In this episode, Anca tells the fascinating story of AlphaFold, the AI system that cracked one of biology’s greatest mysteries: how proteins fold. What started as an ambitious challenge at DeepMind has become a transformative breakthrough with far-reaching implications for medicine, drug discovery, and beyond.

Topics Covered:

• Why protein folding matters and why it was such a hard problem

• How DeepMind shifted from game-playing AIs like AlphaGo to solving core problems in biology

• The evolution from AlphaFold 1 to AlphaFold 2 and what made the second version revolutionary

• How AlphaFold uses deep learning and transformer models to predict 3D protein structures

• The impact of AlphaFold across global research, healthcare, and biotech

• What’s next in AI-powered biology—from protein complexes to drug discovery

Credits:
Production: MedShake Studio
Host: Anca Petre

✔ Stay connected and learn more:

• LinkedIn: linkedin.com/in/ancapetre

• Website: www.ancapetre.com & www.medshake-studio.com

• Email: anca@medshakestudio.com

More about the podcast:
Every week, I dive into the most transformative trends at the intersection of technology and healthcare. From AI-driven breakthroughs in diagnostics to the role of blockchain in securing health data, from decentralized science (DeSci) to NFT-powered health innovation, and from gamified fitness to the potential of digital twins, I’m here to make complex topics simple, accessible, and exciting.

Hosted by Ausha. See ausha.co/privacy-policy for more information.

In this episode, we explore a major breakthrough in the world of artificial intelligence: Chain-of-Thought prompting. This new technique teaches AI to reason step by step—just like a human would—and it’s revolutionizing how machines tackle complex problems.

Topics Covered:

• What Chain-of-Thought prompting is and how it works

• Why traditional AI models struggled with multi-step reasoning

• How Chain-of-Thought led to massive performance gains on tasks like math word problems

• The importance of reasoning transparency and trust in AI systems

• Implications for healthcare, logic, and problem-solving across industries

• How this shift signals a deeper, more human-like kind of machine intelligence

Credits:
Production: MedShake Studio
Host: Anca Petre

✔ Stay connected and learn more:

• LinkedIn: linkedin.com/in/ancapetre

• Website: www.ancapetre.com & www.medshake-studio.com

• Email: anca@medshakestudio.com

More about the podcast:
Every week, I dive into the most transformative trends at the intersection of technology and healthcare. From AI-driven breakthroughs in diagnostics to the role of blockchain in securing health data, from decentralized science (DeSci) to NFT-powered health innovation, and from gamified fitness to the potential of digital twins, I’m here to make complex topics simple, accessible, and exciting.

Hosted by Ausha. See ausha.co/privacy-policy for more information.

In this episode, we unpack a groundbreaking study that could reshape how we think about mental health care. For the first time, a fully automated generative AI chatbot—Therabot—has been rigorously tested in a randomized controlled trial to treat depression, anxiety, and eating disorders. The results? Promising, and possibly game-changing.

Topics Covered:

• How Therabot was developed and clinically validated

• Key findings from the NEJM AI-published study

• The significance of small but meaningful improvements in mental health symptoms

• Understanding therapeutic alliance with AI: can bots build trust?

• Implications for access, scalability, and the future of digital mental health care

• Ethical considerations and what still needs to be addressed

Credits:
Production: MedShake Studio
Host: Anca Petre

✔ Stay connected and learn more:

• LinkedIn: linkedin.com/in/ancapetre

• Website: www.ancapetre.com & www.medshake-studio.com

• Email: anca@medshakestudio.com

More about the podcast:
Every week, I dive into the most transformative trends at the intersection of technology and healthcare. From AI-driven breakthroughs in diagnostics to the role of blockchain in securing health data, from decentralized science (DeSci) to NFT-powered health innovation, and from gamified fitness to the potential of digital twins, I’m here to make complex topics simple, accessible, and exciting.

Hosted by Ausha. See ausha.co/privacy-policy for more information.