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  • #210 A Personal Journey: My Decision to Quit THC

    #210 A Personal Journey: My Decision to Quit THC
    2026/01/29
    In this podcast episode, the speaker shares his personal journey of quitting THC, explaining his reasons, the gradual process over several years, and the impacts on his life. He recounts his history with THC, from early recreational use to daily dependence for sleep aid during medical school and residency. The speaker emphasizes that he does not oppose cannabis, recognizing its medicinal value, but wanted to overcome his dependency. He details his method of reducing THC use through vaping and CBD alternatives, ultimately leading to his last use in January 2025. Alongside his personal story, he discusses the benefits and potential negative impacts of THC and other cannabinoids, offering insights into who might consider quitting and why. Cannabis, THC & Quitting Cannabis (Marijuana) — NIDA overview: https://nida.nih.gov/research-topics/cannabis-marijuana Cannabis Use Disorder — NCBI Bookshelf (StatPearls): https://www.ncbi.nlm.nih.gov/books/NBK538131/ Sleep, REM & Withdrawal Cannabis and sleep architecture — systematic review (PubMed): https://pubmed.ncbi.nlm.nih.gov/40967124/ Effects of cannabinoids on sleep — review (PMC): https://pmc.ncbi.nlm.nih.gov/articles/PMC8116407/ Non-Intoxicating Cannabinoids Mentioned CBD + anxiety — systematic review (PMC): https://pmc.ncbi.nlm.nih.gov/articles/PMC11595441/ CBG — acute effects + cognition (PMC): https://pmc.ncbi.nlm.nih.gov/articles/PMC11246434/ THCV — overview/commentary (PubMed): https://pubmed.ncbi.nlm.nih.gov/33526143/ CBC — therapeutic potential review (PMC): https://pmc.ncbi.nlm.nih.gov/articles/PMC11493452/ Potency: Concentrates Marijuana Concentrates — NIDA DrugFacts PDF: https://nida.nih.gov/sites/default/files/df-marijuana-concentrates.pdf Supplements Mentioned Omega-3 Fatty Acids — NIH ODS (Consumer): https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer/ Vitamin D — NIH ODS (Consumer): https://ods.od.nih.gov/factsheets/VitaminD-Consumer/ Show Notes 00:00 Introduction: Why I Quit THC 02:18 My History with THC 06:10 Transition to Medical Use 13:53 The Quitting Process 20:11 Benefits and Challenges of Quitting 25:07 Thoughts on THC and Other Cannabinoids 33:25 Conclusion and Final Thoughts The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being. Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart
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    34 分
  • #209 Advanced Healing and Prevention Techniques with Stem Cells and Peptides

    #209 Advanced Healing and Prevention Techniques with Stem Cells and Peptides
    2026/01/22
    Most people think they go into your body and make all new tissue… but in actuality, they are a delivery mechanism of growth factors. I call them the ultimate traffic cop. In this episode, the host converses with Dr. Jesse Morse, a physician specializing in regenerative and anti-aging medicine. They delve into the intricacies of stem cells and their various sources, including bone marrow, fat, and donor tissue. Dr. Morse highlights the role of exosomes and growth factors in the healing process. The discussion also focuses on the prevention and treatment of Achilles tendon tears, emphasizing the importance of blood supply, proper diagnosis, and innovative therapies. Additionally, they explore the benefits and applications of various peptides, including BPC 157, TB 500, and MotC, for enhancing healing, anti-aging, and overall health. Dr. Morse also addresses the significance of nutrition and detoxification in maintaining optimal health and preventing injuries. Dr. Jesse Morse is a Miami-based, double board-certified physician in Family and Sports Medicine who specializes in regenerative medicine, injury recovery, and longevity. Since shifting from traditional sports medicine in 2020, he has focused on non-surgical approaches to tendon and ligament injuries using therapies like PRP, stem-cell–based treatments, exosomes, and peptides, alongside functional and anti-aging strategies centered on mitochondrial health, immune support, toxin reduction, and personalized recovery—helping everyone from active adults to high-performance athletes restore function and prevent major injuries like Achilles tears while educating widely online. Connect with him on: Instagram: https://www.instagram.com/drjessemorse/ — Sports medicine, regenerative medicine & insights Linktree (aggregated links to socials & resources): https://linktr.ee/DrJesseMorse Supplements, Compounds & Peptides Collagen (protein / connective tissue support): https://www.ncbi.nlm.nih.gov/books/NBK507922/ Vitamin C (collagen activation / antioxidant): https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/ Creatine (muscle & mitochondrial support): https://ods.od.nih.gov/factsheets/Creatine-HealthProfessional/ BPC-157 (peptide – tendon & gut healing): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504390/ TB-500 / Thymosin Beta-4 (peptide – tissue repair): https://pubmed.ncbi.nlm.nih.gov/22674782/ GHK-Cu (copper peptide – skin, joints, stem-cell signaling): https://pubchem.ncbi.nlm.nih.gov/compound/GHK-Cu MOTS-c (mitochondrial peptide): https://pubmed.ncbi.nlm.nih.gov/25174616/ SS-31 / Elamipretide (mitochondrial peptide): https://pubmed.ncbi.nlm.nih.gov/29515116/ Thymosin Alpha-1 (immune modulation peptide): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367996/ LL-37 (antimicrobial / immune peptide): https://pubmed.ncbi.nlm.nih.gov/15184378/ 5-Amino-1MQ (NNMT inhibitor / fat loss): https://pubchem.ncbi.nlm.nih.gov/compound/5-Amino-1MQ N-Acetylcysteine (NAC – liver & detox support): https://www.ncbi.nlm.nih.gov/books/NBK537183/ Glutathione (antioxidant / detox): https://ods.od.nih.gov/factsheets/Glutathione-HealthProfessional/ NAD⁺ / NMN / NR (mitochondrial & anti-aging support): NMN: https://pubchem.ncbi.nlm.nih.gov/compound/Nicotinamide-mononucleotide NR: https://pubchem.ncbi.nlm.nih.gov/compound/Nicotinamide-riboside Regenerative & Injection Therapies PRP – Platelet-Rich Plasma: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990861/ Bone Marrow–Derived Stem Cells (BMAC): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630382/ Adipose-Derived Stem Cells: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416130/ Amniotic / Placental Tissue Products: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124018/ Exosomes (cell signaling vesicles): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465611/ Ultrasound-Guided Injections: https://radiopaedia.org/articles/musculoskeletal-ultrasound-guided-injection Needle Tenotomy (scar-tissue disruption): https://pubmed.ncbi.nlm.nih.gov/30428129/ Detox, Blood & Environmental Interventions Sauna (heat detox & cardiovascular benefit): https://www.health.harvard.edu/staying-healthy/saunas-and-your-health Binders – Modified Citrus Pectin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452227/ GI Detox / Toxin Binders (general concept): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654245/ Heavy Metal Chelation (DMPS concept): https://pubmed.ncbi.nlm.nih.gov/12198644/ Mercury Toxicity: https://www.cdc.gov/mercury/index.html Microplastics in Humans: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068600/ EBOO Therapy (ozone-based blood filtration): https://pubmed.ncbi.nlm.nih.gov/36681461/ Therapeutic Plasma Exchange (TPE): https://www.ncbi.nlm.nih.gov/books/NBK557561/ INUSpheresis (advanced plasma filtration): https://pubmed.ncbi.nlm.nih.gov/37324197/ Medications & Drug Classes Mentioned Corticosteroids (Prednisone – tendon risk): https://medlineplus.gov/druginfo/meds/a601102.html ...
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    1 時間 6 分
  • #208 The Real Science Behind Detoxification: Liver, Kidneys, and Gut Health Explained

    #208 The Real Science Behind Detoxification: Liver, Kidneys, and Gut Health Explained
    2026/01/15
    Most "detox" advice focuses on cleanses and quick fixes — but real detoxification is a constant, biological process your body runs every day. In this solo episode, the host breaks down how detoxification actually works, starting with what counts as a "toxin" (including hormones and environmental chemicals) and how the body packages them for elimination. You'll learn the key roles of the liver, kidneys, and gut — and why detox can succeed in the liver but fail in the intestines, especially when certain gut bacteria produce enzymes like β-glucuronidase that can send toxins back into circulation. The episode covers major detox pathways (including glucuronidation), the importance of bile flow and regular bowel movements, and why fiber is one of the biggest levers you can pull to support elimination. It also explores how hydration, electrolyte balance, stress, and overtraining can influence detox capacity, plus the limited-but-real role sweating may play in clearing certain heavy metals. Finally, you'll get practical strategies for supporting a healthier gut microbiome and reducing toxin buildup — from diet and polyphenols to commonly discussed supplements like NAC, glycine, and taurine. Supplements & Compounds Magnesium (supplement/mineral): https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/ Zinc (supplement/mineral): https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/ Psyllium (fiber / bulk-forming laxative): https://medlineplus.gov/druginfo/meds/a601104.html Spirulina (supplement / "blue-green algae"): https://www.ncbi.nlm.nih.gov/books/NBK548312/ Activated Charcoal (binder / poisoning use): https://pmc.ncbi.nlm.nih.gov/articles/PMC6620762/ Glycine (amino acid): https://pubchem.ncbi.nlm.nih.gov/compound/Glycine N-Acetylcysteine (NAC): https://www.ncbi.nlm.nih.gov/books/NBK537183/ Foods / Gut & Microbiome Mentions Fermented foods (kimchi, sauerkraut, etc.): https://health.clevelandclinic.org/5-reasons-you-should-add-more-fermented-foods-to-your-diet-infographic Kimchi (specific fermented food mentioned): https://health.clevelandclinic.org/is-kimchi-good-for-you Sourdough (food example mentioned): https://en.wikipedia.org/wiki/Sourdough Berries (food example mentioned): https://en.wikipedia.org/wiki/Berry Wild rice (food example mentioned): https://en.wikipedia.org/wiki/Wild_rice Medications Mentioned Ibuprofen (Advil): https://medlineplus.gov/druginfo/meds/a682159.html Naproxen (NSAID): https://medlineplus.gov/druginfo/meds/a681029.html Lifestyle / Modalities Mentioned Sauna: https://www.health.harvard.edu/staying-healthy/saunas-and-your-health Infrared sauna: https://health.clevelandclinic.org/infrared-sauna-benefits Red light therapy (photobiomodulation): https://my.clevelandclinic.org/health/articles/22114-red-light-therapy Environmental / Exposure Topics Mentioned BPA (bisphenol A): https://www.niehs.nih.gov/health/topics/agents/sya-bpa Phthalates: https://wwwn.cdc.gov/tsp/substances/ToxChemicalListing.aspx?toxid=41 Lead exposure: https://www.cdc.gov/lead-prevention/prevention/index.html Arsenic in rice: https://www.fda.gov/food/environmental-contaminants-food/what-you-can-do-limit-exposure-arsenic Key Mechanism/Concept Mentioned Gut microbial β-glucuronidase (and "glucuronidation" talk): https://pmc.ncbi.nlm.nih.gov/articles/PMC9717552/ Show Notes 00:00 Introduction to Detoxification 02:00 Understanding Toxins and Hormones 05:36 Common Environmental Toxins 07:10 The Detoxification Process 10:52 Gut Health and Detoxification 20:07 Sweating and Detoxification 23:35 Supplements for Detoxification 29:31 Conclusion and Final Tips The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make ...
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    30 分
  • #207 Mastering Hydration: The Essential Guide to Water, Electrolytes, and Optimal Performance

    #207 Mastering Hydration: The Essential Guide to Water, Electrolytes, and Optimal Performance
    2026/01/08
    What if your "healthy" water intake is still quietly hurting your performance? In this solo episode, Dr. Mike breaks down hydration from a performance-first perspective — how dehydration affects cognition and physical output, why "8 glasses a day" is an oversimplified myth, and how to personalize your intake based on body size, activity level, diet, environment, and medications. He walks through practical guidelines (including 30–35 ml/kg/day), how to use urine + thirst cues without overcomplicating it, and why timing matters (especially around workouts, sauna use, and sleep). A major focus of this episode is electrolytes — what they do, how sweat changes your needs, and why sodium is often the key limiter for athletes, sauna users, and people eating low-carb/keto. Dr. Mike also covers potassium and magnesium, caffeine and hydration, the risks of overhydration, and the classic warning signs of hyponatremia. This is a comprehensive, no-BS guide to staying hydrated, replenishing electrolytes correctly, and improving energy, performance, and sleep. Resources: Electrolyte & Hydration Products LMNT Official Home Page: https://drinklmnt.com/ LMNT Recharge Electrolyte Drink Mix: https://drinklmnt.com/products/lmnt-recharge-electrolyte-drink LMNT Variety Pack: https://drinklmnt.com/products/lmnt-recharge-variety-pack DIY Homemade Electrolyte Drink (LMNT Science): https://science.drinklmnt.com/electrolytes/best-homemade-electrolyte-drink-for-dehydration Gatorade Electrolyte Powder for Hydration (Official): https://www.gatorade.com/powders Medical / Health Conditions & Guidance Hyponatremia — Symptoms & Causes (Mayo Clinic): https://www.mayoclinic.org/diseases-conditions/hyponatremia/symptoms-causes/syc-20373711 Hyponatremia — Diagnosis & Treatment (Mayo Clinic): https://www.mayoclinic.org/diseases-conditions/hyponatremia/diagnosis-treatment/drc-20373715 Lab Tests Magnesium, RBC (Labcorp): https://www.labcorp.com/tests/080283/magnesium-rbc Mineral / Supplement References Magnesium — Fact Sheet for Health Professionals (NIH ODS): https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/ Potassium — Fact Sheet for Health Professionals (NIH ODS): https://ods.od.nih.gov/factsheets/Potassium-HealthProfessional/ Dietary Supplements for Exercise and Athletic Performance — Fact Sheet for Health Professionals (NIH ODS): https://ods.od.nih.gov/factsheets/ExerciseAndAthleticPerformance-HealthProfessional/ People / Sources Mentioned Robb Wolf (LMNT Science author page): https://science.drinklmnt.com/authors/robb-wolf Robb Wolf (official site): https://robbwolf.com/ Huberman Lab (official site): https://www.hubermanlab.com Show Notes 00:00 Welcome Back to the Hart2Heart Podcast! 00:55 The Importance of Hydration 01:46 Daily Water Intake Guidelines 04:16 Sweat and Electrolyte Loss 06:56 Sodium: The Key Electrolyte 12:22 Potassium: Essential for Muscle and Heart Health 15:20 Magnesium: The Multi-Functional Mineral 20:08 Other Important Nutrients 22:33 Hydration Strategies and Special Populations 26:37 Final Tips and Conclusion The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being. Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart
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    31 分
  • #206 How to Fix High Blood Pressure (Without Guessing)

    #206 How to Fix High Blood Pressure (Without Guessing)
    2026/01/02
    In this solo episode, Dr. Mike breaks down everything you need to know about blood pressure, why it's so commonly misunderstood, how to measure it correctly, and what optimal numbers really look like. He explains why 120/80 isn't ideal for everyone, why blood pressure variability can be more dangerous than steady high readings, and how sleep, stress, and undiagnosed sleep apnea quietly drive hypertension. The episode walks through a clear, practical framework for managing blood pressure using lifestyle interventions first, followed by supplements, and medications only when necessary. Dr. Mike covers exercise, weight loss, sodium and potassium balance, magnesium, breathing techniques, sauna use, sleep optimization, and evidence-based supplements like olive leaf extract, beetroot, citrulline, and nattokinase. He also explains when medication is appropriate, why ARBs are often preferred, and which drugs can interfere with exercise performance. This is a comprehensive, no-BS guide to protecting your heart, brain, kidneys, and long-term health. Blood Pressure & Monitoring Ambulatory Blood Pressure Monitoring (ABPM): https://www.heart.org/en/health-topics/high-blood-pressure/understanding-blood-pressure-readings/ambulatory-blood-pressure-monitoring How to Measure Blood Pressure Correctly at Home: https://www.heart.org/en/health-topics/high-blood-pressure/understanding-blood-pressure-readings/monitoring-your-blood-pressure-at-home Sleep Apnea & Blood Pressure Sleep Apnea and High Blood Pressure (AHA): https://www.heart.org/en/health-topics/high-blood-pressure/why-high-blood-pressure-is-a-silent-killer/sleep-apnea-and-high-blood-pressure Sleep Apnea Testing Overview: https://sleepeducation.org/patients/sleep-apnea/ Supplements Discussed Olive Leaf Extract (NIH): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452224/ Magnesium and Blood Pressure (NIH): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452224/ Beetroot, Nitric Oxide, and Blood Pressure: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723444/ L-Citrulline and Blood Pressure: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368575/ Nattokinase and Cardiovascular Health: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043915/ Medications (General Reference) Angiotensin Receptor Blockers (ARBs): https://www.ncbi.nlm.nih.gov/books/NBK459131/ Calcium Channel Blockers: https://www.ncbi.nlm.nih.gov/books/NBK482473/ Thiazide Diuretics: https://www.ncbi.nlm.nih.gov/books/NBK470415/ Show Notes 00:00 Welcome to the Hart2Heart Podcast. 02:15 Why 120/80 isn't optimal for everyone 04:15 What actually causes blood pressure to fluctuate 06:40 Why BP variability is more dangerous than steady high BP 07:30 How to measure blood pressure correctly at home 12:45 Nighttime BP, dippers vs non-dippers (and why it matters) 14:00 Sleep apnea: the hidden driver of hypertension 18:30 The lifestyle changes that lower BP the most 21:00 Electrolytes, magnesium, and nervous system control 26:00 Supplements that actually move the needle 31:25 When medication becomes necessary (and when it doesn't) 36:20 The long-term blood pressure strategy most people miss The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box physicians and researchers to public health experts and high-profile thinkers focused on real solutions. If you're ready to take control of your health and performance, this podcast is for you. Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart
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    37 分
  • #205 Stop Nighttime Peeing

    #205 Stop Nighttime Peeing
    2025/12/25

    In this solo episode, Dr. Mike discusses the common issue of nocturia, where individuals frequently wake up at night to urinate, which disrupts sleep. The episode covers the root causes including sleep apnea, enlarged prostate, and overactive bladder, and dives into the roles of antidiuretic hormone (ADH) and atrial natriuretic peptide (ANP). It provides a comprehensive guide on addressing nocturia through behavioral modifications such as fluid restriction and sleep hygiene, supplements like pumpkin seed extract and beta-sitosterol, and pharmaceuticals including Desmopressin and alpha-blockers. The host also touches on treating sleep apnea with CPAP machines and mandibular advancement devices, emphasizing the importance of targeting the root cause for effective treatment.

    Links:

    CPAP (Continuous Positive Airway Pressure) Beta-Sitosterol Desmopressin (Synthetic ADH)

    Show Notes:

    00:00 Understanding nocturia and its connection to sleep apnea

    01:00 Introduction and episode overview

    02:00 Defining nocturia and its impact on sleep

    03:00 Types of nocturia and their causes

    04:30 The role of hormones in nocturia

    05:30 Sleep apnea and its effects on nocturia

    15:30 Behavioral modifications to reduce nocturia

    24:00 Supplements for managing nocturia

    30:00 Pharmaceutical solutions for nocturia

    —

    The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to

    cutting through the noise and uncovering the most effective strategies for optimizing health,

    longevity, and peak performance. This podcast dives deep into evidence-based approaches to

    hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise

    protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.

    Beyond health science, we tackle the intersection of public health and politics, exposing how

    policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.

    Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary

    (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as

    Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).

    If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.

    Connect on social with Dr. Mike Hart:

    • Instagram: @drmikehart

    • Twitter: @drmikehart

    • Facebook: @drmikehart
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    41 分
  • #204 Resetting Dopamine for Monogamy

    #204 Resetting Dopamine for Monogamy
    2025/12/11

    In this solo episode, Dr. Mike delves into the complex relationship between dopamine, romantic relationships, and the Coolidge Effect. The discussion highlights why men often feel the need for a new partner due to a desensitization of dopamine and how our overstimulated lifestyles contribute to this issue. The host explores the impact of modern habits on dopamine levels, the importance of boredom for resetting dopamine sensitivity, and the role of anticipation in maintaining desire. Practical solutions like dopamine resets, engaging in effort-based activities, and ensuring personal growth and solitude are discussed as ways to improve both individual well-being and relationship satisfaction.

    Links:

    The Dopamine Collapse Hypothesis: Foundations of Macro-Neuroeconomics

    Show Notes:

    00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart

    01:30 Understanding the dopamine cycle 03:30 Daily habits and dopamine desensitization 09:00 The Coolidge effect and relationship dynamics 15:00 Dopamine resets and effort-based activities 22:00 Reviving desire in long-term relationships

    28:38 "Our nervous system never gets any time to recover—and that kills desire."

    —

    The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to

    cutting through the noise and uncovering the most effective strategies for optimizing health,

    longevity, and peak performance. This podcast dives deep into evidence-based approaches to

    hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise

    protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.

    Beyond health science, we tackle the intersection of public health and politics, exposing how

    policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.

    Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary

    (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as

    Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).

    If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.

    Connect on social with Dr. Mike Hart:

    • Instagram: @drmikehart

    • Twitter: @drmikehart

    • Facebook: @drmikehart
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    29 分
  • #203 Rethinking 10k Steps

    #203 Rethinking 10k Steps
    2025/12/04

    In this episode, Dr. Mike Hart delves into the origins and contemporary relevance of the 10,000 steps rule. He discusses the latest research outcomes from a massive meta-analysis comparing daily step counts from 2,000 to 12,000 steps and their associated health benefits. Listeners will learn about the significant reductions in mortality, cardiovascular disease, cancer mortality, dementia, depression, and type 2 diabetes risk achieved by increasing daily steps. The episode also provides insights into the importance of breaking up sedentary periods, the physiological differences between various forms of steps, and practical tips for incorporating more steps into daily routines, even for office workers.

    Links:

    Massive Steps Meta-analysis

    Show Notes:

    (00:00) Welcome back to the Hart2Heart Podcast with Dr. Mike Hart

    (01:30) Origins of the 10,000 steps rule (03:00) Latest research on step counts

    (06:34) "Each 1,000 steps lowers your chance of depression by about 9%."

    (08:00) Steps vs. exercise: understanding the difference (21:30) Practical tips for increasing daily steps

    —

    The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to

    cutting through the noise and uncovering the most effective strategies for optimizing health,

    longevity, and peak performance. This podcast dives deep into evidence-based approaches to

    hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise

    protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.

    Beyond health science, we tackle the intersection of public health and politics, exposing how

    policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.

    Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary

    (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as

    Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).

    If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.

    Connect on social with Dr. Mike Hart:

    • Instagram: @drmikehart

    • Twitter: @drmikehart

    • Facebook: @drmikehart
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