Cesarean delivery on maternal request requires individualized counseling. Reduced risks of pelvic floor disorders should be weighed against surgical risks and future risks including abnormal placentation. Author Marianna Alperin, MD, MS, from UC San Diego School of Medicine, discusses this and more with JAMA Deputy Editor Linda Brubaker, MD.

Related Content:

• Cesarean Delivery on Maternal Request
• Cesarean Delivery—Reply
• Cesarean Delivery

The GLP-1 receptor agonists reduce appetite and greatly facilitate weight loss. Robert Kushner, MD, of Northwestern University Feinberg School of Medicine joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss appropriate diet and exercise recommendations for patients receiving GLP-1 receptor agonists for weight loss.

Related Content:

• Lifestyle Modification and Incretin-Based Therapy for Obesity
• The Conundrum of Exercise for Weight Management in the GLP-1 Receptor Agonist Era

Amyotrophic lateral sclerosis (ALS), which affects about 25 000 individuals in the US, causes progressive weakness but has varied presentations. Several FDA-approved medications are now available for ALS. Author John Ravits, MD, of UC San Diego School of Medicine joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss current evidence regarding diagnosis and treatment of ALS.

Related Content:

• Amyotrophic Lateral Sclerosis
• Pridopidine in Amyotrophic Lateral Sclerosis
• What Is Amyotrophic Lateral Sclerosis?
• CNM-Au8 in Amyotrophic Lateral Sclerosis
• Safety and Efficacy of PrimeC in Amyotrophic Lateral Sclerosis
• Traumatic Brain Injury and Risk of Amyotrophic Lateral Sclerosis