In Episode 6, we go deeper into cannabis, not as a single drug, but as an ecosystem of molecules.

We explore the nuanced chemistry behind the entourage effect. How cannabinoids like THC & CBD interact with aromatic terpenes like limonene and myrcene to shape mood, memory, and perception. It's not just what’s in the plant, it’s how the molecules communicate.

Because cannabis isn’t one voice.It’s a chorus.And the body doesn’t just receive it passively: it listens, filters, and responds.

This episode covers:

🌿 The major cannabinoids and what they do (scientifically, not sensationally)🎺 Why whole-plant medicine feels different than isolates🌱 How terpenes function like emotional context, not just scent🧬 The biological logic of synergy and polypharmacology in action⚖️ And why effects are relational, not linear

We also reflect on what it means to listen to the plant not just biochemically, but culturally.

🔓 Paid subscribers get the full episode script + citations + notes.

As always, Green Gage’s is ad-free, algorithm-free, and built for people who believe consciousness deserves careful language.

Thanks for listening, reading, and thinking with me.

This episode is for educational purposes only. It is intended for mature audiences and explores scientific, historical, and cultural perspectives on psychoactive substances. Nothing in this content should be interpreted as medical advice or encouragement for illegal activity. Viewers are responsible for knowing and following their local laws. If you or someone you know is struggling with substance use or mental health, please seek support from a qualified healthcare provider.

THC and anandamide. One from the plant. One from the brain. Both speak the same chemical language.

In this episode, we take a closer look at two molecular messengers: THC, the psychoactive compound in cannabis, and anandamide, its naturally occurring counterpart in the human brain.

What do these two molecules reveal about memory, motivation, and mood? And what happens when balance between them is lost?

We explore how both compounds interact with the endocannabinoid system, not to override it, but to tune it. And in doing so, we trace the fine line between euphoria and dysregulation, between enhancement and escape.

In this episode, we cover:• How THC and anandamide compare structurally and functionally• Why cannabis feels so familiar to the brain• The role of anandamide in stress recovery, memory, and pleasure• How THC mimics, amplifies, and sometimes disrupts the ECS• The science of balance and what long-term cannabis use may do to it• A reframe of cannabis: not just a substance, but a signal

This episode lays the groundwork for understanding cannabis not as a single effect, but as a spectrum and how context, chemistry, and internal state all shape the outcome.

Green Gage’s is a 44-part exploration of consciousness through the lens of chemistry, neuroscience, and poetic insight.

🔎 Keywords: THC vs anandamide, cannabis science, endocannabinoid system, how THC works, natural cannabinoids, cannabis and memory, neurochemistry podcast, ECS modulation, Green Gage’s, psychoactive balance, cannabinoid receptors

📥 Follow & Subscribe for weekly episodes.**📩 Share your thoughts, questions, or reflections in the comments.

Welcome to Green Gage’s. Let’s begin.

This episode is for educational purposes only. It is intended for mature audiences and explores scientific, historical, and cultural perspectives on psychoactive substances. Nothing in this content should be interpreted as medical advice or encouragement for illegal activity. Viewers are responsible for knowing and following their local laws. If you or someone you know is struggling with substance use or mental health, please seek support from a qualified healthcare provider.

A system hidden in plain sight. A molecule named after bliss. A plant that revealed it all.

Welcome to Episode 4 of thegreengage a podcast exploring the secret symphony of nature, mind, and science.

In this episode, we trace the astonishing story of the endocannabinoid system a vast, overlooked regulatory network inside the human body, first discovered because of cannabis.

From underground labs in 1960s Israel to breakthrough receptor mapping in the U.S., we follow how the study of THC led to the discovery of a system built not for intoxication, but for balance.

In this episode, we cover:• The discovery of THC and the mystery of how it worked• The emergence of CB1 and CB2 receptors in the brain and immune system• The brain’s own cannabis-like molecules: anandamide and 2-AG• How the ECS maintains internal balance: from stress to sleep to inflammation• Why cannabis acts not as an invader, but as a mirror of our internal intelligence• The clinical relevance of ECS dysregulation and its role in resilience

This is not just a story about a plant. It’s a story about how a plant helped science rediscover the body’s own language of equilibrium.

Green Gage’s is a 44-part journey into the chemistry of being — blending neuroscience, story, and psychoactive insight.

🔎 Keywords: endocannabinoid system, THC receptors, anandamide, what is ECS, cannabis and homeostasis, neuroscience podcast, psychoactive systems, CB1 CB2 explained, bliss molecule, resilience biology, Green Gage’s

📥 Follow & Subscribe for weekly episodes.**📩 Share your questions or reflections in the comments.

Welcome to Green Gage’s. Let’s begin.