Rewriting the Risk Equation: The Expanding Role of Lp(a) in Atherosclerotic Disease

Hosted by Dr. Underberg, the Rewriting the Risk Equation: The Expanding Role of Lp(a) in Atherosclerotic Disease podcast is designed to equip clinicians with the latest evidence on Lp(a) biology, screening strategies, and current and emerging therapeutic options. Along with Drs. Soffer, Kulkarni and Wilkinson, they will explore the integration of Lp(a) assessment into routine practice, implications for high-risk populations including those with familial hypercholesterolemia (FH), and strategies to mitigate cardiovascular risk until targeted therapies become available.

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Can genetic scores unlock better outcomes for patients with FH? This special Snippet from our Lipid Insights podcast series dives into the award-winning abstract from #NLASessions 2025, exploring how polygenic risk scores for coronary artery disease may transform ASCVD prediction and management. Tune in and see what’s next in lipid science.

Guest Host
Daniel E. Soffer, MD, MNLA
University of Pennsylvania Health System
Internal Medicine/Clinical Lipidology
Perelman Center for Advanced Medicine
Philadelphia, PA

Guest
Alexis Baass, MD, MSc, FNLA Alexis Baass, MD, MSc, FNLA
Director of the Lipids
Nutrition and Cardiovascular Prevention Clinic
Montreal Clinical Research Institute
Montreal, QC, Canada

Click here to see the video version of this episode

In this episode of Lipid Insights, Dr. Peter Jones and guest Dr. Kevin Maki explore whether beef deserves its long-standing reputation as a driver of cardiovascular disease. Drawing on a recent systematic review and meta-analysis, they examine beef’s impact on cholesterol, blood pressure, and other key CVD risk factors—providing fresh perspective for clinicians navigating dietary guidance.

This podcast has been approved for AMA PRA Category 1 Credit™. This activity is eligible for ACPE, ANCC, and CDR credit. To read full accreditation information and claim credit, CLICK HERE.

In this short episode, guest host Dr. Dan Soffer chats with Dr. Joshua Hyman, the Young Investigator Award winner at #NLASessions 2025. Dr. Hyman gives a quick overview of his award-winning abstract and shares insights from his work in advancing lipid research.

Hosted by Dr. Dan Soffer, this conversation brings NLA President Dr. Willard and Beth Jackson together to unpack the Association’s guidance, “LDL Cholesterol Management Simplified in Adults – Lower for Longer is Better.” The trio turns a big message into practical moves: why lifetime LDL exposure matters, who needs more aggressive targets, and how to streamline therapy choices from high-intensity statins to add-ons (ezetimibe, PCSK9-directed options) when goals aren’t met. They share real-world tactics on adherence, stepwise intensification, shared decision-making, and navigating special populations—all in a clear, clinic-ready format.

Read the featured article HERE

Watch this video on YouTube HERE

Guest Host
Daniel E. Soffer, MD, MNLA
University of Pennsylvania Health System
Internal Medicine/Clinical Lipidology
Perelman Center for Advanced Medicine
Philadelphia, PA

Kaye-Eileen Willard, MD, FNLA
Medical Director Lipid Clinic
Physician Advisor, Ascension SE Wisconsin
Chief of Staff Ascension All Saints
Chair Joint Chiefs of Staff Ascension SE Wisconsin
Racine, WI

Beth Jackson, MSN, ACNS-BC, CLS, FNLA
Prevention Lipid Clinic
App Manager
Baylor Scott and White
Division of Cardiology
Temple, TX

In this episode, Alan Brown, MD, MHA, MNLA sits down with Rebecca Juliano, PhD, MPhil, MA to discuss a first-in-human study of an investigational ANGPTL4 inhibitory antibody. The conversation explores how this novel therapeutic approach safely and effectively reduces plasma triglycerides and remnant cholesterol—key drivers of residual cardiovascular risk. Listeners will gain insight into the mechanism of action, clinical significance, and potential role of ANGPTL4 inhibition in the evolving landscape of lipid management.

View this Episode on YouTube HERE

Guests

Rebecca Juliano, PhD, MPhil, MA

Chief Development Officer

Marea Therapeutics

San Francisco, CA

Explore the NLA’s new guidance on building effective, team-based approaches to improve outcomes in clinical lipidology and cardiometabolic care.

Read the Expert Clinical Review HERE

View this Episode on YouTube HERE

Guest Host

Daniel E. Soffer, MD, MNLA

University of Pennsylvania Health System

Internal Medicine/Clinical Lipidology

Perelman Center for Advanced Medicine

Philadelphia, PA

Guests

Mary Katherine Cheeley, PharmD, CLS, FNLA

Executive Director, Ambulatory Pharmacy Services

Grady Health System

Atlanta, GA

Michael Wilkinson, MD, FNLA

Associate Professor

Division of Cardiovascular Medicine

UC San Diego

San Diego, CA

Dive into the complexities of Persistent Chylomicronemia with this special episode recorded live at the recent National Lipid Association Scientific Sessions. Guest host Christie Ballantyne, MD, is joined by leading experts Seyedmohammad Saadatagah, MD, Erin Michos, MD, and Daniel Gaudet, MD, PhD, to break down key takeaways from the newly released Joint Expert Clinical Consensus from the National Lipid Association and the American Society for Preventive Cardiology: Recognition and Management of Persistent Chylomicronemia. This engaging discussion explores diagnostic challenges, treatment strategies, and why recognizing this condition is critical to preventing severe complications like pancreatitis. Don’t miss this deep dive into one of the most misunderstood lipid disorders.

The video episode is available on YouTube: https://youtu.be/7jbMin8Lk3s