiring data for two parameters per analyte simultaneously.

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

Immunoassays are pivotal in scientific research, enabling the precise identification and measurement of specific analytes. They pave the way for investigations into disease mechanisms, discovering biomarkers, and evaluating the efficacy of potential therapeutic interventions.

The key reagents included in an immunoassay can significantly impact reliability and reproducibility, underscoring the importance of understanding critical components within immunoassay kits.

When selecting an immunoassay platform, it's essential to consider critical elements such as multiplexing capabilities and sensitivity needs as part of the experimental design.

Additionally, understanding the various assay formats and their data outputs can aid in the immunoassay selection process.

In this episode, immunoassay experts give practical guidance in these areas, empowering researchers to achieve more precise and meaningful results, thereby advancing knowledge and understanding in various scientific fields.

MilliporeSigma is the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany.

For Research Use Only. Not For Use In Diagnostic Procedures.

Watch the full presentation here: https://events.bitesizebio.com/inside-immunoassays-strategies-to

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Multicolor 3D fluorescent confocal microscopy presents significant challenges in image acquisition and data analysis. However, AI is making a massive impact on 3D spatial biology.

This episode of Listen In explores the incorporation of AIVIA, an AI-powered image analysis software, into workflows to address these challenges in analyzing multicolor fluorescent microscopy data of 3D organoids.

See how AIVIA’s tools enhance the visualization and quantification of cellular structures and organoids, enabling precise segmentation and analysis of fluorescent signals.

And get a showcase of how AIVIA supports Python-based image analysis for microscopists.

Watch the full presentation here: https://events.bitesizebio.com/ai-powered-3d-organoid-analysis

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

In this episode of Listen In, explore high-throughput and wide-range protein concentration analysis that can deliver a 20-fold improvement in time and budget savings.

Protein concentration is an obligatory critical quality attribute necessary to determine total protein content in biopharmaceutical formulations.

Concentration determination is necessary before many downstream assays. A UV-based spectrophotometric assay using the protein’s extinction coefficient is the most typical method.

Conventional UV methods or a specialized approach using variable pathlength slope spectroscopy could take one day to measure 15 samples in triplicate.

Larger batches would require multiple analysts for a single-day turnaround time.

With vast studies spanning multiple projects, protein concentration analysis becomes a key deliverable before all other methods can be performed. Thus, efficient rapid concentration analysis with a minimal volume requirement is essential.

Hit play to learn how the Lunatic (Unchained Labs, Pleasanton, CA) offers rapid, plate-based concentration measurement with minimal prep and sample volume requirements.

It utilizes only two microliters per sample, can analyze 96 wells in less than 12 minutes, and provides accurate measurements over a broad concentration range, from 0.03 mg/mL to 176 mg/mL.

Watch the full presentation here: https://events.bitesizebio.com/high-throughput-and-wide-range/join

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Learn more about the capabilities of MULTI-seq in single-cell sequencing in this episode of Listen In. Developed by the Gartner Lab at UCSF, this innovative multiplexing method increases sample and cell throughput while minimizing cost and improving your data quality.

From modest experiments to expansive 96-plex studies and beyond, MULTI-seq enables truly mechanistic studies. Hit play to explore the potential of this tool and how it could benefit your research.

Watch the full presentation here: https://events.bitesizebio.com/multiplexing-magic-how-multi-seq/join

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/