『Irish Thoracic Society Podcast Productions』のカバーアート

Irish Thoracic Society Podcast Productions

Irish Thoracic Society Podcast Productions

著者： The Podcast Studios
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 Breath work A Respiratory Medicine podcast for busy respiratory nerds who want to keep up-to-date with the constantly evolving world of the lung. Every month we speak with respiratory experts on their areas of special interest. Our goal is to provide YOU with interactive and easy to listen to clinical updates. We will cover presentation, clinical reasoning, diagnostics and treatments but also new and exciting changes coming down the line. Delivered at a time convenient to you in 20-30 minute episodes. Inspire Meet your Respiratory Medicine heroes and hear how they got to where they are today. There are now more people than ever working in the respiratory medicine sphere. In this podcast we speak to Physicians, scientists, nurses, physiologists and more. We learn about their career paths to date, how they have achieved such success and advice for others hoping to follow suit. Some of these discussions are profession specific, but much of the advice is applicable to anyone trying to progress in their career. Social Media Website: https://irishthoracicsociety.com/ X/Twitter: irishthoracicS LinkedIn: Irish Thoracic Society Instagram: Irishthoracicsociety 科学 衛生・健康的な生活 身体的病い・疾患
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  • Breathwork: Pulmonary Hypertension with Professor Sean Gaine (Part 2)

    Breathwork: Pulmonary Hypertension with Professor Sean Gaine (Part 2)
    2025/07/07
    This week, we’re joined by Professor Seán Gaine, Ireland’s foremost expert in pulmonary hypertension. In this insightful episode, he shares his expert perspective on the diagnosis, classification, and clinical presentation of the condition, as well as the latest advances in treatment. A must-listen for all healthcare professionals, Professor Gaine also discusses when to suspect pulmonary hypertension and highlights the nuances in the management of patients with pulmonary hypertension. Don’t miss this opportunity to learn from a global leader in the field. Chapters 0:52 Rapid fire round on pulmonary hypertension 01:42 Definition of pulmonary hypertension 02:08 Signs and symptoms of pulmonary hypertension 02:56 Five groups of pulmonary hypertension 03:33 Group 1 pulmonary hypertension: Pulmonary arterial hypertension 04:34 Group 2 pulmonary hypertension: Left heart disease 05:23 Group 3 pulmonary hypertension: Chronic lung disease/hypoxia 05:58 Group 4 pulmonary hypertension: Pulmonary vascular obstruction 06:30 Group 5 pulmonary hypertension: Miscellaneous 07:25 Referral to the national pulmonary hypertension centre: right heart catheterisation 09:37 Work up in the pulmonary hypertension clinic 11:06 Risk stratification in pulmonary hypertension 12:06 Diagnostic criteria pulmonary hypertension Dynamic testing right heart catheterisation: Cardiopulmonary exercise testing Reliability of right heart catheterisation Treatment algorithm in pulmonary arterial hypertension Tripple therapy for high risk patients Double combination therapy for non-high risk patients Fourth treatment pathway, Quadruple therapy?: Sotatercept - an activin scavenger Treatment options for groups 4 pulmonary hypertension: Balloon pulmonary angioplasty Treatment options for groups 2, 3 and 5 Side effects of triple therapy Lung transplant in pulmonary hypertension: Double or single lung transplant Pitfalls in the acute management of patients with pulmonary hypertension Interpretation of the B Natriuretic Peptide level Medications contraindicated pulmonary hypertensions Outcomes in pulmonary hypertension Take home message on pulmonary hypertension Show Notes - https://lumen5.com/user/edofficer/sotatercept-emergin-d5jg6/ - Irish Thoracic Society Flashcard Pulmonary Hypertension https://irishthoracicsociety.com/wp-content/uploads/2021/06/5.-Pulmonary-Hypertension.pdf - Benza RL, Kanwar MK, Raina A, et al. Development and validation of an abridged version of the REVEAL 2.0 risk score calculator, REVEAL Lite 2, for use in patients with pulmonary arterial hypertension. Chest 2021; 159: 337–346. - Humbert M, Kovacs G, Hoeper MM, Badagliacca R, Berger RMF, Brida M, et al. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. European Respiratory Journal. 2022:2200879. DOI: https://doi.org/10.1183/13993003.00879-2022 - Chin KM, Gaine SP, Gerges C, Jing Z-C, Mathai SC, Tamura Y, et al. Treatment algorithm for pulmonary arterial hypertension. European Respiratory Journal. 2024;64(4):2401325. DOI: https://doi.org/10.1183/13993003.01325-2024 - Hoeper, M.M., Badesch, D.B., Ghofrani, H.A., Gibbs, J.S.R., GombergMaitland, M., McLaughlin, V.V. et al. (2023) ‘Phase 3 trial of sotatercept for treatment of pulmonary arterial hypertension’, New England Journal of Medicine, 388(17), pp. 1478–1490. Available at: https://doi.org/10.1056/NEJMoa2213558 - Humbert M, McLaughlin VV, Badesch DB, Ghofrani HA, Gibbs JSR, Gomberg-Maitland M, et al. Sotatercept in Patients with Pulmonary Arterial Hypertension at High Risk for Death. N Engl J Med. 2025;392(20):1987-2000. DOI: 10.1056/NEJMoa2415160
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    40 分
  • Inspire: Professor Sean Gaine on setting up pulmonary hypertension centres and his role as chief medical officer for the Irish Olympic Teams (Part 1)

    Inspire: Professor Sean Gaine on setting up pulmonary hypertension centres and his role as chief medical officer for the Irish Olympic Teams (Part 1)
    2025/06/23
    This week, we speak with Professor Sean Gaine about his distinguished career—from his work establishing the Pulmonary Hypertension Program at Johns Hopkins Hospital and later founding Ireland’s National Pulmonary Hypertension Centre as well as serving as Chief Medical Officer for the Irish Olympic Teams. He shares thoughtful insights and experiences from a remarkable career with more stories than could ever be squeezed into one episode. Chapters 01:56 Residency in the Johns Hopkins Hospital 03:37 Introduction to Pulmonary Hypertension 05:56 Establishing the Pulmonary Hypertension Unit in the Johns Hopkins Hospital 14:01 Establishing the National Pulmonary Hypertension Programme in Ireland 15:51 Essential role of clinical nurse specialists 18:01 Chief Medical Officer Irish Olympic Teams 25:46 Sustaining enthusiasm in a career in medicine Show Notes 1. Rubin, Lewis J., and Stuart Rich, editors. Primary Pulmonary Hypertension. Marcel Dekker, 1996. Lung Biology in Health and Disease. 2. https://www.irishtimes.com/sport/athletics/2024/05/18/jamie-costin-was-27-in-the-shape-of-his-life-ready-for-the-olympics-then-he-got-hit-by-a-truck/ 3. https://lumen5.com/user/edofficer/sean-gaine-olympic-cq0g0/
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    29 分
  • Breathwork: Asthma Biologic Therapies with Mr. Stephen Shelly (Part 2)

    Breathwork: Asthma Biologic Therapies with Mr. Stephen Shelly (Part 2)
    2025/05/26
    Description This week we speak to Mr Stephen Shelly again about the exciting but sometimes mysterious world of asthma biologics. We speak about the different biologics, going about getting approval to start an asthma biologic, training, and treatment response. We speak about the potential impact that asthma biologics are going to have on the future of asthma (and hopefully COPD!), the cost benefit analysis and the limitations of these new wonder drugs. Chapters 0.42min Intro to Biologics 1.00min Rapid fire round 1.52min Severe asthma & biologic eligibility 3.50min Available biologics 6.50min Which biologic? 7.30min Journey to asthma biologic 13.55min Asthma biologic administration 15.30min Monitoring while on asthma biologic 16.40min Training for asthma biologic admin at home 18.50min Assessing treatment response 21:10min Patient expectations 24:50min Are inhalers still needed? 26:12min Pitfalls in treatment with asthma biologics 28:54min Cost-benefit analysis 31.30min Take-home points Show notes Dupilumab https://www.nejm.org/doi/10.1056/NEJMoa1804092 Mepolizumab https://www.nejm.org/doi/10.1056/NEJMoa1403290 Omalizumab https://www.jacionline.org/article/S0091-6749(01)65945-1/fulltext Benralizumab https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)31322-8/abstractTezepelumab https://doi.org/10.1164/rccm.202210-2005OC Difficult to treat asthma (GINA) https://ginasthma.org/wp-content/uploads/2024/11/GINA-Severe-Asthma-Guide-2024-WEB-WMS.pdf Asthma compliance programmes Ireland https://www.rcsi.com/dublin/research-and-innovation/innovation/investors-entrepreneurs-and-spin-outs/phyxiom
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    33 分

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