Nesse episódio terminamos o raciocínio que começamos na parte 1, sobre o significado de dizer que o corpo "quer" reparar algo, o músculo "quer" crescer, entre outras afirmações didáticas.

Refs.:

ALBERTS, Bruce et al. Molecular biology of the cell. 6. ed. New York: Garland Science, 2014.

ARISTÓTELES. De anima. [S.l.]: [s.n.], [s.d.].

ARISTÓTELES. Física. Livro II. [S.l.]: [s.n.], [s.d.].

BARRETT, Lisa Feldman. How emotions are made: the secret life of the brain. Boston: Houghton Mifflin Harcourt, 2017.

BERTALANFFY, Ludwig von. General system theory: foundations, development, applications. New York: George Braziller, 1968.

CANNON, Walter Bradford. The wisdom of the body. New York: W. W. Norton, 1932.

DARWIN, Charles. On the origin of species by means of natural selection, or, the preservation of favoured races in the struggle for life. London: John Murray, 1859.

DAWKINS, Richard. The blind watchmaker. Harlow: Longman Scientific & Technical,1986.

FRISTON, Karl. The free-energy principle: a unified brain theory? Nature Reviews Neuroscience, v. 11, n. 2, p. 127–138, 2010. DOI: 10.1038/nrn2787.

KAUFFMAN, Stuart A. The origins of order: self-organization and selection in evolution. New York: Oxford University Press, 1993.

LODISH, Harvey et al. Molecular cell biology. 8. ed. New York: W. H. Freeman; Macmillan Learning, 2016.

MAYNARD SMITH, John. The concept of information in biology. Philosophy of Science, v. 67, n. 2, p. 177–194, 2000. DOI: 10.1086/392768.

MAYR, Ernst. The growth of biological thought: diversity, evolution, and inheritance. Cambridge, MA: Harvard University Press, 1982.

MAYR, Ernst. Toward a new philosophy of biology: observations of an evolutionist. Cambridge, MA: Harvard University Press, 1988.

NEANDER, Karen. Functions as selected effects: the conceptual analyst's defense. Philosophy of Science, v. 58, n. 2, p. 168–184, 1991. DOI: 10.1086/289610.

PRIGOGINE, Ilya; STENGERS, Isabelle. Order out of chaos: man's new dialogue with nature. New York: Bantam Books, 1984..

SHANNON, Claude E. A mathematical theory of communication. Bell System Technical Journal, v. 27, n. 3, p. 379–423, 1948. DOI: 10.1002/j.1538-7305.1948.tb01338.x.

STERLING, Peter. Allostasis: a model of predictive regulation. Physiology & Behavior, v. 106, n. 1, p. 5–15, 2012. DOI: 10.1016/j.physbeh.2011.06.004.

STERLING, Peter. What is health? Allostasis and the evolution of human design. Cambridge, MA: MIT Press, 2020.

WILLIAMS, George C. Adaptation and natural selection: a critique of some current evolutionary thought. Princeton: Princeton University Press, 1966.

WRIGHT, Larry. Functions. The Philosophical Review, v. 82, n. 2, p. 139–168, 1973. DOI: 10.2307/2183766.

Se deseja marcar uma consulta, mande mensagem no email profbaeta@gmail.com ou entre no site www.lucabaeta.com.br ou ainda, se preferir, mande mensagem no instagram @profbaeta

Neste episódio, discutimos sobre o significado de dizer que o corpo "quer" reparar algo, o músculo "quer" crescer, entre outras afirmações didáticas.

Refs.:

ALBERTS, Bruce et al. Molecular biology of the cell. 6. ed. New York: Garland Science, 2014. A 6ª edição foi publicada pela Garland Science em 2014.

ARISTÓTELES. De anima. [S.l.]: [s.n.], [s.d.].

ARISTÓTELES. Física. Livro II. [S.l.]: [s.n.], [s.d.].

BARRETT, Lisa Feldman. How emotions are made: the secret life of the brain. Boston: Houghton Mifflin Harcourt, 2017.

BERTALANFFY, Ludwig von. General system theory: foundations, development, applications. New York: George Braziller, 1968. A obra é a formulação clássica da teoria geral dos sistemas de von Bertalanffy.

CANNON, Walter Bradford. The wisdom of the body. New York: W. W. Norton, 1932.

DARWIN, Charles. On the origin of species by means of natural selection, or, the preservation of favoured races in the struggle for life. London: John Murray, 1859.

DAWKINS, Richard. The blind watchmaker. Harlow: Longman Scientific & Technical, 1986.

FRISTON, Karl. The free-energy principle: a unified brain theory? Nature Reviews Neuroscience, v. 11, n. 2, p. 127–138, 2010. DOI: 10.1038/nrn2787.

KAUFFMAN, Stuart A. The origins of order: self-organization and selection in evolution. New York: Oxford University Press, 1993.

LODISH, Harvey et al. Molecular cell biology. 8. ed. New York: W. H. Freeman; Macmillan Learning, 2016.

MAYNARD SMITH, John. The concept of information in biology. Philosophy of Science, v. 67, n. 2, p. 177–194, 2000. DOI: 10.1086/392768.

MAYR, Ernst. The growth of biological thought: diversity, evolution, and inheritance. Cambridge, MA: Harvard University Press, 1982.

MAYR, Ernst. Toward a new philosophy of biology: observations of an evolutionist. Cambridge, MA: Harvard University Press, 1988.

NEANDER, Karen. Functions as selected effects: the conceptual analyst's defense. Philosophy of Science, v. 58, n. 2, p. 168–184, 1991. DOI: 10.1086/289610.

PRIGOGINE, Ilya; STENGERS, Isabelle. Order out of chaos: man's new dialogue with nature. New York: Bantam Books, 1984. A obra foi publicada originalmente em inglês em 1984 e é de autoria conjunta de Prigogine e Stengers.

SHANNON, Claude E. A mathematical theory of communication. Bell System Technical Journal, v. 27, n. 3, p. 379–423, 1948. DOI: 10.1002/j.1538-7305.1948.tb01338.x.

STERLING, Peter. Allostasis: a model of predictive regulation. Physiology & Behavior, v. 106, n. 1, p. 5–15, 2012. DOI: 10.1016/j.physbeh.2011.06.004.

STERLING, Peter. What is health? Allostasis and the evolution of human design. Cambridge, MA: MIT Press, 2020.

WILLIAMS, George C. Adaptation and natural selection: a critique of some current evolutionary thought. Princeton: Princeton University Press, 1966.

WRIGHT, Larry. Functions. The Philosophical Review, v. 82, n. 2, p. 139–168, 1973. DOI: 10.2307/2183766.

Neste episódio vimos como o metabolismo é muito mais sofisticado do que o senso comum, que tenta simplificá-lo em "transformar comida em energia", entre outras reduções que não fazem jus!

Refs.:

ALON, Uri. An Introduction to Systems Biology: Design Principles of Biological Circuits. 2. ed. Boca Raton: Chapman & Hall/CRC, 2019.

BALCH, William E.; MORIMOTO, Richard I.; DILLIN, Andrew; KELLY, Jeffery W. Adapting proteostasis for disease intervention. Science, Washington, v. 319, n. 5865, p. 916–919, 2008. DOI: https://doi.org/10.1126/science.1141448

BASS, Joseph; TAKAHASHI, Joseph S. Circadian integration of metabolism and energetics. Science, Washington, v. 330, n. 6009, p. 1349–1354, 2010. DOI: https://doi.org/10.1126/science.1195027

BECHTEL, William. Discovering Cell Mechanisms: The Creation of Modern Cell Biology. Cambridge: Cambridge University Press, 2006.

GUYTON, Arthur C.; HALL, John E. Tratado de Fisiologia Médica. 14. ed. Rio de Janeiro: Elsevier, 2021.

HARDIE, D. Grahame. AMP-activated protein kinase: maintaining energy homeostasis at the cellular and whole-body levels. Annual Review of Nutrition, Palo Alto, v. 34, p. 31–55, 2014. DOI: https://doi.org/10.1146/annurev-nutr-071812-161148

HARDIE, D. Grahame. AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nature Reviews Molecular Cell Biology, London, v. 8, n. 10, p. 774–785, 2007. DOI: https://doi.org/10.1038/nrm2249

INGBER, Donald E. Mechanobiology and diseases of mechanotransduction. Annals of Medicine, London, v. 35, n. 8, p. 564–577, 2003. DOI: https://doi.org/10.1080/07853890310016333

KITANO, Hiroaki. Systems biology: a brief overview. Science, Washington, v. 295, n. 5560, p. 1662–1664, 2002. DOI: https://doi.org/10.1126/science.1069492

KIRKWOOD, Thomas B. L. Evolution of ageing. Nature, London, v. 270, p. 301–304, 1977. DOI: https://doi.org/10.1038/270301a0

LÓPEZ-OTÍN, Carlos et al. Hallmarks of aging: an expanding universe. Cell, Cambridge, v. 186, n. 2, p. 243–278, 2023. DOI: https://doi.org/10.1016/j.cell.2022.11.001

NICHOLLS, David G.; FERGUSON, Stuart J. Bioenergetics. 4. ed. London: Academic Press, 2013.

NOBLE, Denis. The Music of Life: Biology Beyond Genes. Oxford: Oxford University Press, 2006.

OHSUMI, Yoshinori. Historical landmarks of autophagy research. Cell Research, Shanghai, v. 24, n. 1, p. 9–23, 2014. DOI: https://doi.org/10.1038/cr.2013.169

PRIGOGINE, Ilya; STENGERS, Isabelle. Order Out of Chaos: Man's New Dialogue with Nature. New York: Bantam Books, 1984.

SAXTON, Robert A.; SABATINI, David M. mTOR signaling in growth, metabolism, and disease. Cell, Cambridge, v. 168, n. 6, p. 960–976, 2017. DOI: https://doi.org/10.1016/j.cell.2017.02.004

SCHRÖDINGER, Erwin. What is Life? The Physical Aspect of the Living Cell. Cambridge: Cambridge University Press, 1944.

SHANNON, Claude E. A mathematical theory of communication. Bell System Technical Journal, New York, v. 27, n. 3, p. 379–423, 1948. DOI: https://doi.org/10.1002/j.1538-7305.1948.tb01338.x

SIMON, Herbert A. The Sciences of the Artificial. 3. ed. Cambridge: MIT Press, 1996.

SINCLAIR, David A.; GUARENTE, Leonard. Small-molecule allosteric activators of sirtuins. Annual Review of Pharmacology and Toxicology, Palo Alto, v. 54, p. 363–380, 2014. DOI: https://doi.org/10.1146/annurev-pharmtox-010611-134657

STERLING, Peter. What Is Health? Allostasis and the Evolution of Human Design. Cambridge: MIT Press, 2020.

VON NEUMANN, John. Theory of Self-Reproducing Automata. Urbana: University of Illinois Press, 1966.

WEST, Geoffrey. Scale: The Universal Laws of Life, Growth, and Death in Organisms, Cities, and Companies. New York: Penguin Press, 2017.

Se deseja marcar uma consulta, mande mensagem no email profbaeta@gmail.com ou entre no site www.lucabaeta.com.br ou ainda, se preferir, mande mensagem no instagram @profbaeta

Neste episódio falamos sobre alguns mecanismos de dor, adaptação, inflamação e como isso tudo se relaciona com o nosso corpo ficando mais forte ou mais adaptado.

Refs.:

Bodine SC, Stitt TN, et al. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol. 2001 Nov;3(11):1014-9. doi: 10.1038/ncb1101-1014. PMID: 11715023.

Booth FW, Roberts CK, Laye MJ. Lack of exercise is a major cause of chronic diseases. Compr Physiol. 2012 Apr;2(2):1143-211. doi: 10.1002/cphy.c110025. PMID: 23798298; PMCID: PMC4241367.

Calabrese EJ, Mattson MP. Hormesis provides a generalized quantitative estimate of biological plasticity. J Cell Commun Signal. 2011 Mar;5(1):25-38. doi: 10.1007/s12079-011-0119-1. Epub 2011 Feb 25. PMID: 21484586; PMCID: PMC3058190.

Hornberger TA, Esser KA. Mechanotransduction and the regulation of protein synthesis in skeletal muscle. Proc Nutr Soc. 2004 May;63(2):331-5. doi: 10.1079/PNS2004357. PMID: 15294051.

Humphrey JD, Dufresne ER, Schwartz MA. Mechanotransduction and extracellular matrix homeostasis. Nat Rev Mol Cell Biol. 2014 Dec;15(12):802-12. doi: 10.1038/nrm3896. Epub 2014 Oct 22. PMID: 25355505; PMCID: PMC4513363.

Ingber DE. Mechanobiology and diseases of mechanotransduction. Ann Med. 2003;35(8):564-77. doi: 10.1080/07853890310016333. PMID: 14708967.

Lim C, Nunes EA, et al. An Evidence-Based Narrative Review of Mechanisms of Resistance Exercise-Induced Human Skeletal Muscle Hypertrophy. Med Sci Sports Exerc. 2022 Sep 1;54(9):1546-1559. doi: 10.1249/MSS.0000000000002929. Epub 2022 Apr 6. PMID: 35389932; PMCID: PMC9390238.

Mattson MP. Hormesis defined. Ageing Res Rev. 2008 Jan;7(1):1-7. doi: 10.1016/j.arr.2007.08.007. Epub 2007 Dec 5. PMID: 18162444; PMCID: PMC2248601.

Sterling P. What is Health? Allostasis and the Evolution of Human Design. MIT Press. 2020.

Su C, Zhang Z, Liang B, Zhou S, Long X. Effects of blood flow restriction combined with high-load training on muscle strength and sports performance in athletes: a systematic review and meta-analysis. Front Physiol. 2025 Jul 2;16:1603568. doi: 10.3389/fphys.2025.1603568. PMID: 40671707; PMCID: PMC12263612.

Tao R, Yang Y, Wilson M, Chang JR, Liu C, Sit CHP. Comparative effectiveness of physical activity interventions on cognitive functions in children and adolescents with Neurodevelopmental Disorders: a systematic review and network meta-analysis of randomized controlled trials. Int J Behav Nutr Phys Act. 2025 Jan 13;22(1):6. doi: 10.1186/s12966-024-01702-7. PMID: 39806448; PMCID: PMC11731537.

Wohlann T, Warneke K, et al. Influence of 8-weeks of supervised static stretching or resistance training of pectoral major muscles on maximal strength, muscle thickness and range of motion. Eur J Appl Physiol. 2024 Jun;124(6):1885-1893. doi: 10.1007/s00421-023-05413-y. Epub 2024 Jan 19. PMID: 38240811; PMCID: PMC11129965.

Zügel M, Maganaris CN, et al. Fascial tissue research in sports medicine: from molecules to tissue adaptation, injury and diagnostics: consensus statement. Br J Sports Med. 2018 Dec;52(23):1497. doi: 10.1136/bjsports-2018-099308. Epub 2018 Aug 2. PMID: 30072398; PMCID: PMC6241620.

Se deseja marcar uma consulta, mande mensagem no email profbaeta@gmail.com ou entre no site www.lucabaeta.com.br ou ainda, se preferir, mande mensagem no instagram @profbaeta

Neste episódio falamos sobre diferentes sistemas de manutenção do peso corporal.

Se deseja marcar uma consulta, mande mensagem no email profbaeta@gmail.com ou entre no site www.lucabaeta.com.br ou ainda, se preferir, mande mensagem no instagram @profbaeta

Refs.:

Hall KD, Guo J. Obesity Energetics: Body Weight Regulation and the Effects of Diet Composition. Gastroenterology. 2017 May;152(7):1718-1727.e3. doi: 10.1053/j.gastro.2017.01.052. Epub 2017 Feb 11. PMID: 28193517; PMCID: PMC5568065.

Tham KW et al. Obesity in South and Southeast Asia-A new consensus on care and management. Obes Rev. 2023 Feb;24(2):e13520. doi: 10.1111/obr.13520. Epub 2022 Dec 1. PMID: 36453081; PMCID: PMC10078503.

Rubino F et al. Joint international consensus statement for ending stigma of obesity. Nat Med. 2020 Apr;26(4):485-497. doi: 10.1038/s41591-020-0803-x. Epub 2020 Mar 4. PMID: 32127716; PMCID: PMC7154011.

García-Gómez I et al. Changes in Resting Energy Expenditure in Response to Different Dietary Patterns: A Randomized Clinical Trial Exploratory Sub-Analysis. Nutrients. 2026 Jun 24;18(13):2053. doi: 10.3390/nu18132053. PMID: 42451057; PMCID: PMC13363438.

Wilson RE, Marshall RD, Murakami JM, Latner JD. Brief non-dieting intervention increases intuitive eating and reduces dieting intention, body image dissatisfaction, and anti-fat attitudes: A randomized controlled trial. Appetite. 2020 May 1;148:104556. doi: 10.1016/j.appet.2019.104556. Epub 2020 Jan 1. PMID: 31901439.

Martins C, Roekenes J, Salamati S, Gower BA, Hunter GR. Metabolic adaptation is an illusion, only present when participants are in negative energy balance. Am J Clin Nutr. 2020 Nov 11;112(5):1212-1218. doi: 10.1093/ajcn/nqaa220. PMID: 32844188; PMCID: PMC7657334.

Perry AS, et al. The inflammatory proteome, obesity, and medical weight loss and regain in humans. Obesity (Silver Spring). 2023 Jan;31(1):150-158. doi: 10.1002/oby.23587. Epub 2022 Nov 5. PMID: 36334095; PMCID: PMC9923277.

Fothergill E, et al. Persistent metabolic adaptation 6 years after "The Biggest Loser" competition. Obesity (Silver Spring). 2016 Aug;24(8):1612-9. doi: 10.1002/oby.21538. Epub 2016 May 2. PMID: 27136388; PMCID: PMC4989512.

Neste episódio investigativo, falamos sobre como a discussão de que uma caloria não é igual a outra, sem violar as leis da Física e da termodinâmica.

Refs.:

Westerterp KR. Diet induced thermogenesis. Nutr Metab (Lond). 2004.

Levine JA. Non-exercise activity thermogenesis (NEAT). Proc Nutr Soc. 2005.

Hall KD, Guo J. Obesity Energetics: Body Weight Regulation and the Effects of Diet Composition. Gastroenterology. 2017.

FAO. Human Energy Requirements. Report of a Joint FAO/WHO/UNU Expert Consultation, 2004.

HOLLIS, James H. The effect of mastication on food intake, satiety and body weight. Physiology & Behavior, Amsterdam, v. 193, pt. B, p. 242–245, 1 set. 2018. DOI: 10.1016/j.physbeh.2018.04.027.

PEDERSEN, Anne M. Lynge et al. Saliva and gastrointestinal functions of taste, mastication, swallowing and digestion. Oral Diseases, Oxford, v. 8, n. 3, p. 117–129, maio 2002. DOI: 10.1034/j.1601-0825.2002.02851.x.

HOPPER, Z.; IRVING, C.; DUNCAN, B.; ROBERTS, S. Energy accuracy of nutritional fluids provided in hospital: comparing nutrition label values against direct bomb calorimetry. British Journal of Nutrition, Cambridge, 2025. DOI: 10.1017/S0007114525000601.

WIERDSMA, N. J.; PETERS, J. H. C.; VAN BOKHORST-DE VAN DER SCHUEREN, M. A. E.; MULDER, C. J. J.; METGOD, I.; VAN BODEGRAVEN, A. A. Bomb calorimetry, the gold standard for assessment of intestinal absorption capacity: normative values in healthy ambulant adults. Journal of Human Nutrition and Dietetics, Oxford, v. 27, supl. 2, p. 57–64, 2014. DOI: 10.1111/jhn.12113.

Se deseja marcar uma consulta, mande mensagem no email profbaeta@gmail.com ou entre no site www.lucabaeta.com.br ou ainda, se preferir, mande mensagem no instagram @profbaeta

Neste episódio duplo, falamos sobre percepção de risco sobre tomadas de decisão em saúde e as principais formas de construção do conhecimento.

----------------------------------------

Refs.:

The Role of Patient Engagement in Addressing Parents’ Perceptions About Immunizations

⁠https://jamanetwork.com/journals/jama/article-abstract/2633667⁠

The Role of Risk Perception in Flu Vaccine Behavior among African‐American and White Adults in the United States

⁠https://onlinelibrary.wiley.com/doi/abs/10.1111/risa.12790⁠

Risk perception of non-communicable diseases: A systematic review on its assessment and associated factors

⁠https://pubmed.ncbi.nlm.nih.gov/37262079/⁠

Epistemologia I

⁠https://www.deviante.com.br/podcasts/scicast-406/⁠

Epistemologia II

⁠https://www.deviante.com.br/podcasts/scicast-415/⁠

Epistemologia III

⁠https://www.deviante.com.br/podcasts/scicast-448/⁠

The Four Causes of Behavior

⁠https://pmc.ncbi.nlm.nih.gov/articles/PMC2600470/⁠

The study of Behavior

⁠https://www.cambridge.org/core/books/study-of-behavior/E07E5515AC2DBD6B4AFC5531898863EB⁠

⁠https://www.iea.usp.br/midiateca/video/videos-2018/jerry-hogan-study-of-behavior-organization-methods-and-principles⁠

Thirteen Theories of Human Nature

⁠https://www.amazon.com.br/Thirteen-Theories-Nature-Leslie-Stevenson/dp/0190604727⁠

Tratado da Natureza Humana

⁠https://www.amazon.com.br/Tratado-natureza-humana-David-Hume/dp/8571399018⁠

O problema da Indução: de Hume a Popper

⁠https://revistas.unisinos.br/index.php/controversia/article/view/5521⁠

Se deseja marcar uma consulta, mande mensagem no email profbaeta@gmail.com ou entre no site www.lucabaeta.com.br ou ainda, se preferir, mande mensagem no instagram @profbaeta

Neste episódio duplo, falamos sobre percepção de risco sobre tomadas de decisão em saúde e as principais formas de construção do conhecimento.

----------------------------------------

Refs.:

The Role of Patient Engagement in Addressing Parents’ Perceptions About Immunizations

https://jamanetwork.com/journals/jama/article-abstract/2633667

The Role of Risk Perception in Flu Vaccine Behavior among African‐American and White Adults in the United States

https://onlinelibrary.wiley.com/doi/abs/10.1111/risa.12790

Risk perception of non-communicable diseases: A systematic review on its assessment and associated factors

https://pubmed.ncbi.nlm.nih.gov/37262079/

Epistemologia I

https://www.deviante.com.br/podcasts/scicast-406/

Epistemologia II

https://www.deviante.com.br/podcasts/scicast-415/

Epistemologia III

https://www.deviante.com.br/podcasts/scicast-448/

The Four Causes of Behavior

https://pmc.ncbi.nlm.nih.gov/articles/PMC2600470/

The study of Behavior

https://www.cambridge.org/core/books/study-of-behavior/E07E5515AC2DBD6B4AFC5531898863EB

https://www.iea.usp.br/midiateca/video/videos-2018/jerry-hogan-study-of-behavior-organization-methods-and-principles

Thirteen Theories of Human Nature

https://www.amazon.com.br/Thirteen-Theories-Nature-Leslie-Stevenson/dp/0190604727

Tratado da Natureza Humana

https://www.amazon.com.br/Tratado-natureza-humana-David-Hume/dp/8571399018

O problema da Indução: de Hume a Popper

https://revistas.unisinos.br/index.php/controversia/article/view/5521

Se deseja marcar uma consulta, mande mensagem no email profbaeta@gmail.com ou entre no site www.lucabaeta.com.br ou ainda, se preferir, mande mensagem no instagram @profbaeta