Exploring the Science of Aging: Do Longevity Drugs Hold the Key to a Longer Life?
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Exploring the Science of Aging: Do Longevity Drugs Hold the Key to a Longer Life?
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Welcome to Longevity Lowdown. Today we ask: Do longevity drugs work?
“As elixirs of life go, long-term fasting is a surprising candidate. Yet it seems to work.” Experiments on species from nematode worms to rhesus monkeys show that near-starvation prolongs lifespan, and “short-term ones suggest similar physiological changes happen” in humans.
Drugs promise an easier route. Rapamycin, an immune suppressant, blocks a key growth pathway and has extended mouse lifespans by up to 25 percent. Metformin, a decades-old diabetes pill, is now in a major trial to see if it can delay ageing in people.
Then there are senolytics, designed to clear out worn-out cells. Early human tests hint they might ease arthritis and lung disease. Yet most evidence still comes from animals or small studies. Whether these treatments can safely boost our healthspan—or lifespan—remains an open question.
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